An interventional study of Uncertainty Video and Uncertainty Normalization Video in Healthy, sponsored by Washington University School of Medicine. Not yet recruiting. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-20.
Sponsored by Washington University School of Medicine · Not applicable, Interventional, and Other
Few people realize that environmental pollution and some behaviors like physical activity and tobacco smoking can affect their health by "turning on" or "turning off" certain genes through a process called "epigenetic modification." This study will develop and test strategies for communicating about epigenetics that are understandable and that do not increase ethical, legal or social issues (ELSI).
1,573 studies on the registry are indexed under Behavior; 313 are open to participants now.
This study's planned enrollment of 1,000 is above the median of 120 across 1,197 interventional studies indexed under Behavior.
Browse Behavior studies →Washington University School of Medicine is the lead sponsor of 1,803 studies on the registry; 271 are open to participants now.
Of its 329 completed or terminated interventional studies of FDA-regulated products, 216 (66%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Identify as one of five racial/ethnic groups:
Exclusion Criteria:
Participants will watch a brief (\<5 minute) video about the concept of Epigenetics
Behavioral: Epigenetics Video
Participants will watch a brief (\<5 minute) video about the concept of Epigenetics as well as a brief (\<1 minute) video introducing uncertainty about epigenetics research.
Behavioral: Uncertainty Video · Behavioral: Epigenetics Video
Participants will watch a brief (\<5 minute) video about the concept of Epigenetics as well as a brief (\<1 minute) video normalizing uncertainty about epigenetics research.
Behavioral: Uncertainty Normalization Video · Behavioral: Epigenetics Video
Video introducing uncertainty about epigenetics research.
Video normalizing uncertainty about epigenetics research.
Video about the concept of epigenetics
Knowledge & understanding of epigenetics Information
Sum score of correct answers for 11 individual items. Scale ranges from 0 points to 11 points with higher scores indicating higher epigenetics knowledge.
Time frame: Baseline survey, after intervention video
Acceptability of epigenetics information
Three constructs including perceived benefits of epigenetic research (7 items, ranging from 1 to 5 with higher scores indicating higher perceived benefits), perceived drawbacks of epigenetic research (3 items, ranging from 1 to 5 with higher scores indicating higher perceived drawbacks), and acceptance of using epigenetic research in medical support (3 items, ranging from 1 to 5 with higher scores indicating higher acceptance of using epigenetic research in medical support).
Time frame: Baseline survey, after intervention video
Perceptions of epigenetic information
6 item scale where scores range from 1 to 5, with higher scores indicating greater perceptions of epigenetic information.
Time frame: Baseline survey, after intervention video
No study locations are listed for this record.
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: Yes
This study is not yet recruiting, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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