An interventional study of conventional physical therapy and thoracic manibulation in Shoulder Impingement Syndrome, sponsored by Cairo University. Not yet recruiting. Open to participants aged 18 Years to 55 Years. Per ClinicalTrials.gov, last updated 2026-09-02.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
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Among 30 studies in Shoulder Impingement Syndrome by Cairo University — 14 open to participants now, 16 under way, none of them phase 3. Shoulder Impingement Syndrome · Cairo University.
Among the 30 studies in Shoulder Impingement Syndrome by Cairo University, this one has the largest planned enrollment of the 26 interventional ones that give a count, is one of 6 that started in 2026, is one of 26 with no phase, reaches primary completion later than 14 of the 15 other live ones, and was the 30th registered.
320 studies on the registry are indexed under Shoulder Impingement Syndrome; 62 are open to participants now.
Browse Shoulder Impingement Syndrome studies →14 of the 30 studies in Shoulder Impingement Syndrome by Cairo University are open now, in 1 country. Recruiting first, the newest first:
Cairo University · Sites in Egypt
Ages 18 wk–55 wk
Cairo University · Sites in Egypt
Ages 30–50
Cairo University · Sites in Egypt
Ages 20–40
Cairo University · Sites in Egypt
Ages 20–40
Cairo University · Sites in Egypt
Ages 19–70
By country, each count listing its studies:
Of the 32 Shoulder Impingement Syndrome studies recruiting now, 3 (9%) set no upper age limit and 25 (78%) stop at 75 or younger; 1 takes children under 18; 6 take healthy volunteers.
This study: 18 Years to 55 Years · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
30 studies; the count open now beside each. This study's row is marked.
First in 2020; this study’s year is marked. 6 started in 2026.
This study's planned enrollment of 80 is above the median of 54 across 271 interventional studies indexed under Shoulder Impingement Syndrome.
Median enrollment 49 across the 26 interventional studies, 64 across the 4 observational. Of the 10 that completed or were terminated, 0 (0%) have results posted.
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Cairo University is the lead sponsor of 4,941 studies on the registry; 1,457 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
4 of the studies in Shoulder Impingement Syndrome by Cairo University that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07608809Cairo UniversityEffect of Blood Flow Restriction Training Versus Pilates on Shoulder Impingement Syndrome | 2026-12-15 |
| NCT07601568Cairo UniversityPectoralis Minor Release in Patients With Subacromial Impingement Syndrome | 2027-01-01 |
| NCT07800559Cairo UniversityThe Combined Effect of Thoracic Manipulation and Instrument-assisted Soft Tissue Mobilization in Patients With Shoulder Impingement Syndrome | 2027-05-10 |
| NCT07645781Cairo UniversityCervical Stabilization Exercises IN Subacromial Impingement Syndrome | 2027-07-01 |
Add all 4 to your calendar (.ics) → With an account.
Among the 30 studies in Shoulder Impingement Syndrome by Cairo University, from their registry updates:
Nothing recorded among them since 2026-09-25.
This tab as a report to print or save as PDF → With an account.
This study will be conducted to investigate the combined effect of thoracic manipulation and instrument-assisted soft tissue mobilization in patients with shoulder impingement syndrome
Shoulder impingement syndrome (SIS) represents one of the most prevalent musculoskeletal disorders affecting the upper extremity, accounting for 44-65% of all shoulder complaints in clinical practice. The condition is characterized by mechanical compression of the rotator cuff tendons and subacromial bursa beneath the coracoacromial arch during arm elevation, resulting in pain, inflammation, and reduced quality of life. Thoracic spinal manipulation aims to restore mobility and optimize scapular positioning. Studies have shown that adding Maitland thoracic manipulation or Mulligan SNAGs to exercise leads to superior improvements in pain and range of motion.Thoracic spine manipulation (TSM) is one of the techniques that can be used to gain thoracic mobility in peoples with shoulder dysfunction Instrument-assisted soft tissue mobilization (IASTM) uses specialized tools to treat myofascial restrictions. It triggers a localized inflammatory response that initiates healing and remodeling. While promising in tendinopathy cases, there is a significant evidence gap regarding its efficacy when combined with joint-based manual therapy for SIS. Investigating the synergistic effects of combining these regional and local interventions with foundational scapular stabilization exercises will provide a comprehensive, evidence-based framework that is currently lacking in the literature.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Cancer (malignancy)
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Twenty patients with shoulder impingement syndrome will receive conventional physical therapy three times per week for 6 weeks
Other: conventional physical therapy
twenty patients with shoulder impingement syndrome will receive thoracic manibulation plus conventional physical therapy three times per week for 6 weeks
Other: conventional physical therapy · Other: thoracic manibulation
twenty patients with shoulder impingement syndrome will receive conventional physical therapy and instrument-assisted soft tissue mobilization three times per week for 6 weeks
Other: conventional physical therapy · Other: instrument assisted soft tissue mobilization
twenty patients with shoulder impingement syndrome will receive thoracic manipulation + instrument-assisted soft tissue mobilization. The conventional physical therapy three times per week for 6 weeks
Other: conventional physical therapy · Other: thoracic manibulation · Other: instrument assisted soft tissue mobilization · Other: thoracic manipulation and instrument-assisted soft tissue mobilization
the patients will receive conventional physical therapy in the form of transcutaneous electrical nerve stimulation, ultrasound, and therapeutic exercise. The exercise includes range of motion exercises, stretching, scapular stabilization exercises, and rotator cuff strengthening.
