An interventional study of Combined Antioxidant Nutrition and Facial Exercise Program in Facial Skin Aging and Wrinkle Severity, sponsored by University of Zakho. Not yet recruiting. Open to female participants aged 45 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-28.
Sponsored by University of Zakho · Not applicable, Interventional, and Treatment
This randomized controlled trial will evaluate the effects of a 12-week combined antioxidant-rich nutrition and facial exercise program on skin quality and wrinkle severity in middle-aged women. Participants will be randomly assigned to an intervention group or a control group. The intervention group will follow a structured antioxidant-rich dietary program combined with facial exercises, while the control group will maintain their usual lifestyle. Skin quality and wrinkle-related outcomes will be assessed at baseline and after the 12-week intervention using standardized objective measurements
University of Zakho is the lead sponsor of 2 studies on the registry; 2 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Inclusion Criteria:
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Inclusion Criteria:
Female participants aged 45-50 years. Willing and able to participate in the 12-week intervention program. Willing to follow the assigned dietary and facial exercise program. Willing to maintain their usual skincare routine unless otherwise instructed by the study protocol. Able to provide .
Exclusion Criteria:
Current smoking. Facial aesthetic procedures such as botulinum toxin injections, dermal fillers, laser treatment, chemical peels, or similar procedures within the predefined period before enrollment. Current dermatological disease or skin condition that may affect facial skin measurements. Uncontrolled chronic medical conditions that may influence skin health or participation in the intervention. Planned initiation of new skincare treatments, cosmetic products, or aesthetic procedures during the 12-week study period. Inability to perform the facial exercise program safely or comply with the dietary intervention and study procedures
Exclusion Criteria:
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Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants in the intervention group will follow a 12-week combined antioxidant-rich nutrition and facial exercise program
Behavioral: Combined Antioxidant Nutrition and Facial Exercise Program
Participants in the control group will maintain their usual diet, skincare routine, and daily lifestyle without receiving the study intervention during the 12-week period
Participants in the intervention group will complete a 12-week combined program consisting of an antioxidant-rich dietary intervention and structured facial exercises. The dietary component will emphasize regular consumption of antioxidant-rich foods, while the facial exercise component will target major facial muscle groups according to a standardized exercise protocol. Participants will be instructed to follow the program throughout the 12-week intervention period
Change in Mean Crow's Feet Wrinkle Depth
Change in the mean bilateral crow's feet wrinkle depth from baseline to week 12, assessed using standardized three-dimensional skin imaging. Measurements will be obtained from both sides of the face and averaged to provide the participant-level value. Lower post-intervention values indicate improvement in wrinkle depth
Time frame: Baseline to 12 weeks
No study locations are listed for this record.
Plan to share: No — Individual participant data (IPD) will not be shared because the data contain confidential participant information and were collected under ethical approval with provisions for maintaining participant privacy and confidentiality.
No publications or documents are linked to this record.
Start is estimated for Aug 2026; primary completion for Aug 2026, 0 months later.
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This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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University of Zakho