An interventional study of Cluster Training With Blood Flow Restriction and Cluster Training Alone in Athletic Performance and Exercise Training, sponsored by Saif Rasheed Ghanim. Completed at 1 site in Iraq. Open to participants aged 17 Years to 20 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-16.
Sponsored by Saif Rasheed Ghanim · Not applicable, Interventional, and Other
This study evaluated the effects of adding individualized blood flow restriction (BFR) to cluster resistance training on swimming performance, physical fitness, and selected circulating growth factors in competitive swimmers.
Forty competitive swimmers participated in a matched, non-randomized controlled intervention involving two groups (20 participants per group). The experimental group performed cluster resistance training combined with individualized BFR, whereas the control group completed the same training program without BFR.
The intervention lasted 10 weeks, comprising five supervised training sessions per week (50 sessions in total). Each 100-minute session included a 15-minute warm-up, 30 minutes of dry-land cluster resistance training, 50 minutes of swimming-specific training, and a 5-minute cool-down.
Dry-land resistance exercises were performed at 60-70% of one-repetition maximum (1RM). BFR pressure was individualized to 50% of arterial occlusion pressure (AOP) for the upper limbs and 60% for the lower limbs. Swimming training intensity was prescribed according to individual maximal heart rate (HRmax).
The primary outcome was the change in 200-m freestyle swimming performance time from baseline to the end of the 10-week intervention. Secondary outcomes included standing long jump performance, mean 50-m split time during a continuous maximal 150-m swim, cadence-controlled Burpee repetitions, and resting serum concentrations of fibroblast growth factor-2 (FGF-2) and vascular endothelial growth factor A (VEGF-A).
The study investigated whether individualized BFR combined with cluster resistance training was associated with greater improvements in swimming performance and physiological responses compared with cluster resistance training alone.
Blood flow restriction (BFR) training involves the application of pneumatic cuffs to the proximal regions of the limbs to partially restrict arterial inflow and venous return during exercise. Cluster resistance training incorporates brief recovery intervals between small groups of repetitions to reduce fatigue and maintain exercise performance.
This matched, non-randomized controlled study investigated the effects of combining individualized BFR with cluster resistance training on swimming performance, physical fitness, and circulating growth factors in competitive swimmers.
Forty competitive swimmers aged 17-20 years participated in the study. Participants were matched according to sex, baseline 200-m freestyle performance, and standing long jump distance and allocated to two parallel groups: an experimental group (n = 20) performing cluster resistance training with individualized BFR and a control group (n = 20) performing the same training program without BFR.
The intervention lasted 10 weeks, comprising five supervised training sessions per week (50 sessions in total). Each session lasted 100 minutes, consisting of a 15-minute warm-up, an 80-minute main training phase, and a 5-minute cool-down. The main phase included 30 minutes of dry-land cluster resistance training followed by 50 minutes of swimming-specific training.
Dry-land resistance exercises were prescribed at 60-70% of one-repetition maximum (1RM). The experimental group performed the resistance exercises with individualized BFR pressures corresponding to 50% of arterial occlusion pressure (AOP) for the upper limbs and 60% for the lower limbs. The control group performed the same exercises without BFR.
Swimming training intensity was prescribed relative to individually assessed maximal heart rate (HRmax). Weekly intensity targets progressed through 60%, 70%, 75%, 85%, 65%, 80%, 90%, 95%, 100%, and 80% of HRmax across the 10-week intervention. These percentages represented prescribed intensity targets rather than intensities maintained continuously throughout each session.
Swimming performance was assessed using a maximal 200-m freestyle test in a standardized 50-m swimming pool with electronic timing. Additional performance assessments included standing long jump distance, mean 50-m split time during a continuous maximal 150-m swim, and repetitions completed during a cadence-controlled Burpee test.
Resting serum concentrations of fibroblast growth factor-2 (FGF-2) and vascular endothelial growth factor A (VEGF-A) were assessed using enzyme-linked immunosorbent assays (ELISA). Post-intervention blood samples were collected under standardized fasting conditions 48 hours after the final training session.
The primary outcome was the change in 200-m freestyle performance time from baseline to Week 10. Secondary outcomes included changes in physical-performance measures and resting serum FGF-2 and VEGF-A concentrations.
The study evaluated whether adding individualized BFR to cluster resistance training was associated with greater improvements in swimming performance and selected physiological responses compared with cluster resistance training alone.
Saif Rasheed Ghanim is the lead sponsor of 2 studies on the registry; none are open to participants now.
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Competitive 200-m freestyle swimmers aged 17-20 years. At least 2 years of structured swimming training experience. Free from musculoskeletal injury for at least 6 months before enrollment. No previous regular experience with blood flow restriction training. Willing and able to complete the 8-week training intervention and all study assessments.
Exclusion Criteria:
History of cardiovascular, metabolic, thrombotic, or other vascular conditions that could contraindicate blood flow restriction exercise.
Current use of medications known to affect vascular tone or blood coagulation. Musculoskeletal injury or medical condition preventing participation in maximal swimming or dry-land training.
Attendance below 85% of the scheduled intervention sessions.
Participants in this arm completed an 8-week cluster-training program combined with blood flow restriction (BFR). Training was performed five sessions per week. Pneumatic cuffs were applied proximally to the upper arms and thighs during selected dry-land cluster exercises and intra-set recovery periods, and were deflated during the main inter-set recovery periods.
Behavioral: Cluster Training With Blood Flow Restriction
Participants in this arm completed the same 8-week cluster-training program and overall training schedule as the experimental group, but without blood flow restriction. Training was performed five sessions per week.
Behavioral: Cluster Training Alone
An 8-week cluster-training program performed five sessions per week, with blood flow restriction applied during selected dry-land cluster exercises using pneumatic cuffs positioned proximally on the upper arms and thighs.
An 8-week cluster-training program performed five sessions per week without blood flow restriction.
Change in 200-m Freestyle Performance Time
Performance was assessed during a maximal 200-m freestyle swim in a standard 50-m pool using an electronic timing system with a precision of 0.01 s. Lower values indicate faster performance. The primary outcome was the change in performance time from baseline to the end of the 10-week intervention.
Time frame: Baseline (Week 0) and post-intervention (Week 10)
Plan to share: No
No publications or documents are linked to this record.
Ran from Jan 2026 to primary completion in Apr 2026, 3 months.
Since we started tracking on Sep 25, 2026, the dates moved once, on Oct 16, 2026: primary completion Mar 2026 → Apr 2026 and completion Jun 2026 → Apr 2026.
Earlier changes are on the record history on ClinicalTrials.gov ↗
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Saif Rasheed Ghanim