ClinicalTrials.gg
CompletedNCT07724379tetanusUpdated Jul 24, 2026

A Study of Tetanus Antibody of Healthy Adults

An observational study in Tetanus, sponsored by Peking University First Hospital. Completed at 1 site in China. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-24.

Sponsored by Peking University First Hospital · Observational

Study type
Observational
Model
Other
Time perspective
Prospective
Enrollment
2,009
Ages
18 Years and older
Sex
All
01

Study summary

The goal of this observational study is to learn about antibody level of tetanus of adults in high-income city of china. The main question it aims to answer is:

  1. Analysis of tetanus antibody distribution across different age groups
  2. Evaluation of the TQS method for determining antibody status
  3. Correlation between primary vaccination history and tetanus antibody concentrations Blood samples were voluntarily provided by adult healthy participants for tetanus antibody analysis over a continuous collection period of more than one year.
02

Conditions studied

  • Tetanus

Browse trials for

Keywords

  • Healthy Adults
  • Vaccination
  • Protective Efficacy
  • Observational Study
  • TQS
  • tetanus
03

In context

Tetanus

318 studies on the registry are indexed under Tetanus; 29 are open to participants now.

This study's enrollment of 2,009 is above the median of 645 across 35 observational studies indexed under Tetanus.

Browse Tetanus studies →

Lead sponsor

Peking University First Hospital is the lead sponsor of 390 studies on the registry; 186 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

This study will enroll healthy adults aged 18 years who reside in Beijing. Participants will be recruited voluntarily from the general population. Both males and females are eligible. Participants must be willing to provide a blood sample and complete a brief questionnaire regarding their vaccination history. Individuals with recent tetanus vaccination (within 5 years), acute illness, pregnancy, or immunosuppressive conditions will be excluded.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Voluntarily sign the form;
  • Be aged 18 years or older;
  • Be willing to provide a blood sample for biochemical testing

Exclusion criteria

Exclusion Criteria:

  • Receipt of immunoglobulin, blood, or blood products within 6 months prior to enrollment;
  • Refusal to provide tetanus vaccination history (including vaccination records, CDC vaccine administration registry, or subject's recall);
  • Individuals with recent tetanus vaccination (within 5 years), acute illness, pregnancy, or conditions will be excluded
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

Immunosuppression

A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.

Read whether the line is about a condition or about medicines, and which medicines and doses it means.

05

Study design

Observational model
Other
Time perspective
Prospective
Enrollment
2,009 participants (actual)
Target follow-up
6 Months
Patient registry
Yes
Biospecimen retention
Samples without dna

Groups and cohorts

  • age group

    20-29;30-39;40-49;50-59;≥60

  • gender group

    male; female

  • education background

    high school; bachelor; master; et al

  • primary vaccination

    ≥3 doses TTCV; \< 3 doses TTCV; unknown

  • last TTCV dose duration

    ≤5 year;5-10 year; \>10 year; unkown

06

What researchers measure

Primary outcomes

  1. Tetanus Antibody Level

    Single blood draw

    Time frame: Baseline (single blood draw at enrollment)

Secondary outcomes

  1. tetanus antibody level by TQS/mTQS method

    at baseline

    Time frame: Baseline (single blood draw at enrollment)

07

Study locations

1 site
  • Peking University First Hospital
    Beijing, Beijing Municipality 100034, China
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 24, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07724379
Responsible party
Liu Si (Chief Physician, Department Director, Peking University First Hospital) — Principal investigator
First posted
Jul 24, 2026
Start date
May 4, 2025
Primary completion
Mar 3, 2026
Completion
May 15, 2026
Last update
Jul 24, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion