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RecruitingNCT07790874Updated Aug 27, 2026

Effects of Oculomotor Exercises in Patients With Non Traumatic Cervical Dizziness

An interventional study of Sustained Natural Apophyseal Glides and Oculomotor exercises and Sustained Natural Apophyseal Glides in Cervical, Dizziness and Disability, sponsored by Riphah International University. Recruiting at 1 site in Pakistan. Open to participants aged 20 Years to 40 Years. Per ClinicalTrials.gov, last updated 2026-08-27.

Sponsored by Riphah International University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Started Aug 2026; still recruiting 2 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
48
Allocation
Randomized
Ages
20 Years to 40 Years
Sex
All
01

Study summary

To investigate the effects of oculomotor exercises on pain disability, dizziness and gaze stability in patients with non-traumatic cervical dizziness.

Read the detailed description

A randomized controlled trial compared routine exercise with a combination of oculomotor exercises (OEs) and manual myofascial techniques (MFT) in patients with chronic non-specific neck pain (CNNP). Thirty-eight participants were randomly allocated into two groups, and both groups completed a six-week exercise program, while the intervention group additionally received OEs and manual MFT. Outcome measures included pain intensity, cervical range of motion (ROM), proprioception, kinesiophobia, and disability. Both groups showed significant improvements after treatment. However, the group receiving OEs and manual MFT demonstrated significantly greater improvements in cervical ROM, pain, disability, proprioception, and kinesiophobia compared to the routine exercise group. These findings suggest that adding OEs and manual MFT may enhance rehabilitation outcomes in patients with CNNP.

A comparative study evaluated manual therapy alone versus manual therapy combined with proprioception training in patients with cervicogenic dizziness (CGD) and chronic neck pain (CNP). Twenty participants were divided into two groups, with ten patients in each group. One group received manual therapy, while the other received manual therapy along with proprioception training. Outcome measures included joint position error sense (JPSE), smooth pursuit performance, Dizziness Handicap Inventory (DHI), and dizziness visual analogue scale (VAS). Both groups showed significant improvements following treatment; however, the combined therapy group demonstrated greater improvements in proprioception, eye movement control, dizziness severity, and disability. These findings indicate that adding proprioception training to manual therapy may provide superior therapeutic benefits for patients with CGD and CNP.

A randomized controlled trial investigated the effectiveness of tactile discrimination training (TDT) and OEs in individuals with chronic neck pain. Fifty-seven participants were randomly assigned to a TDT group, an OE group, or a control group that received no intervention. Both intervention groups underwent treatment three times per week for four weeks. Outcomes included pain intensity, neck pain-related disability, pressure pain thresholds, mechanical temporal summation of pain, and conditioned pain modulation. Significant improvements in pain intensity and neck-related disability were observed in both intervention groups compared with the control group. However, the OEs group demonstrated greater reductions in pain intensity and greater improvements in pressure pain thresholds than the TDT group. These findings suggest that both TDT and OEs may be effective in reducing pain and disability in patients with chronic neck pain, with OEs providing greater clinical benefits.

A multicenter randomized controlled trial compared three vestibular rehabilitation approaches in patients with unilateral peripheral vestibular dysfunction. Thirty-four participants were randomly assigned to customized vestibular rehabilitation therapy, generic vestibular rehabilitation therapy using Cawthorne-Cooksey exercises, or vestibulo-ocular reflex (VOR) adaptation exercises, with 23 participants completing the study. Outcomes included dizziness-related disability, balance, and visual stability. All three intervention groups demonstrated significant improvements following treatment. However, participants performing gaze stabilization exercises demonstrated greater reductions in dizziness-related disability and superior improvements in balance. These findings highlight the potential importance of gaze stabilization training as a component of vestibular rehabilitation, particularly in individuals with gaze stability impairments.

A randomized controlled trial compared the short- and long-term effects of two manual therapy approaches in patients with chronic cervicogenic dizziness. Eighty-six participants were randomly allocated to groups receiving SNAGs with self-SNAG exercises, passive joint mobilizations with ROM exercises, or a placebo intervention. Participants received treatment sessions over six weeks, with outcomes assessed up to 12 months. Both manual therapy groups demonstrated significant reductions in dizziness intensity and frequency, improvements in cervical ROM, and lower dizziness-related disability compared with the placebo group. The SNAG intervention produced greater improvements in cervical mobility and balance performance, while passive joint mobilization resulted in greater improvements in dizziness-related disability and pain reduction.

