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Not yet recruitingNCT07849075MEMRIUpdated Sep 30, 2026

MEMRI: Memory Emergence Using MRI

An observational study in Not Applicable - Healthy Participants, Focus is the Memory System and Paediatric, sponsored by Paediatric Neuroimaging Research Group. Not yet recruiting. Open to participants aged 0 Weeks to 1 Week, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-30.

Sponsored by Paediatric Neuroimaging Research Group · Observational

Updated Sep 30, 2026Newly registeredGo to Updates ↓
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
20
Ages
0 Weeks to 1 Week
Sex
All
01

Study summary

Episodic memory is our ability to remember personal experiences, such as a birthday party or a visit to the park. This study aims to understand how this type of memory develops during the first two years of a baby's life. Researchers will use a safe, non-invasive brain scanning technique called magnetic resonance imaging (MRI) to study healthy babies from birth until they are two years old. By following the same children over time, researchers will see how the brain's memory system develops and how it becomes connected with other parts of the brain. The findings will help us understand how babies develop the ability to remember personal experiences. They will also provide new knowledge about how the human brain develops during the earliest stages of life.

02

Conditions studied

  • Not Applicable - Healthy Participants
  • Focus is the Memory System
  • Paediatric

Keywords

  • Memory
  • Neonatal
  • Paediatric
  • MRI
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In context

Lead sponsor

Paediatric Neuroimaging Research Group is the lead sponsor of 2 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
0 Weeks to 1 Week
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Participants in this study will be infants born at the John Radcliffe Hospital, Oxford at or after 35+0 weeks gestation with a postnatal age of \<7 days.

Inclusion criteria

  • Infants born at the John Radcliffe Hospital, Oxford
  • Infants born at or after 35+0 weeks gestation
  • Infants with a postnatal age of \<7 days
  • Infants for whom parents/legal guardians have given written informed consent for participation.

Exclusion criteria

Exclusion Criteria:

  • Hypoxic Ischaemic Encephalopathy (HIE)
  • Intraventricular haemorrhage (IVH) > grade II
  • Received any analgesics or sedatives in the last 24 hours
  • Congenital malformation or genetic condition known to affect neurological development
  • Born to mothers who have a history of substance abuse
  • Any MRI contradictions
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
20 participants (estimated)
Target follow-up
26 Months
Patient registry
Yes
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What researchers measure

Primary outcomes

  1. FMRI connectivity

    Differences in functional connectivity of spontaneous fMRI brain activity

    Time frame: Two years

Secondary outcomes

  1. Changes in fMRI connectivity

    Longitudinal changes in fMRI connectivity over the entire duration of the study

    Time frame: Two years

07

Study locations

No study locations are listed for this record.

08

Updates

1 registry update since Sep 25, 2026
Registered
First appeared on the registry. No changes since
Sep 30, 2026
Show all 1 update
  1. Sep 30, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

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Registry details

Key details

Study ID
NCT07849075
Lead sponsor
Paediatric Neuroimaging Research Group
Responsible party
Sponsor
First posted
Sep 30, 2026
Start date
Mar 1, 2027 (estimated)
Primary completion
Mar 1, 2030 (estimated)
Completion
Jul 1, 2031 (estimated)
Last update
Sep 30, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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