An observational study in Catheter-Associated Urinary Tract Infections (CAUTIs), sponsored by Chinese University of Hong Kong. Not yet recruiting at 1 site in Hong Kong. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-13.
Sponsored by Chinese University of Hong Kong · Observational
A self-controlled pilot study to evaluate the use of oral bacterial immunotherapy for prevention of catheter-associated urinary tract infection.
The aim of the study is to prospectively evaluate Uromune as a potential non-antibiotic prophylactic strategy for catheter-associated urinary tract infection in patients with long-term catheterization.
Chinese University of Hong Kong is the lead sponsor of 1,446 studies on the registry; 467 are open to participants now.
Of its 6 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patient with long-term indwelling Foley catheter with at least one documented catheter-associated urinary tract infection episode or hospital admission for suspected urinary tract infection in the preceding 6 months.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Immunosuppression state including:
- Primary immunodeficiency - Systemic immunosuppressive therapy e.g. steroid, chemotherapy, biologics, or immunosuppressants - Known HIV carrier or AIDS patient
Standard treatment course: oral bacterial immunotherapy (Sublingual Vaccine Uromune) MV140
Drug: Uromune
Oral bacterial immunotherapy (Sublingual Vaccine Uromune) MV140
Difference in total number of symptomatic catheter-associated urinary tract infection (CAUTI) requiring hospital admission
By comparing the total number of symptomatic catheter-associated urinary tract infection (CAUTI) requiring hospital admission during the 6-month post-intervention period and the 6-month pre-intervention period.
Time frame: 6-month post-intervention period compared with the 6-month pre-intervention period
Difference in total number of emergency department visits for suspected UTI or urosepsis
By comparing the total number of emergency department visits for suspected UTI or urosepsis during the 6-month post-intervention period and the 6-month pre-intervention period.
Time frame: 6-month post-intervention period compared with the 6-month pre-intervention period
Difference in total number of antibiotic courses
By comparing the total number of antibiotic courses during the 6-month post-intervention period and the 6-month pre-intervention period.
Time frame: 6-month post-intervention period compared with the 6-month pre-intervention period
Difference in total number of antibiotic days of therapy
By comparing the total number of antibiotic days of therapy during the 6-month post-intervention period and the 6-month pre-intervention period.
Time frame: 6-month post-intervention period compared with the 6-month pre-intervention period
Difference in time to first CAUTI admission
By comparing the time to first catheter-associated urinary tract infection admission during the 6-month post-intervention period and the 6-month pre-intervention period.
Time frame: 6-month post-intervention period compared with the 6-month pre-intervention period
Difference in total number of unplanned catheter changes or catheter blockage events
By comparing the total number of unplanned catheter changes or catheter blockage events during the 6-month post-intervention period and the 6-month pre-intervention period.
Time frame: 6-month post-intervention period compared with the 6-month pre-intervention period
Difference in total number of all-cause hospital admissions
By comparing the total number of all-cause hospital admissions during the 6-month post-intervention period and the 6-month pre-intervention period.
Time frame: 6-month post-intervention period compared with the 6-month pre-intervention period
Difference in total number of adverse events related to immunotherapy
By comparing the total number of adverse events related to immunotherapy during the 6-month post-intervention period and the 6-month pre-intervention period.
Time frame: 6-month post-intervention period compared with the 6-month pre-intervention period
Plan to share: Undecided
Start is estimated for Oct 2026; primary completion for Dec 2027, 14 months later.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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Chinese University of Hong Kong →