A randomized controlled study investigated the effects of oculomotor exercises in patients with chronic non-specific neck pain and associated visual complaints. Thirty-two participants were randomly allocated into two groups. The control group received stretching exercises for the sternocleidomastoid and anterior scalene muscles along with neck isometric exercises, whereas the experimental group received the same conventional treatment in addition to a structured OEs program consisting of saccadic eye movements, smooth pursuit exercises, convergence training, and gaze stabilization exercises. Outcomes included pain intensity, the Neck Disability Index (NDI), gaze stability, and visual symptoms. Significant improvements were observed in neck pain, disability, gaze stability, and visual complaints following the intervention. Improvements in eye-head coordination and sensorimotor control were also reported, suggesting that OEs may be beneficial for reducing pain and disability while improving gaze stability and visual function in patients with chronic neck pain.

A randomized controlled trial compared OEs combined with a cervical proprioceptive training program with cervical proprioceptive training alone in patients with chronic neck pain. Forty-eight patients were equally randomized into two groups. The intervention was applied three times per week for eight weeks, resulting in 24 sessions. Both groups demonstrated significant improvements in deep cervical flexor muscle activation and function. However, greater improvements in deep cervical flexor activation and functional outcomes were observed in the group receiving combined cervical proprioceptive and oculomotor training. These findings suggest that combining OEs with cervical proprioceptive training may provide additional benefits for improving clinical symptoms in patients with chronic neck pain.

A randomized controlled trial evaluated the efficacy of a self-exercise program in patients with cervicogenic dizziness. Thirty-two participants were randomly allocated to a self-exercise group or a control group. The self-exercise program included muscle strengthening, cervical mobilization, and osteopathic manipulative exercises performed at home, while the control group received no specific exercise intervention. Outcomes were assessed using the DHI, NDI, VAS, cervical ROM, and posturography tests. The self-exercise group demonstrated significantly greater improvements in dizziness-related disability and neck disability compared with the control group. However, no significant between-group differences were observed in pain intensity, cervical ROM, or balance measures.

A randomized controlled trial evaluated the effectiveness of adding sensorimotor training, including oculomotor and gaze stability exercises, to standard neck exercises in patients with chronic neck pain and dizziness. Seventy-two patients were randomly assigned to a standard neck exercise group or a combined sensorimotor training group. The intervention lasted ten weeks, and outcomes included neck pain intensity, disability, dizziness, balance, and gaze stability. The combined intervention demonstrated significantly greater improvements in dizziness, gaze stability, and balance compared with standard neck exercises. Greater reductions in neck pain and disability were also reported, suggesting that incorporating sensorimotor and oculomotor exercises may enhance rehabilitation outcomes in patients with chronic neck pain and associated dizziness.

A randomized controlled trial investigated the postural and clinical outcomes of SNAGs treatment in patients with cervicogenic dizziness. Eighty-nine patients were randomly assigned to either a SNAGs intervention group or a placebo group receiving a detuned laser. Both groups received six intervention sessions over four weeks. The SNAGs group demonstrated a significant reduction in perceived dizziness, neck disability, and pain, along with significant improvements in cervical ROM and selected posturographic parameters.

A randomized controlled trial investigated the short-term effects of a traction-manipulation protocol on dizziness intensity and disability in patients with cervicogenic dizziness. Forty participants were randomly assigned to an intervention group receiving traction-manipulation treatment or a control group that remained in a supine position. The intervention was delivered according to safety recommendations. Outcomes included dizziness intensity, pain intensity, DHI, cervical ROM, and balance, assessed at 48 hours and one month after treatment. The intervention group demonstrated significantly greater improvements in dizziness, neck pain, DHI scores, and upper cervical mobility compared with the control group at both follow-up periods. Postural stability also improved significantly in the intervention group at one month. These findings indicate that traction-manipulation may be effective for reducing dizziness and pain while improving cervical function and balance in patients with cervicogenic dizziness.

02

Conditions studied

  • Cervical
  • Dizziness
  • Disability
  • Pain

Browse trials for

Keywords

  • cervical dizziness
  • Oculomotor Exercises
  • Gaze Stability
  • Non Traumatic
03

In context

Dizziness

226 studies on the registry are indexed under Dizziness; 56 are open to participants now.

This study's planned enrollment of 48 is above the median of 43 across 170 interventional studies indexed under Dizziness.

Browse Dizziness studies →

Lead sponsor

Riphah International University is the lead sponsor of 2,193 studies on the registry; 650 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 40 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Both Males and Females
  • Age between 20 and 40 years with nontraumatic cervical dizziness.
  • Patients experiencing symptoms of cervicogenic dizziness for at least 3 months (chronic cervicogenic dizziness)
  • Patients having a Numeric Pain Rating Scale (NPRS) score greater than or equal to 3
  • Patient with positive Flexion Rotation Test (FRT)
  • Cervical Torsion Test
  • Patients have never received oculomotor exercises and SNAGS before.

