An interventional study of VR-Based Intelligent Reading Aid and Natural Vision Reading (No Assistive Device) in Low Vision in Children, sponsored by Beijing Tongren Hospital. Completed at 1 site in China. Open to participants aged 9 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-14.
Sponsored by Beijing Tongren Hospital · Not applicable, Interventional, and Treatment
Low vision substantially impairs reading ability and educational participation in adolescents. Existing assistive technologies, including optical magnifiers and electronic visual aids, are often limited by fragmented system architectures and insufficient support for multimodal cognitive processing.
This study aimed to develop and evaluate a virtual reality (VR)-based intelligent reading aid integrating image enhancement, optical character recognition (OCR), text-to-speech (TTS), and large language model (LLM)-based semantic summarization for low-vision users.
Beijing Tongren Hospital is the lead sponsor of 154 studies on the registry; 49 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Safety Evaluation Cohort Inclusion Criteria：
Exclusion Criteria:
Functional Evaluation Cohort:
Inclusion Criteria:
Exclusion Criteria:
Arm Name：Unaided Reading (Baseline) Arm Type：Active Comparator Intervention Type：Device Intervention Name：Natural Vision Reading (No Assistive Device) Intervention Description： Participants complete standardized Chinese reading tasks relying on natural vision without any visual aid. Each task contains 100 Chinese characters. Reading performance and user satisfaction are evaluated.
Device: VR-Based Intelligent Reading Aid
Arm Name：VR-Based Intelligent Reading Aid Arm Type：Experimental Intervention Type：Device Intervention Name：VR-Based Multimodal Intelligent Reading Aid (Langshiqing Low-Vision Device) Intervention Description： Participants use the VR head-mounted intelligent reading aid to complete the same standardized reading tasks. The device integrates image enhancement, OCR, text-to-speech (TTS) and LLM-based semantic summarization. The test luminance is set at 400 nit (maximum recommended brightness). Each task contains 100 Chinese characters. Duration：Single session, approximately 5 minutes
Device: Natural Vision Reading (No Assistive Device)
Intervention Description： Participants use the VR head-mounted intelligent reading aid to complete the same standardized reading tasks. The device integrates image enhancement, OCR, text-to-speech (TTS) and LLM-based semantic summarization. The test luminance is set at 400 nit (maximum recommended brightness). Each task contains 100 Chinese characters. Duration：Single session, approximately 5 minutes
Participants complete reading tasks with natural vision, without using any assistive device.
Change in Phoria
Variation of ocular phoria before and after single-session VR intelligent reading aid use, to evaluate the impact of near-eye VR optical system on adult eye position stability.
Time frame: within 10 minutes after all reading tasks
Reading Completion Time
Time to finish standardized 100-character Chinese reading tasks (unit: second). Compare results between unaided and VR-assisted conditions.
Time frame: within 10 minutes after all reading tasks
Tear Break-Up Time (TBUT)
Change in tear break-up time before and after VR device use for assessment of ocular surface dryness in adult participants.
Time frame: within 10 minutes after all reading tasks
Accommodative Function
Alteration of eye accommodative function after using the VR reading aid among adult subjects.
Time frame: within 10 minutes after all reading tasks
Simulator Sickness Questionnaire (SSQ)
Scale Description:The SSQ is a self-report questionnaire that assesses VR-related simulator sickness. Each item is rated on a 4-point scale: None (0), Slight (1), Moderate (2), and Severe (3). Through weighted calculations, four scores are derived: Nausea-related subscore (N), Oculomotor-related subscore (O), Disorientation-related subscore (D), and Total Score (TS). Minimum and Maximum Values: * ndividual items: 0 (None) to 3 (Severe) * Total Score (TS): 0 to 235.62 (based on standard weighted scoring) * Nausea subscore (N): 0 to 200.34 * Oculomotor subscore (O): 0 to 200.34 * Disorientation subscore (D): 0 to 292.32 Interpretation:Higher scores indicate worse outcomes (more severe simulator sickness/cybersickness).
Time frame: within 10 minutes after all reading tasks
Best-Corrected Visual Acuity (BCVA)
Change in best-corrected visual acuity before and after VR reading session for adult low-vision users.
Time frame: within 10 minutes after all reading tasks
Intraocular Pressure (IOP)
Fluctuation of intraocular pressure pre and post VR device reading task in adult participants.
Time frame: within 10 minutes after all reading tasks
User Satisfaction Score
100-point satisfaction scale. VR group includes four sub-items: magnification, text-to-speech, OCR and AI summarization (25 points each).
Time frame: within 10 minutes after all reading tasks
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Beijing Tongren Hospital