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CompletedNCT07810387Updated Sep 9, 2026

Sex Differences in Knee Strength and Speed in Male and Female Football Players

An observational study in Isokinetic Test, Force-velocity Profile and Soccer Performance, sponsored by Haute Ecole ARC Sante. Completed at 1 site in France. Open to participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-09.

Sponsored by Haute Ecole ARC Sante · Observational

Study type
Observational
Model
Case-control
Time perspective
Cross-sectional
Enrollment
37
Ages
18 Years to 35 Years
Sex
All
01

Study summary

Force-velocity (F-V) profiling is increasingly used to describe the mechanical capacities of the knee extensors and knee flexors in football, but almost all available reference data come from male players. It is not established whether male and female players differ in the parameters of the isokinetic force-velocity relationship, or whether any such differences persist once differences in body size are accounted for.

This single-centre, cross-sectional observational study compared the isokinetic force-velocity profiles of the knee extensors and knee flexors between male and female competitive football players. Eligible participants were competitive players aged 18 to 35 years, training at least three times per week, free of current lower limb pain or injury and with no history of knee or hip surgery. During a single testing session, participants performed bilateral concentric isokinetic knee extension and flexion at five angular velocities (30, 60, 180, 240 and 300 degrees per second) on an isokinetic dynamometer, after a standardised warm-up, individual gravity correction and a familiarisation session.

For each participant, limb and muscle group, peak torque was regressed against angular velocity to fit an individual linear torque-angular velocity relationship. The following parameters were derived: theoretical maximal torque (F0), theoretical maximal angular velocity (V0), the slope of the relationship, maximal theoretical power (Pmax), and torque and power at the extremes of the tested velocity range. The participant, defined as the mean of both limbs, was the unit of analysis.

Male and female players were compared in absolute terms and after adjustment for body size, using ratio scaling to body mass, log-log allometric models and analysis of covariance with body mass and age as covariates. Secondary comparisons included the conventional hamstring-to-quadriceps ratio, inter-limb asymmetry and the orientation of the profile (F0/V0 ratio).

The purpose of the study is to determine which sex differences in isokinetic force-velocity parameters are explained by body size and which persist after adjustment, in order to establish whether reference values obtained in male players can legitimately be applied to female players.

02

Conditions studied

  • Isokinetic Test
  • Force-velocity Profile
  • Soccer Performance
  • Female Athletes
03

In context

Lead sponsor

Haute Ecole ARC Sante is the lead sponsor of 4 studies on the registry; 2 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 35 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

male and female football players, Players were recruited from regional football clubs competing at national level

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • male or female football players aged 18-35 years;
  • participation in competitive football for at least three consecutive years;
  • a minimum of three weekly training sessions;
  • no current pain or injury of the lower limbs;
  • no history of knee or hip surgery;
  • ability to perform maximal voluntary contractions during isokinetic testing;
  • an adequate physical activity level (Tegner ≥ 7; Marx ≥ 12).

Exclusion criteria

Exclusion Criteria:

  • any medical condition limiting the test or any injury/surgery of the lower limb from the last 2 years
05

Study design

Observational model
Case-control
Time perspective
Cross-sectional
Enrollment
37 participants (actual)
Target follow-up
1 Day
Patient registry
Yes

Groups and cohorts

  • Male football players

    Diagnostic Test: Isokinetic test

  • Female football players

    Diagnostic Test: Isokinetic test

Interventions

  • Diagnostic testIsokinetic test

    The expected results should improve the objective characterisation of residual deficits, inform the selection and prioritisation of the tests used in return-to-sport assessments, and contribute to evidence-based rehabilitation practice. The project thereby contributes to improving quality of care and to generating knowledge that is useful to the health professionals managing this population. No procedure is added to routine care, and the care pathway is not modified.

06

What researchers measure

Primary outcomes

  1. Isokinetic force-velocity profile of the knee extensors and knee flexors

    Force-velocity profile of the knee extensors and knee flexors derived from isokinetic dynamometry, compared between male and female competitive football players. \[ e.g. theoretical maximal force F0, theoretical maximal velocity V0, and the slope of the force-velocity relationship, with units.\]

    Time frame: Day 1(single isokinetic testing session)

07

Study locations

1 site
  • Orthosport Center
    Domont, 95330, France
08

References and documents

Publications

  • Alcazar J, Csapo R, Ara I, Alegre LM. On the Shape of the Force-Velocity Relationship in Skeletal Muscles: The Linear, the Hyperbolic, and the Double-Hyperbolic. Front Physiol. 2019 Jun 19;10:769. doi: 10.3389/fphys.2019.00769. eCollection 2019. PubMed 31275173 ↗
  • Lopez-Valenciano A, Raya-Gonzalez J, Garcia-Gomez JA, Aparicio-Sarmiento A, Sainz de Baranda P, De Ste Croix M, Ayala F. Injury Profile in Women's Football: A Systematic Review and Meta-Analysis. Sports Med. 2021 Mar;51(3):423-442. doi: 10.1007/s40279-020-01401-w. Epub 2021 Jan 12. PubMed 33433863 ↗
  • Morin JB, Samozino P. Interpreting Power-Force-Velocity Profiles for Individualized and Specific Training. Int J Sports Physiol Perform. 2016 Mar;11(2):267-72. doi: 10.1123/ijspp.2015-0638. Epub 2015 Dec 17. PubMed 26694658 ↗
  • Costello JT, Bieuzen F, Bleakley CM. Where are all the female participants in Sports and Exercise Medicine research? Eur J Sport Sci. 2014;14(8):847-51. doi: 10.1080/17461391.2014.911354. Epub 2014 Apr 25. PubMed 24766579 ↗
  • Emmonds S, Heyward O, Jones B. The Challenge of Applying and Undertaking Research in Female Sport. Sports Med Open. 2019 Dec 12;5(1):51. doi: 10.1186/s40798-019-0224-x. PubMed 31832880 ↗

Individual participant data

Plan to share: No

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Jun 2025 to primary completion in Aug 2025, 2 months.

How these figures are worked out, and which studies are left out of them.

Registered
Aug 28, 2026
First posted
Sep 9, 2026
StartActual
Jun 30, 2025
Primary completionActual
Aug 31, 2025
CompletionActual
Aug 31, 2025
Last update
Sep 9, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 9, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07810387
Lead sponsor
Haute Ecole ARC Sante
Responsible party
Forelli Florian (Forelli Florian, Haute Ecole ARC Sante) — Principal investigator
First posted
Sep 9, 2026
Start date
Jun 30, 2025
Primary completion
Aug 31, 2025
Completion
Aug 31, 2025
Last update
Sep 9, 2026

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

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