Exclusion criteria

Exclusion Criteria:

  • History of trauma or recent surgery to the head, face, neck, or chest.
  • Diagnosis of central vertigo (e.g., brainstem or cerebellar pathology).
  • Presence of vestibular-origin vertigo, such as benign paroxysmal positional vertigo (BPPV).
  • Triage (Patients with traumatic cervical spine injury, Cervical arterial dysfunction and central vestibular disorders
  • Inability to perform exercises (e.g., due to cervical fracture)
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
48 participants (estimated)

Study arms

  • Experimental
    Sustained Natural Apophyseal Glides and Oculomotor Exercises

    Participants in Group A received moist heating pad, isometric exercises, Sustained Natural Apophyseal Glides, and oculomotor exercises including saccadic eye movements, smooth pursuit training, gaze stabilization, and head-eye coordination exercises.

    Other: Sustained Natural Apophyseal Glides and Oculomotor exercises

  • Active comparator
    Sustained Natural Apophyseal Glides

    Participants in Group B received standard physiotherapy, consisting of moist heating pad, isometric exercises, and Sustained Natural Apophyseal Glides

    Other: Sustained Natural Apophyseal Glides

Interventions

  • OtherSustained Natural Apophyseal Glides and Oculomotor exercises

    Sustained Natural Apophyseal Glides: The patient sat upright and actively moved the head in the direction that provoked dizziness. The therapist applied a sustained anterior glide to the targeted C1 or C2 vertebra during the movement. The technique was performed initially for 3 repetitions and progressed to 6 repetitions, with gentle overpressure added as tolerated. Oculomotor Exercises: The intervention included saccadic eye movements, smooth pursuit training, gaze stabilization, and head-eye coordination exercises. These exercises were performed with the head and/or eyes moving in controlled directions to improve gaze stability, eye-head coordination, and sensorimotor control.

    Also known as: SNAGs

  • OtherSustained Natural Apophyseal Glides

    he patient sat upright and actively moved the head in the direction that provoked dizziness. The therapist applied a sustained anterior glide to the targeted C1 or C2 vertebra during the movement. The technique was performed initially for 3 repetitions and progressed to 6 repetitions, with gentle overpressure added as tolerated.

06

What researchers measure

Primary outcomes

  1. Rating Scale of Gaze Stability

    Assesses gaze stability during head movements in sitting. It consists of three ratings: 0 indicates stable gaze, 1 indicates slightly irregular gaze stability, and 2 indicates repeatedly unstable gaze.

    Time frame: 4 weeks

  2. Neck Disability index

    It comprises of 10 items; 7 related to daily living activities, 2 related to pain and 1 related to concentration. Each item is scored from 0 to 5. Total score is expressed as a percentage, with higher scores related to greater disability. It has high test-retest reliability (ICC = 0.978)

    Time frame: 4 weeks

  3. Dizziness Handicap Inventory questionnaire

    A 25-item questionnaire assessing the functional, emotional, and physical effects of dizziness. Each item is scored as 0, 2, or 4, with a total score ranging from 0-100. Lower scores indicate less disability.

    Time frame: 4th week

  4. Universal Goniometer

    A commonly used instrument for measuring cervical range of motion. It demonstrates high test-retest reliability and inter-rater reliability.

    Time frame: 4 weeks

07

Study locations

1 of 1 sites recruiting
  • Independent Hospital
    Faisalābad, Punjab Province 38000, Pakistan
    Recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Aug 2026 (actual). Primary completion is estimated for Sep 2026, 1 month after the start.

Of 82 non-industry interventional studies with no phase under Dizziness, half reached primary completion within 22 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 42. This study's planned 1 month is below that.

Counting every sponsor, half of 90 studies reached it within 20 months; a quarter within 8 and three quarters within 42.

How these figures are worked out, and which studies are left out of them.

Registered
Aug 25, 2026
First posted
Aug 27, 2026
StartActual
Aug 11, 2026
Primary completionEst.
Sep 16, 2026
CompletionEst.
Oct 10, 2026
Last update
Aug 27, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Aug 27, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07790874
Responsible party
Sponsor
First posted
Aug 27, 2026
Start date
Aug 11, 2026
Primary completion
Sep 16, 2026 (estimated)
Completion
Oct 10, 2026 (estimated)
Last update
Aug 27, 2026

Study contacts

Imran Amjad, PhD
Contact
imran.amjad@riphah.edu.pk
03324390125
Saba Rafiq, PhD
principal investigator · Riphah International University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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