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CompletedNCT07728331Updated Jul 27, 2026

Ultrasound-guided Combined Perineural and Intramuscular Dextrose Injection for Management of Refractory Bell's Palsy

A Phase 4 interventional study of Ultrasound-guided combined perineural and intramuscular dextrose injection. in Bell Palsy, sponsored by Al-Azhar University. Completed at 1 site in Egypt. Open to participants aged Up to 18 Years. Per ClinicalTrials.gov, last updated 2026-07-27.

Sponsored by Al-Azhar University · Phase 4, Interventional, and Treatment

From the registry’s dates

  • Registered 9 months after the study started (first participant enrolled Oct 2025, registered Jul 2026).
Phase
Phase 4
Study type
Interventional
Enrollment
30
Allocation
Not applicable
Ages
Up to 18 Years
Sex
All
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Study summary

Bell's palsy (BP) is characterized by idiopathic acute weakness of the facial muscles associated with compression of the facial nerve. The present prospective study sought to evaluate the clinical efficacy of ultrasound-guided combined perineural and intramuscular dextrose injection for management of refractory Bell's palsy. The study included 30 patients with Bell's palsy with House-Brackmann scale ≥ 3 who were refractory to standard medical treatment after 3 months of disease onset. They received ultrasound-guided combined perineural and intramuscular dextrose injection. Clinical outcome was assessed using the House-Brackmann scale.

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Conditions studied

  • Bell Palsy

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03

In context

Bell Palsy

120 studies on the registry are indexed under Bell Palsy; 38 are open to participants now.

This study's enrollment of 30 is below the median of 50 across 93 interventional studies indexed under Bell Palsy.

Browse Bell Palsy studies →

Lead sponsor

Al-Azhar University is the lead sponsor of 505 studies on the registry; 167 are open to participants now.

Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Up to 18 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

- The study included 30 patients with Bell's palsy diagnosed according to the recommendations of American Academy of Otolaryngology-Head and Neck Surgery Foundation

Exclusion criteria

Exclusion Criteria:

  • Patients were excluded if they were previously submitted to injection therapy or surgical intervention for management of Bell's palsy. They were also excluded if they had associated mental illness or advanced systemic conditions (e.g. uncontrolled diabetes, uncontrolled hypertension, malignant disease, immunocompromised conditions).
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Study design

Phase
Phase 4
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
30 participants (actual)

Study arms

  • Experimental
    Interventional arm

    Ultrasound-guided combined perineural and intramuscular dextrose injection.

    Procedure: Ultrasound-guided combined perineural and intramuscular dextrose injection.

Interventions

  • ProcedureUltrasound-guided combined perineural and intramuscular dextrose injection.

    Ultrasound-guided combined perineural and intramuscular dextrose injection.

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What researchers measure

Primary outcomes

  1. House Brackmann scale

    House Brackmann scale

    Time frame: 3 months

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Study locations

1 site
  • Al-Azhar University Hospital
    Cairo, 247883, Egypt
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 27, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07728331
Lead sponsor
Al-Azhar University
Responsible party
Seham A. Elazab (Dr, Al-Azhar University) — Principal investigator
First posted
Jul 27, 2026
Start date
Oct 10, 2025
Primary completion
Apr 1, 2026
Completion
Apr 1, 2026
Last update
Jul 27, 2026

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.

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