ClinicalTrials.gg
RecruitingNCT07739238Updated Jul 31, 2026

THE EFFECTS OF DIFFERENT BREATHING EXERCISES ON RESPIRATORY PARAMETERS AND HEART RATE VARIABILITY

An interventional study of breathing exercises in Healthy, sponsored by Bandırma Onyedi Eylül University. Recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 30 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-31.

Sponsored by Bandırma Onyedi Eylül University · Not applicable, Interventional, and Prevention

From the registry’s dates

  • Primary completion was expected by Aug 2026, 3 months ago, but the record still lists the study as recruiting.
  • Started Feb 2024; still recruiting 2 years 9 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
44
Allocation
Randomized
Ages
18 Years to 30 Years
Sex
All
01

Study summary

Breathing is a vital process that occurs automatically, but it can also be voluntarily controlled to achieve specific goals, especially preventive and therapeutic ones. Slow breathing has been reported to have many physical and mental health benefits. The activation of the sympathetic system during inhalation and the increase in heart rate, as well as the activation of the parasympathetic system during exhalation and the resulting decrease in heart rate variability, can be affected by breathing exercises. The physiological effects associated with breathing exercises vary depending on the type of exercise performed. Therefore, investigating and comparing the clinical effects and contributions of different breathing exercises will shed light on which breathing exercises should be preferred in different situations.

This study aims to examine the effects of diaphragmatic breathing, square breathing technique, alternative nostril breathing exercises, and diaphragmatic breathing exercises on respiratory function parameters and heart rate variability, and to compare these different breathing exercises. Healthy individuals aged 18-30 years from the Department of Physiotherapy and Rehabilitation at Bandırma Onyedi Eylül University will be invited to participate in the study. For the study, a sample size of 40 was determined in the "G*Power" analysis system with a moderate effect size according to Cohen, a statistical significance threshold of 5% (alpha level = 0.05), and 80% power (Cohen, J.; 2013), allowing for evaluation of the four groups before the training program, immediately after the first session (acute effect), and after the training program (6 weeks). To account for potential dropouts, the target is to reach 44 participants, which is 10% more than the calculated sample size. Power calculations will be performed during the study process, and revisions regarding sample size will be made if necessary. Participants will be randomized using a sealed envelope randomization method. Respiratory function tests (FVC-FEV1- FEV1/FVC- FEF- PEF) will be performed using a COSMED Pony FX portable spirometer to evaluate participants' respiratory functions. Heart rate variability will be assessed by taking a 5-minute measurement using a Polar H10 device. Four different breathing exercise groups will be created, and participants will undergo diaphragmatic breathing exercises, square breathing technique exercises, alternative nostril breathing exercises, and dynamic neuromuscular stabilization-based breathing exercises for 6 weeks, with sessions lasting 20 minutes, four times a week. The initial session will be conducted face-to-face, while subsequent sessions will be conducted online (via zoom/video calls/Google Meet, etc.). Assessments will be conducted three times: at baseline, immediately after the first session (acute effect), and after the 6-week training program, and will be performed face-to-face.

02

Conditions studied

  • Healthy
03

In context

Lead sponsor

Bandırma Onyedi Eylül University is the lead sponsor of 70 studies on the registry; 19 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 30 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Eligibility criteria

Inclusion Criteria:

  • Inclusion Criteria:

    • Individuals willing to participate in the study
    • Individuals aged between 18 and 30 years
    • Individuals without a history of regular sports or physical activity habits

Exclusion Criteria:

  • Immobilized individuals
  • Athletes
  • Individuals with respiratory, cardiovascular, or renal system diseases
  • Individuals using medication for respiratory, cardiovascular, or renal system problems
  • Individuals who have undergone any surgery in the last 6 months
  • Individuals with neurological, systemic, or musculoskeletal disorders
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
44 participants (estimated)

Study arms

  • Experimental
    diaphragmatic breathing exercises

    diaphragmatic breathing exercises

    Other: breathing exercises

  • Experimental
    square breathing technique exercises

    Other: breathing exercises

  • Experimental
    alternative nostril breathing exercises

    Other: breathing exercises

  • Experimental
    dynamic neuromuscular stabilization-based breathing exercises

    Other: breathing exercises

Interventions

  • Otherbreathing exercises

    diaphragmatic breathing exercises, square breathing technique exercises, alternative nostril breathing exercises, and dynamic neuromuscular stabilization-based breathing exercises

06

What researchers measure

Primary outcomes

  1. Heart Rate Variability

    Heart Rate Variability

    Time frame: day 1/ acute (after the first session-in an hour)/six week

  2. respiratory parameters

    FEV

    Time frame: day 1/ acute (after the first session-in an hour)/six week

  3. respiratory parameters

    FEV1

    Time frame: day 1/ acute (after the first session-in an hour)/six week

  4. respiratory parameters

    FVC

    Time frame: day 1/ acute (after the first session-in an hour)/six week

07

Study locations

1 of 1 sites recruiting
  • Bandirma Onyedi Eylül University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation
    Balıkesir, In the USA Or Canada, Please Select... 10250, Turkey (Türkiye)
    Recruiting
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 31, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07739238
Lead sponsor
Bandırma Onyedi Eylül University
Responsible party
Esra KESKİN (Assisstant Professor, Bandırma Onyedi Eylül University) — Principal investigator
First posted
Jul 31, 2026
Start date
Feb 1, 2024
Primary completion
Aug 2026 (estimated)
Completion
Sep 2026 (estimated)
Last update
Jul 31, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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