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Enrolling by invitationNCT07704151Updated Jul 15, 2026

Custom-made Zirconia Crowns Versus Prefabricated Zirconia Crowns in Young Permanent Molars

An interventional study of Prefabricated Zirconia Crown and Custom-made Zirconia Crowns in Zirconia Crowns, sponsored by Jordan University of Science and Technology. Enrolling by invitation at 1 site in Jordan. Open to participants aged 7 Years to 13 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-15.

Sponsored by Jordan University of Science and Technology · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Randomized
Ages
7 Years to 13 Years
Sex
All
01

Study summary

This study aims to compare the clinical performance of Prefabricated Zirconia Crowns (PZCs) with that of Custom-made Zirconia Crowns (CZCs) using enhanced clinical protocols.

Read the detailed description

Young permanent molars presenting with gross caries, pulpal treatment or developmental defects often require full coverage restorations. Recently, the Prefabricated Zirconia Crowns (PZCs) have been introduced as a biocompatible and an aesthetically pleasant option with promising outcomes. However, it comes in specific sizes, limited shades and a significant tooth preparation is often required. Custom-made zirconia crowns (CZCs), fabricated using CAD/CAM technology may; offer a favorable aesthetic alternative by ensuring a controlled tooth reduction, precise fit, better aesthetics, and improved retention. Nevertheless, the current evidence concerning its use in young permanent molars remains limited. This study will be a randomised clinical trial that aims to compare the clinical performance of (PZCs) with that of (CZCs) for the restoration of badly carious/destructed young permanent molars in children aged 7-13. Patients will be randomised into two treatment groups using an online block randomisation technique (block size of 6) and sealed-envelope techniques. Clinical parameters: retention, fracture, gingival health and marginal integrity will be evaluated at 3-month, 6-month, and 12-month intervals. In addition, treatment duration, intraoperative patient comfort and immediate postoperative patient satisfaction will be evaluated and compared. The findings of this study are expected to provide evidence on the suitability of CZC for young permanent molars in children. The Null hypothesis is that there is no difference between the two types of crowns in terms of clinical performance and child acceptance.

02

Conditions studied

  • Zirconia Crowns

Keywords

  • Zirconia crowns
  • Prefabricated Zirconia crowns
  • Custom-made Zirconia crowns
  • Children
  • Young permanent molars
03

Who can participate

Ages eligible
7 Years to 13 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Medically fit or with mild systemic illness (ASA I or II).
  • Children who assent to take part in the study with a valid parental consent
  • Children who have at least one first permanent molar requiring a full-coverage restoration (indications for placing a crown include: badly destructed/carious molars, or teeth affected by molar-incisor hypomineralisation (MIH))
  • Maxillary or mandibular fully erupted first permanent molars, regardless of the stage of root development.
  • A cooperative child that accepts dental treatment (Frankle Behaviour Rating Scale #3 or 4).
  • Capable of attending all follow-up sessions.

Exclusion criteria

Exclusion Criteria:

  • Patients outside the required age range
  • Parents/child not willing to participate.
  • Medically compromised patients
  • Partially erupted permanent first molars.
  • Patients with severe malocclusion that prohibits the provision of crowns
  • First permanent molars are not indicated for full coverage restorations.
  • First permanent molars are indicated for extraction.
  • Patients with bruxism or parafunctional habits.
  • Uncooperative children (Frankle Behaviour Rating Scale #1 or 2)
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
50 participants (estimated)

Study arms

  • Experimental
    Prefabricated Zirconia Crowns

    Tooth preparation and cementation of a suitable size of prefabricated Zirconia crown.

    Procedure: Prefabricated Zirconia Crown

  • Experimental
    Custom-made Zirconia Crowns

    Tooth preparation, followed by oral scanning and production and cementation of a zirconia crown using CAD-CAM technology.

    Procedure: Custom-made Zirconia Crowns

Interventions

  • ProcedurePrefabricated Zirconia Crown

    Tooth preparation as per the manufacturer's instructions and cementation of a suitable size of prefabricated Zirconia crown using self-adhesive resin cement.

  • ProcedureCustom-made Zirconia Crowns

    Tooth preparation (1-1.5 mm occlusal, 0.5 to 1.25 mm circumferential, with a shoulder-edge supra-gingival margin), followed by scanning with an intra-oral scanner, then temporisation. A zirconia crown will be produced using CAD-CAM technology and cemented with a self-adhesive resin cement on a different visit.

05

What researchers measure

Primary outcomes

  1. Rate of Crown retention

    Visual-tactile evaluation of the crown retention over time (crown present, loose or lost).

    Time frame: 3,6 and 12 months

  2. Rate of chipping and fracture of the crown

    Clinical evaluation for the presence/absence of crown chipping or fracture

    Time frame: 3,6 and 12 months

  3. Gingival health

    Clinical evaluation of the gingival inflammation ( the gingival index (GI) by Löe \& Silness 1963 )

    Time frame: 3,6 and 12 months

  4. Clinical crown margin extension

    Visual-tactile evaluation for crown margin extension (supra/ equi/sub-- gingival)

    Time frame: 3,6 and 12 months

  5. Radiographic crown margin adaptation

    Evaluation of crown margin adaptation (Geduk et al., 2023)

    Time frame: 6 and 12 months

  6. Clinical crown margin adaptation

    Clinical evaluation of crown margin using an explorer (Geduk et al., 2023)

    Time frame: 3,6 and 12 months

Secondary outcomes

  1. Time taken for intervention

    Total time taken to perform the intervention for each crown (crown preparation, try-in and cementation) in minutes.

    Time frame: Perioperative/Periprocedural: from the beginning of tooth preparation and until the crown is cemented.

  2. Patient satisfaction

    Self-reported child acceptance using a 5-points visual analogue scale

    Time frame: immediately following intervention.

  3. Patient's comfort

    will be evaluated by an observer (research assistant who will be trained, and calibrated) and recorded using the Sound, Eyes, and motor scale (SEM); Based on the intensity of the child's discomfort, each parameter is scored into one of four categories (comfort (score 0), mild discomfort (score 1), moderately painful (score 2), and painful (score 3)). The total score can range from 0 to 9, with 9 indicating the highest level of discomfort.

    Time frame: peri-operatively

06

Study locations

1 site
  • Jordan University of Science and Technology
    Irbid, Jordan
07

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT07704151
Lead sponsor
Jordan University of Science and Technology
Responsible party
Sponsor
First posted
Jul 15, 2026
Start date
Aug 1, 2025
Primary completion
Dec 31, 2027 (estimated)
Completion
Dec 31, 2027 (estimated)
Last update
Jul 15, 2026

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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