An interventional study of Cervical Epidural Steroid Injection and Cervical Stabilization Exercise Program in Chronic Neck Pain and Cervical Radiculopathy, sponsored by Alİ Eman, MD. Recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 55 Years. Per ClinicalTrials.gov, last updated 2026-09-08.
Sponsored by Alİ Eman, MD · Not applicable, Interventional, and Treatment
Chronic neck pain can negatively affect daily activities, work ability, and quality of life. Cervical epidural block is commonly used to reduce pain and inflammation, while exercise and physical therapy aim to improve muscle strength, endurance, movement control, and physical function. However, there is limited evidence comparing cervical epidural block alone with its combined use with exercise or physical therapy.
This study aims to compare the effects of three treatment approaches in patients with chronic neck pain associated with cervical disc pathology or degenerative changes. Participants will receive cervical epidural block alone, cervical epidural block combined with cervical stabilization exercises, or cervical epidural block combined with physical therapy. Pain intensity, neck-related disability, and quality of life will be evaluated before treatment and at 1, 3, and 6 months after treatment using the Numeric Rating Scale, Neck Disability Index, and 12-Item Short Form Health Survey. The study will determine whether adding exercise or physical therapy to cervical epidural block provides additional clinical and functional benefits.
Chronic neck pain is a common musculoskeletal condition associated with limitations in daily activities, reduced work capacity, and impaired quality of life. Cervical disc degeneration and herniation are among the structural conditions that may contribute to persistent neck pain. Although education, medications, exercise, and physical therapy are commonly used as conservative treatments, symptoms may persist in some patients. Cervical epidural block is used in clinical practice to reduce pain and inflammation associated with cervical disc pathology.
Exercise and physical therapy may complement the effects of cervical epidural block by improving cervical muscle strength, endurance, neuromuscular control, and physical function. However, evidence directly comparing cervical epidural block alone with its combined use with cervical stabilization exercises or physical therapy is limited. This three-group study will compare the clinical and functional effects of these treatment approaches in patients with chronic neck pain associated with cervical disc pathology or degenerative changes. The findings may help determine whether adding exercise or physical therapy to cervical epidural block provides additional benefits and may guide treatment planning for patients with chronic neck pain.
483 studies on the registry are indexed under Radiculopathy; 145 are open to participants now.
This study's planned enrollment of 60 is close to the median of 60 across 373 interventional studies indexed under Radiculopathy.
Browse Radiculopathy studies →This is the only study on the registry with Alİ Eman, MD as lead sponsor.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
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Cancer (malignancy)
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants in this arm receive cervical epidural steroid injection alone.
Procedure: Cervical Epidural Steroid Injection
Participants in this arm receive cervical epidural steroid injection combined with a cervical stabilization exercise program.
Procedure: Cervical Epidural Steroid Injection · Behavioral: Cervical Stabilization Exercise Program
Participants in this arm receive cervical epidural steroid injection combined with a physical therapy program.
Procedure: Cervical Epidural Steroid Injection · Other: Physical Therapy Program
Participants receive a cervical epidural steroid injection for the treatment of chronic neck pain associated with cervical radiculopathy.
Participants perform a cervical stabilization exercise program in addition to cervical epidural steroid injection.
Participants receive a physical therapy program in addition to cervical epidural steroid injection.
Change in Pain Intensity Assessed by the Numeric Rating Scale
Pain intensity will be assessed using the Numeric Rating Scale (NRS). Participants rate their pain on an 11-point scale ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Lower scores indicate lower pain intensity. Changes from baseline will be compared among the three treatment groups.
Time frame: Baseline and 1, 3, and 6 months after treatment
Change in Neck-Related Disability Assessed by the Neck Disability Index
Neck-related disability will be assessed using the Neck Disability Index (NDI). The questionnaire consists of 10 items, each scored from 0 to 5, with a total score ranging from 0 to 50. Higher scores indicate greater neck-related disability. Changes from baseline will be compared among the three treatment groups.
Time frame: Baseline and 1, 3, and 6 months after treatment
Change in Health-Related Quality of Life Assessed by the 12-Item Short Form Health Survey
Health-related quality of life will be assessed using the 12-Item Short Form Health Survey (SF-12). The questionnaire provides Physical Component Summary and Mental Component Summary scores. Higher scores indicate better health-related quality of life. Changes from baseline will be compared among the three treatment groups.
Time frame: Baseline and 1, 3, and 6 months after treatment
Plan to share: No
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