With the participant in a prone position, the therapist will apply a high-velocity, short-lever, posterior-to-anterior (P-A) thrust. The thrust will be directed toward the spinous or transverse processes of the hypomobile thoracic vertebrae. Thoracic thrust manipulation demonstrated to manipulate specific thoracic segment mainly the mid-thoracic, plus conventional physical therapy.
The IASTM technique will be performed for 20 seconds parallel to the muscle fibers, followed by 20 seconds perpendicular to the muscle fibers, with the instrument held at a 45° angle to the skin. The beveled side of the M2T blade will be in contact with the skin. Stroke pressure and speed will be modified according to the participant's tolerance to avoid causing pain and according to the depth of the treated muscle plus conventional physical therapy.The technique will be applied to the pectoral muscles, shoulder rotator cuff musculature, and periscapular musculature, including the upper, middle, and lower fibers of the trapezius, rhomboids major and minor, teres major, and latissimus dorsi
the patients will receive The IASTM technique will be performed for 20 seconds parallel to the muscle fibers followed by 20 seconds perpendicular to the muscle fibers, with the instrument held at a 45° angle to the skin plus thoracic manibulation in which the therapist will apply a high-velocity, short-lever, posterior-to-anterior (P-A) thrust. The thrust will be directed toward the spinous or transverse processes of the hypomobile thoracic vertebrae. Thoracic thrust manipulation demonstrated to manipulate specific thoracic segments, mainly the mid-thoracic, plus conventional physical therapy. finally, the pateitns will recieve conventional physical therapy
upper limb disability
Disabilities of the arm, shoulder and hand (Quick DASH) questionnaire will be used toassess upper limb diability.the QuickDASH only contains 11 items .It is a questionnaire that measures an individual's ability to complete tasks, absorb forces, and severity of symptoms.The QuickDASH tool uses a 5-point Likert scale from which the patient can select an appropriate number corresponding to his/her severity/function level.The QuickDASH outcome measure is designed to be used on patients presenting with one or more disabilities of the arm, shoulder, and hand. Scoring with 100 is more severe disability, and zero mean no disability.
Time frame: up to six weeks
pain intensity
neumerical pain rating scale will be used to assess pain. It consists of a line, often 10 cm long (100mm); its ends are generally labelled with verbal pain anchors (e.g., "no pain" and "pain as bad as it could be"). Patients are asked to indicate the point along the line from 0-10 cm marked in 1 cm increments where 0 cm represents no pain and 10 cm the most severe pain imaginable
Time frame: up to 6 weeks
shoulder range of motion
The Digital goniometer will be used to assess shoulder range of motion.
Time frame: up to six weeks
shoulder proprioception (joint position error)
shoulder joint position error will be assessed by a smartphone clinometer application. Proprioception test was done by moving the participant's arms from the starting position (0 degrees) to the target angles. The arm remained at each target angle for 5 seconds, allowing the subjects to memorize the position before returning to the starting position. Subsequently, the subjects were instructed to independently move their arms towards each target angle.
Time frame: up to six weeks
life disability
World Health Organization Quality of Life BREF will be used to assess life disability. The WHOQOL-BREF is a 26-item instrument that assesses quality of life across four domains: physical health (items 3, 4, 10, 15, 16, 17, and 18), psychological health (items 5, 6, 7, 11, 19, and 26), social relationships (items 20, 21, and 22), and environment (items 8, 9, 12, 13, 14, 23, 24, and 25). Items 1 and 2 assess overall quality of life and general health, respectively. Each item is rated on a 5-point Likert scale from 1 to 5. Items 3 and 4 are reverse-scored. For each domain, the item scores are averaged and multiplied by 4, producing a domain score ranging from 4 to 20, with higher scores indicating better quality of life.
Time frame: up to six weeks
pressure pain threshold
pressure pain threshold wil be assessed by algometer.During the assessment, the patient is instructed to indicate the exact moment the sensation transitions from comfortable pressure to the onset of pain, effectively translating a subjective experience into an objective, measurable value (typically recorded in kg/cm² or Newtons).
Time frame: up to six weeks
No study locations are listed for this record.
Start is estimated for Sep 2026; primary completion for May 2027, 8 months later.
Of 170 non-industry interventional studies with no phase under Shoulder Impingement Syndrome, half reached primary completion within 11 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 24. This study's planned 8 months is below that.
Counting every sponsor, half of 172 studies reached it within 12 months; a quarter within 5 and three quarters within 24.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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Shoulder Impingement Syndrome →