ClinicalTrials.gg
Not yet recruitingNCT07755527HOPEUpdated Sep 23, 2026

Healing After Injury to Reduce Opioid Use and Pain Through Preventive Engagement - Open Trial

An interventional study of Psychological Intervention in Pain and Opioid Use, sponsored by Henry Ford Health System. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-23.

Sponsored by Henry Ford Health System · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
10
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Study summary

The goal of this project is to refine the adaptive psychological intervention and assess initial feasibility and acceptability. Results will be used to inform a pilot randomized trial.

02

Conditions studied

  • Pain
  • Opioid Use

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03

In context

Pain

10,054 studies on the registry are indexed under Pain; 1,649 are open to participants now.

This study's planned enrollment of 10 is below the median of 66 across 8,493 interventional studies indexed under Pain.

Browse Pain studies →

Lead sponsor

Henry Ford Health System is the lead sponsor of 303 studies on the registry; 50 are open to participants now.

Of its 37 completed or terminated interventional studies of FDA-regulated products, 26 (70%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Admitted to Henry Ford Hospital
  • Has an acute musculoskeletal injury
  • Prescribed opioids during the admission

Exclusion criteria

Exclusion Criteria:

  • Under age 18
  • Cognitive impairment (i.e., diagnosis of delirium, dementia, or traumatic brain injury/Glasgow Coma Scale less than 13)
  • Chronic pain condition (i.e., pain most of the day, nearly every day for the past 3 months or longer)
  • Taking opioids 30 days or more prior to this hospitalization
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
10 participants (estimated)

Study arms

  • Experimental
    Psychological Intervention

    Participants will receive a computerized brief intervention followed by four weekly psychological treatment sessions.

    Behavioral: Psychological Intervention

Interventions

  • BehavioralPsychological Intervention

    Participants will complete a computerized brief intervention (education about long-term opioid use and a mindfulness strategy) followed by four psychotherapy sessions composed of education, mindfulness, and acceptance-based strategies.

06

What researchers measure

Primary outcomes

  1. Acceptability of the intervention

    Percentage of participants that agreed/strongly agreed with items on the acceptability of intervention measure (AIM), intervention appropriateness measure (IAM), and feasibility of intervention measure (FIM).

    Time frame: Post-intervention (40-day follow-up)

Secondary outcomes

  1. Treatment adherence

    Percentage of participants that attended at least 3 of 4 sessions

    Time frame: Post-intervention (40-day follow-up)

  2. Study adherence

    Percentage of participants that completed the post-intervention assessment

    Time frame: Post-intervention (40-day follow-up)

07

Study locations

No study locations are listed for this record.

08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Sep 2026; primary completion for Mar 2027, 6 months later.

Of 3,731 non-industry interventional studies with no phase under Pain, half reached primary completion within 10 months of starting (the median), counting those still running; a quarter within 4 and three quarters within 23. This study's planned 6 months is below that.

Counting every sponsor, half of 3,830 studies reached it within 10 months; a quarter within 4 and three quarters within 23.

How these figures are worked out, and which studies are left out of them.

Registered
Aug 5, 2026
First posted
Aug 10, 2026
StartEst.
Sep 2026
Primary completionEst.
Mar 2027
CompletionEst.
Mar 2027
Last update
Sep 23, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 23, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07755527
Responsible party
Lisa Matero (Associate Scientist, Henry Ford Health System) — Principal investigator
First posted
Aug 10, 2026
Start date
Sep 2026 (estimated)
Primary completion
Mar 2027 (estimated)
Completion
Mar 2027 (estimated)
Last update
Sep 23, 2026

Study contacts

Lisa Matero, PhD
Contact
LMatero1@hfhs.org
313-874-5454

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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