An interventional study of magnesium-based sleep & recovery supplement and Placebo Supplementation in Athletes and Healthy, sponsored by University of Exeter. Not yet recruiting. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-10.
Sponsored by University of Exeter · Not applicable, Interventional, and Treatment
The goal of this clinical trial (randomised crossover study) is to learn if a multi-component sleep and exercise recovery supplement can improve sleep quality and enhance recovery following exercise in healthy, recreationally active adults aged 18-40.
The main questions it aims to answer are:
Researchers will compare the supplement to a placebo (a look-alike tablet with no active ingredients) to see if the supplement improves exercise recovery and sleep quality. In this crossover design, all participants will receive both the supplement and the placebo in separate 2-week periods, with a 2-week washout period in between.
Participants will:
University of Exeter is the lead sponsor of 140 studies on the registry; 25 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Not have any injuries that would affect performance
Supplementation of a magnesium-based sleep \& recovery supplement (2g/day for 2-weeks)
Dietary Supplement: magnesium-based sleep & recovery supplement
Supplementation of placebo (2g/day for 2-weeks)
Dietary Supplement: Placebo Supplementation
magnesium-based sleep \& recovery supplement (2g/day for 2-weeks)
Placebo Supplementation (2g/day for 2-weeks)
Changes in total work done
Changes in total work done as measured by the Biodex
Time frame: Following each 2-week supplementation period of either supplement
Changes in work done (Flexion)
Changes in work done (Flexion) as measured by the Biodex
Time frame: Following each 2-week supplementation period of either supplement
Changes in work done (Extension)
Changes in work done (Extension) as measured by the Biodex
Time frame: Following each 2-week supplementation period of either supplement
Changes in Single Leg jump height
Changes in Single Leg jump height (m)
Time frame: Before and Immediately After Muscle Damaging Protocol at the End of Each 2-Week Supplementation Period
Changes in Single Leg Jump hang time
Changes in Single Leg Jump hang time (s)
Time frame: Before and Immediately After Muscle Damaging Protocol at the End of Each 2-Week Supplementation Period
Changes in sleep quality
Changes in sleep quality as measured by the Groningen Sleep Quality questionnaire where a lower score indicates better sleep quality.
Time frame: Following each 2-week supplementation period of either supplement.
Changes in perceived muscle soreness (Pain pressure threshold)
Changes in perceived muscle soreness (Pain pressure threshold in Newtons) as measured by the muscle algometer where a higher score means a better outcome
Time frame: Following each 2-week supplementation period of either supplement and 24hr and 48hr following the muscle damaging protocol.
Change in Self-Reported Readiness to Train Score (5-Point Likert Scale)
Change in perceived readiness to train or compete assessed using a self-reported 5-point Likert scale, where 1 = not at all ready (extremely fatigued/sore) and 5 = completely ready (fresh, no limitations)
Time frame: Following each 2-week supplementation period of either supplement and 24hr and 48hr following the muscle damaging protocol
Changes in Sleep Quality
Changes in Sleep Quality as measured by the Consensus Sleep Diary.
Time frame: Following each 2-week supplementation period of either supplement.
Change in perceived recovery status (10-Point Likert Scale)
Change in perceived readiness to train or compete assessed using a self-reported 10-point Likert scale, where 0 = very poorly recovered and 10 = fully recovered
Time frame: Following each 2-week supplementation period of either supplement and 24hr and 48hr following the muscle damaging protocol
Change in perceived overall muscle soreness (10-Point Likert Scale)
Change in perceived readiness to train or compete assessed using a self-reported 10-point Likert scale, where 0 = no soreness and 10 = worse soreness imaginable
Time frame: Following each 2-week supplementation period of either supplement and 24hr and 48hr following the muscle damaging protocol
No study locations are listed for this record.
Plan to share: Yes
Supporting information: Study protocol, Statistical analysis plan, Informed consent form
No publications or documents are linked to this record.
Start is estimated for Aug 2026; primary completion for Oct 2026, 2 months later.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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