ClinicalTrials.gg
RecruitingNCT07767227Updated Aug 17, 2026

Blood and Cystic Fluid From Patients Undergoing Surgery for Worrisome Pancreatic Cysts

An observational study in Pancreatic Cyst, sponsored by Translational Genomics Research Institute. Recruiting at 2 sites in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-08-17.

Sponsored by Translational Genomics Research Institute · Observational

From the registry’s dates

  • Started Feb 2025; still recruiting 1 year 9 months later.
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
30
Ages
18 Years and older
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 54 studies in Pancreatic Cyst with a site in United States — 20 open to participants now, 23 under way, 1 of them phase 3. Pancreatic Cyst · United States.

Planned enrollment
28th of 32
30 · median 300
Started
2025
with 1 other
Observational
32 of 54
12 open now
Primary completion
2027-12
later than 10 of 22 live
Registered
54th of 54
by date

Among the 54 studies in Pancreatic Cyst with a site in United States, this one is the 28th largest by planned enrollment of the 32 observational ones that give a count, is one of 2 that started in 2025, is one of 32 observational ones, reaches primary completion later than 10 of the 22 other live ones, and was the 54th registered.

Pancreatic Cyst

97 studies on the registry are indexed under Pancreatic Cyst; 37 are open to participants now.

Browse Pancreatic Cyst studies →

Open to participants now

20 of the 54 studies in Pancreatic Cyst with a site in United States are open now. Recruiting first, the newest first:

14 more — sign in →

All 20 open studies →

A study can be open while its sites in United States have not opened yet or have stopped. Only those recruiting at a site in United States →

Who these studies take

Of the 33 Pancreatic Cyst studies recruiting now, 25 (76%) set no upper age limit and 0 (0%) stop at 75 or younger; 2 take children under 18; 7 take healthy volunteers.

This study: 18 Years and older · all sexes · no healthy volunteers.

The full table on the hub →

This tab as a report to print or save as PDF → With an account.

Was this useful?
Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 54 studies in Pancreatic Cyst with a site in United States, or all of them as a file.
02

Study summary

The goal of this study is to collect biospecimens (blood and cystic fluid) and data from participants who have a pancreatic cyst that requires surgical resection. The blood and fluid samples will be analyzed for research into DNA, RNA, and proteins.

03

Conditions studied

  • Pancreatic Cyst

Browse trials for

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Participants will, primarily, be patients of the clinical Investigators at HOAG and Piedmont Healthcare hospitals who are or will be scheduled for surgical resection of their worrisome pancreatic cyst as part of their clinically indicated care.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Voluntarily agree to participate by giving written prior to any study-specific procedures.
  • Subject at least 18 years of age and able to provide consent. Subject is willing and able to comply with requirements of the protocol.
  • Radiologically documented cyst of the pancreas for which surgical removal is clinically indicated.
  • Patient will be undergoing a surgical resection of their pancreatic cystic neoplasm.

Exclusion criteria

Exclusion Criteria:

  • Patient who is pregnant at the time of study enrollment and sample collection.
  • Patient will not be undergoing clinically indicated surgery for a pancreatic cystic neoplasm.
  • Patient is unwilling or unable to provide or comply with study procedures.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
30 participants (estimated)
Patient registry
No
Biospecimen retention
Samples with dna

Groups and cohorts

  • Pancreatic cyst

    Patients who are or will be scheduled for surgical resection of their worrisome pancreatic cyst as part of their clinically indicated care.

06

What researchers measure

Primary outcomes

  1. Characterize the miRNA and protein signatures in exosomes derived from blood and cyst fluids in patients with worrisome cystic pancreatic tumors

    Time frame: At enrollment

07

Study locations

2 of 2 sites recruiting
08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Feb 2025 (actual). Primary completion is estimated for Dec 2027, 34 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Aug 11, 2026
First posted
Aug 17, 2026
StartActual
Feb 3, 2025
Primary completionEst.
Dec 2027
CompletionEst.
Mar 2028
Last update
Aug 17, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Aug 17, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07767227
Lead sponsor
Translational Genomics Research Institute
Collaborators
Hoag Memorial Hospital Presbyterian, City of Hope National Medical Center, Piedmont Healthcare
Responsible party
Sponsor
First posted
Aug 17, 2026
Start date
Feb 3, 2025
Primary completion
Dec 2027 (estimated)
Completion
Mar 2028 (estimated)
Last update
Aug 17, 2026

Study contacts

Michael Demeure, MD
Contact
clinicalresearch@hoag.org
949-764-4577
Michael Demeure, MD
principal investigator · Hoag Family Cancer Institute

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Interested in this study?

Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.

Contact study team

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion