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CompletedNCT07777692Updated Aug 20, 2026

Vestibular Rehabilitation Exercises to Improve Gait, Balance, and Dynamic Visual Acuity in Patients With Vestibular Hypofunction

An interventional study of Vestibular Rehabilitation Therapy and Conventional Physiotherapy in Vestibular Hypofunction, sponsored by University of Lahore. Completed at 1 site in Pakistan. Open to participants aged 39 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-08-20.

Sponsored by University of Lahore · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
58
Allocation
Randomized
Ages
39 Years to 60 Years
Sex
All
01

Study summary

## Brief Summary

Unilateral vestibular hypofunction (UVH) is a condition characterized by reduced or absent function of one vestibular system and commonly results in dizziness, impaired postural control, gait difficulties, reduced dynamic visual acuity, and increased risk of falls. These impairments can substantially affect functional independence and quality of life. Vestibular rehabilitation therapy (VRT) is an exercise-based physiotherapy approach designed to promote central vestibular compensation through gaze stabilization, habituation, balance, and gait training. However, the evidence comparing the additional benefits of VRT with conventional physiotherapy, particularly in the local population, remains limited. Therefore, this study was conducted to determine and compare the effects of VRT and conventional physiotherapy on balance, gait, dynamic visual acuity, and dizziness-related disability in patients with chronic unilateral vestibular hypofunction.

A single-blinded randomized controlled trial was conducted on 58 participants aged 38-60 years with chronic unilateral vestibular hypofunction. Participants were randomly allocated into an experimental group and a control group, with 29 participants in each group. The experimental group received conventional physiotherapy combined with vestibular-specific rehabilitation, including VOR x1/x2 gaze stabilization, postural stability exercises, and habituation exercises. The control group received conventional physiotherapy consisting of core strengthening and gait training without vestibular-specific interventions. Both groups received treatment twice weekly for eight weeks, with each session lasting approximately 45 minutes. Outcome measures included the Timed Up and Go (TUG) test for functional mobility, Dynamic Visual Acuity (DVA) for visual stability, Dizziness Handicap Inventory (DHI) for dizziness-related disability, and Tandem Romberg testing for balance.

The findings demonstrated greater improvements in the experimental group across the assessed outcomes. TUG performance improved, while DVA and DHI scores showed marked improvement, indicating better visual stability and reduced dizziness-related disability. Romberg performance also improved substantially, reflecting enhanced postural stability and balance control. In comparison, the control group demonstrated smaller or inconsistent changes, particularly in DVA, DHI, and functional mobility. Statistical analysis was performed using non-parametric tests because most study variables were not normally distributed. Within-group comparisons were conducted using the Wilcoxon Signed-Rank Test, while between-group comparisons were performed using the Mann-Whitney U Test.

The study concluded that vestibular rehabilitation therapy is an effective intervention for improving balance, dynamic visual acuity, and dizziness-related disability in patients with unilateral vestibular hypofunction. The experimental group showed greater improvements in postural stability, visual stability, and perceived disability than the conventional physiotherapy group. However, no significant between-group difference was observed for TUG, suggesting that conventional physiotherapy may provide adequate improvement in basic functional mobility. Overall, the findings support incorporating vestibular rehabilitation into physiotherapy management of UVH to enhance sensory integration and functional recovery.

The study recommends early initiation of VRT, individualized exercise programs, and emphasis on home exercises to improve adherence and long-term outcomes. Future research should involve larger samples, multicenter studies, longer follow-up periods, and investigation of optimal exercise dosage and progression.

02

Conditions studied

  • Vestibular Hypofunction
03

Who can participate

Ages eligible
39 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

    • Age group of 39 - 60 was included in this study. (Grill et al., 2018)

      • Both male and female gender
      • Participants who have chronic condition (past 3 months) (Karabulut et al., 2023)
      • Diagnostic tests:
      • Tandem Romberg with eyes closed (\<30s)
      • Timed Up and Go (6 s) - Single leg stance with eyes closed
      • Timed Up and Go (7 s) Tandem Romberg with eyes closed
      • Timed Up and Go (8 s) Standing on foam with eyes closed (Salah et al., 2020)
      • Referred patient were confirmed by dynamic visual acuity test (DVAT)(Vital et al., 2010).

Exclusion criteria

Exclusion Criteria:

    • Dizziness associated with other neurological conditions (e.g Stroke, diabetic neuropathy) (Yang et al., 2024)

      • Bilateral vestibular hypofunction was excluded (Karabulut et al., 2023)
      • Patients diagnosed with other neurological conditions that may affect balance, gait, or vestibular function, such as multiple sclerosis, Parkinson's disease, cerebellar ataxia etc. (Hall et al., 2022)
      • Participants with cognitive dysfunction (Hall et al., 2022)
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
58 participants (actual)

Study arms

  • Experimental
    Vestibular Rehabilitation Therapy + Conventional Physiotherapy

    Participants in this group will receive vestibular rehabilitation therapy in addition to conventional physiotherapy for 8 weeks. Vestibular rehabilitation will include gaze stabilization exercises (VOR x1/x2), habituation exercises, and balance training. Treatment will be provided twice weekly, with each session lasting approximately 45 minutes.

    Behavioral: Vestibular Rehabilitation Therapy · Behavioral: Conventional Physiotherapy

  • Active comparator
    Conventional Physiotherapy

    Participants in this group will receive conventional physiotherapy alone for 8 weeks. The conventional physiotherapy program will include core strengthening and gait training without the vestibular-specific rehabilitation program.

    Behavioral: Vestibular Rehabilitation Therapy · Behavioral: Conventional Physiotherapy

Interventions

  • BehavioralVestibular Rehabilitation Therapy

    Vestibular rehabilitation therapy consisting of gaze stabilization exercises (VOR x1/x2), habituation exercises, and balance training, administered in addition to conventional physiotherapy. The intervention will be provided twice weekly for 8 weeks, with each session lasting approximately 45 minutes.

  • BehavioralConventional Physiotherapy

    Conventional physiotherapy consisting of core strengthening and gait training, administered for 8 weeks. Participants received treatment twice weekly.

05

What researchers measure

Primary outcomes

  1. Balance

    Time frame: 6 weeks

06

Study locations

1 site
  • 1-Km Defence Road, near Bhuptian Chowk, Lahore, Pakistan.
    Lahore, Punjab Province 54000, Pakistan
07

Registry details

Key details

Study ID
NCT07777692
Lead sponsor
University of Lahore
Responsible party
Sadaf Anjum (sadaf anjum, University of Lahore) — Principal investigator
First posted
Aug 20, 2026
Start date
Apr 15, 2026
Primary completion
Jul 20, 2026
Completion
Jul 20, 2026
Last update
Aug 20, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
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