An observational study in Postoperative Troponin Elevation and Intraoperative Perfusion, sponsored by Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital. Not yet recruiting at 1 site in Turkey (Türkiye). Open to participants aged 65 Years and older. Per ClinicalTrials.gov, last updated 2026-09-16.
Sponsored by Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital · Observational
This prospective observational study aims to evaluate the association between intraoperative perfusion variability and postoperative troponin elevation in geriatric patients undergoing major oncologic surgery. Intraoperative hemodynamic and perfusion-related parameters will be recorded, and postoperative troponin levels will be assessed to investigate whether intraoperative perfusion changes are associated with myocardial injury. Troponin measurements will be obtained preoperatively and at 24 hours after surgery
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital is the lead sponsor of 75 studies on the registry; 18 are open to participants now.
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Geriatric patients aged 65 years or older undergoing major abdominal oncologic surgery who meet the predefined eligibility criteria and have preoperative and 24-hour postoperative troponin measurements. Intraoperative hemodynamic and perfusion parameters, including PI, PVI, and cerebral oxygen saturation measured by NIRS, will be monitored throughout surgery and recorded at 15-minute intervals.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Geriatric patients undergoing elective major oncolojic surgery will be prospectively observed.Intraoperative hemodynamic and perfusion-related parameters will be recorded, and serum troponin levels will be measured preoperatively and 24 hours after surgery to evaluate the association between intraoperative perfusion variability and postoperative troponin elevation.
Change in Serum Troponin Concentration From Preoperative Baseline to 24 Hours After Surgery
Postoperative troponin elevation will be assessed by comparing serum troponin levels measured preoperatively and 24 hours after surgery. Its association with intraoperative perfusion variability will be evaluated.
Time frame: Preoperatively and 24 hours after surgery
Association Between Intraoperative Perfusion Index and Postoperative Troponin Elevation
Perfusion Index (PI) will be continuously monitored intraoperatively and recorded at 15-minute intervals. The association between intraoperative PI values and postoperative troponin elevation at 24 hours after surgery will be evaluated.
Time frame: Intraoperative monitoring from the start to the end of surgery; troponin measured preoperatively and at 24 hours postoperatively
Association Between Intraoperative Pleth Variability Index and Postoperative Troponin Elevation
Pleth Variability Index (PVI) will be continuously monitored intraoperatively and recorded at 15-minute intervals. The association between intraoperative PVI values and postoperative troponin elevation at 24 hours after surgery will be evaluated.
Time frame: Intraoperative monitoring from the start to the end of surgery; troponin measured preoperatively and at 24 hours postoperatively.
Association Between Intraoperative Cerebral Oxygen Saturation and Postoperative Troponin Elevation
Cerebral oxygen saturation measured by near-infrared spectroscopy (NIRS) will be continuously monitored intraoperatively and recorded at 15-minute intervals. The association between intraoperative cerebral oxygen saturation values and postoperative troponin elevation at 24 hours after surgery will be evaluated.
Time frame: Intraoperative monitoring from the start to the end of surgery; troponin measured preoperatively and at 24 hours postoperatively.
Plan to share: No
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This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital