A Phase 1 interventional study of Eloralintide and Combined oral contraceptive in Obesity and Overweight, sponsored by Eli Lilly and Company. Not yet recruiting at 2 sites in United States. Open to female participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-08.
Sponsored by Eli Lilly and Company · Phase 1, Interventional, and Basic science
The main purpose of this study is to evaluate how eloralintide (LY3841136) effects the way the body processes oral contraceptive in female participants with obesity or overweight. For each participant, the study will last about 8 months and will include 3 stays in the Clinical Research Unit (CRU), each lasting between 6 - 8 nights.
Exclusion Criteria:
Eloralintide administered subcutaneously (SC), combined oral contraceptive administered orally
Drug: Eloralintide · Drug: Combined oral contraceptive
Eloralintide administered SC
Also known as: LY3841136
levonorgestrel and ethinyl estradiol administered orally
Pharmacokinetics (PK): Area Under the Concentration Versus Time Curve from Time Zero to Infinity (AUC[0-inf]) of Ethinyl Estradiol and Levonorgestrel
Time frame: Baseline through Day 128
PK: Maximum Concentration (Cmax) of Ethinyl Estradiol and Levonorgestrel
Time frame: Baseline through Day 128
PK: Time to Maximum Concentration (Tmax) of Ethinyl Estradiol and Levonorgestrel
Time frame: Baseline through Day 128
Plan to share: No
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This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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Eli Lilly and Company