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Active, not recruitingNCT07824037sinus liftUpdated Sep 17, 2026

Endoscopic-Assisted Versus Conventional Crestal Sinus Lift

An interventional study of Endoscopic-guided Sinus lift and non- endoscopic sinus lift in Bone Defects, sponsored by Nahla Mahmoud Awad. Active, not recruiting at 1 site in Egypt. Open to participants aged 21 Years and older. Per ClinicalTrials.gov, last updated 2026-09-17.

Sponsored by Nahla Mahmoud Awad · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
24
Allocation
Randomized
Ages
21 Years and older
Sex
All
01

Study summary

To compare Endoscopic-Assisted Versus Conventional Crestal Sinus Lift; bone grafting will be performed, followed by implant placement. Membrane perforation rates, surgical time, and bone density changes will be evaluated.

Read the detailed description

Type of study design: A Randomized Clinical Trial Objective of the research: To compare Endoscopic-Assisted Versus Conventional Crestal Sinus Lift; bone grafting will be performed, followed by implant placement. Membrane perforation rates, surgical time, and bone density changes will be evaluated.

Steps of the research in short including the following:

  • The inclusion and exclusion criteria for patient selection. Inclusion criteria: Loss of one or more maxillary posterior tooth, Patients age≥21 years, Bone height was 4-7 mm, sufficient inter-arch space and mesio-distal width.

Exclusion criteria Parafunctional habits, Drug or alcohol abuse, uncontrolled systemic diseases that contraindicate implant surgery, pregnant women, Smokers.

  • Mention the source of the patients enrolled in the research All patients will be operated on and followed up at the Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Cairo University, Egypt.
  • A written informed consent form will be signed from the patientis required.
  • Description of the methodology. Radiographic assessment involved panoramic X-rays and cone-beam computed tomography (CBCT). CBCT analysis included evaluation of residual bone height, buccopalatal bone width, sinus pathology, bony septa, and precise measurement of Schneiderian membrane thickness at the planned implant sites Group 1(non-endoscopic-guided): Endoscopic evaluation was performed after complete osteotomy preparation and sinus membrane elevation using osteotomes.

Group 2 (Endoscopic-guided): Endoscopic evaluation was conducted after each drilling step, osteotome malleting, and bone graft placement to monitor sinus membrane integrity.

Sample size calculation.

  • Randomization in case of RCT. Patients will be divided into two groups based on treatment type using block randomization of block size 4. An independent statistician will generate the random sequence using a computer-generated random number list method by (https://www.randomizer.org/).
  • Number of visits \& follow up period. ( 4 visits)

Patients in both groups will be followed up at 24-hours, one, three, six, months postoperatively to assess this parameter:

  1. Membrane integrity intraoperative.
  2. Surgical intraoperative time.
  3. Radiographically, mean bone density will be measured (immediate post-operative and post 6 months CBCT)
02

Conditions studied

  • Bone Defects

Keywords

  • Maxillary sinus augmentation
  • Posterior maxillary implants
  • Sinus endoscopy
03

Who can participate

Ages eligible
21 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Loss of one or more maxillary posterior tooth, Patients age≥21 years, Bone height was 4-7 mm, sufficient inter-arch space and mesio-distal width.

Exclusion criteria

Exclusion Criteria:

  • Parafunctional habits, Drug or alcohol abuse, uncontrolled systemic diseases that contraindicate implant surgery, pregnant women, Smokers.
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Single group
Masking
Single (Outcomes assessor)
Enrollment
24 participants (actual)

Study arms

  • Experimental
    Endoscopic-guided sinus lift

    Endoscopic-guided sinus lifting

    Procedure: Endoscopic-guided Sinus lift

  • Placebo comparator
    non-endoscopic-guided sinus lift

    conventional sinus lift

    Procedure: non- endoscopic sinus lift

Interventions

  • ProcedureEndoscopic-guided Sinus lift

    12 patients in Group 2 (Endoscopic-guided): Endoscopic evaluation was conducted after each drilling step, osteotome malleting, and bone graft placement to monitor sinus membrane integrity.

  • Procedurenon- endoscopic sinus lift

    12 patients in Group 1(non-endoscopic-guided): Endoscopic evaluation was performed after complete osteotomy preparation and sinus membrane elevation using osteotomes.

05

What researchers measure

Primary outcomes

  1. Membrane integrity intraoperative.

    Membrane remains intact ( no perforation)

    Time frame: 24 hours

Secondary outcomes

  1. mean bone density

    CBCT

    Time frame: 6 months

06

Study locations

1 site
  • Cairo University
    Cairo, Cairo Governorate 12515, Egypt
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT07824037
Lead sponsor
Nahla Mahmoud Awad
Collaborators
Cairo University
Responsible party
Nahla Mahmoud Awad (associate professor of oral and maxillofacial surgery, Cairo University) — Sponsor-investigator
First posted
Sep 17, 2026
Start date
May 25, 2026
Primary completion
May 31, 2028 (estimated)
Completion
Jul 31, 2028 (estimated)
Last update
Sep 17, 2026

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in May 2026. You cannot join it, but the record below documents what was studied.

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