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Not yet recruitingNCT07746076Updated Aug 4, 2026

A Clinical Trial to Evaluate the Effects of Naila's Collagen Marine Plus Food Supplement on Skin Hydration, Elasticity, Fine Lines and Wrinkles, and Hair and Nail Health

An interventional study of Naila's Collagen Marine Plus Food Supplement in Skin Aging, Skin Hydration and Skin Elasticity, sponsored by Gulf Bird. Not yet recruiting. Open to participants aged 30 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-04.

Sponsored by Gulf Bird · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Not applicable
Ages
30 Years to 60 Years
Sex
All
01

Study summary

This is a single-group, open-label, virtual (decentralized) clinical trial evaluating the effects of Naila's Collagen Marine Plus Food Supplement on skin hydration, elasticity, firmness, fine lines and wrinkles, and hair and nail health over 12 weeks. Forty healthy adults aged 40-60 years with self-reported mature skin showing early signs of aging will take one sachet of the supplement daily and complete questionnaires at Baseline, Week 4, Week 8, and Week 12.

Participants will also submit standardized facial and hair photographs at Baseline and Week 12 for evaluation by a board-certified dermatologist. The primary objectives are to assess changes in skin aging parameters and hair health. Secondary objectives include evaluation of nail health, hair shedding and density, participant-reported satisfaction, and product safety and tolerability.

02

Conditions studied

  • Skin Aging
  • Skin Hydration
  • Skin Elasticity
  • Fine Lines and Wrinkles
  • Hair Health
  • Nail Health
03

In context

Lead sponsor

This is the only study on the registry with Gulf Bird as lead sponsor.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
30 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Healthy adults aged 40-60 years at the time of enrollment.
  • Self-reported visible signs of skin aging, including at least one of the following: fine lines, wrinkles, reduced skin firmness or elasticity, or skin dryness.
  • Self-reports hair shedding and a desire to improve hair health.
  • Willing to take one sachet of the study product daily for 12 weeks as directed.
  • Willing to avoid taking any other collagen-containing dietary supplements for the duration of the study.
  • Willing to maintain current diet, skincare routine, sleep patterns, and physical activity levels for the duration of the trial.
  • Willing and able to submit standardized facial and hair photographs at Baseline and Week 12.
  • Has access to a smartphone or digital camera capable of producing photographs.
  • Resides in the United States.
  • Willing to follow the study protocol and complete all required questionnaires.

Exclusion criteria

Exclusion Criteria:

  • Known allergy or sensitivity to fish, marine-derived products, or any of the study product ingredients (marine collagen, hyaluronic acid, ascorbic acid, biotin).
  • Previous diagnosis of a hair loss condition such as alopecia areata, androgenetic alopecia, or telogen effluvium.
  • Currently taking any collagen-containing dietary supplements, or planning to start taking any collagen supplements in the next 12 weeks.
  • Any current uncontrolled chronic medical condition that would prevent the participant from safely completing the study protocol.
  • History of a diagnosed dermatological condition that significantly affects facial skin appearance (e.g., severe eczema, psoriasis, rosacea, or active acne) and could confound assessment of skin aging outcomes.
  • Use of prescription retinoids, injectable dermal fillers, botulinum toxin, chemical peels, laser skin treatments, or other professional aesthetic procedures on the face within 3 months prior to enrollment or planned during the study period.
  • Currently pregnant, breastfeeding, or planning to become pregnant during the study period.
  • Currently participating in another research study or planning to participate in another study during this study's duration.
  • Any condition that, in the judgment of the investigator, would make the participant unsuitable for inclusion in the study.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
40 participants (estimated)

Study arms

  • Experimental
    Naila's Collagen Marine Plus Food Supplement

    Dietary Supplement: Naila's Collagen Marine Plus Food Supplement

Interventions

  • Dietary supplementNaila's Collagen Marine Plus Food Supplement

    All 40 participants receive Naila's Collagen Marine Plus Food Supplement (one sachet daily, dissolved in approximately 200 mL of water, taken once daily in the morning) for 12 weeks.

06

What researchers measure

Primary outcomes

  1. Change in Self-Reported Skin Hydration

    Mean change from Baseline in self-reported skin hydration assessed via self-reported questionnaire

    Time frame: Baseline to Week 12

  2. Change in Self-Reported Skin Elasticity

    Mean change from Baseline in self-reported skin elasticity assessed via self-reported questionnaire

    Time frame: Baseline to Week 12

  3. Change in Self-Reported Skin Firmness

    Mean change from Baseline in self-reported skin firmness assessed via self-reported questionnaire

    Time frame: Baseline to Week 12

  4. Change in Self-Reported Fine Lines and Wrinkles

    Mean change from Baseline in self-reported appearance of fine lines and wrinkles assessed via self-reported questionnaire

    Time frame: Baseline to Week 12

  5. Change in Dermatologist-Graded Fine Line and Wrinkle Severity

    Mean change from Baseline in fine line and wrinkle severity assessed by dermatologist review of standardized facial photographs

    Time frame: Baseline to Week 12

  6. Change in Dermatologist-Graded Skin Firmness

    Mean change from Baseline in skin firmness assessed by dermatologist review of standardized facial photographs

    Time frame: Baseline to Week 12

  7. Change in Dermatologist-Graded Overall Skin Quality

    Mean change from Baseline in overall skin quality assessed by dermatologist review of standardized facial photographs

    Time frame: Baseline to Week 12

  8. Change in Dermatologist-Graded Hair Parameters

    Mean change from Baseline in hair health parameters assessed by dermatologist review of standardized hair photographs

    Time frame: Baseline to Week 12

Secondary outcomes

  1. Change in Self-Reported Nail Strength

    Mean change from Baseline in self-reported nail strength assessed via self-reported questionnaire

    Time frame: Baseline to Week 12

  2. Change in Self-Reported Nail Brittleness

    Mean change from Baseline in self-reported nail brittleness assessed via self-reported questionnaire

    Time frame: Baseline to Week 12

  3. Change in Self-Reported Nail Growth Rate

    Mean change from Baseline in self-reported nail growth rate assessed via self-reported questionnaire

    Time frame: Baseline to Week 12

  4. Change in Self-Reported Overall Nail Appearance

    Mean change from Baseline in self-reported overall nail appearance assessed via self-reported questionnaire

    Time frame: Baseline to Week 12

  5. Change in Self-Reported Hair Shedding

    Mean change from Baseline in self-reported hair shedding assessed via self-reported questionnaire

    Time frame: Baseline to Week 12

  6. Change in Self-Reported Hair Thickness and Density

    Mean change from Baseline in self-reported hair thickness and density assessed via self-reported questionnaire

    Time frame: Baseline to Week 12

  7. Participant-Reported Product Satisfaction and Perceived Global Improvement

    Participant-reported satisfaction and perceived global improvement assessed via self-reported questionnaire at Week 12

    Time frame: Week 12

  8. Incidence of Adverse Events

    Number and severity of adverse events reported by participants throughout the 12-week study period, assessed via study questionnaires and reviewed by the study team

    Time frame: Baseline through Week 12

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 4, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07746076
Lead sponsor
Gulf Bird
Collaborators
Citruslabs
Responsible party
Sponsor
First posted
Aug 4, 2026
Start date
Aug 2026 (estimated)
Primary completion
Nov 2026 (estimated)
Completion
Nov 2026 (estimated)
Last update
Aug 4, 2026

Study contacts

Patrick Renner
Contact
hello@citruslabs.com
4242450284

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.

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