An observational study in Menopause and Perimenopausal Disorder, sponsored by Bezmialem Vakif University. Not yet recruiting at 1 site in Turkey (Türkiye). Open to female participants aged 40 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-07-09.
Sponsored by Bezmialem Vakif University · Observational
The menopausal transition is associated with substantial hormonal alterations that may adversely affect lower urinary tract function, bowel function, and sexual health. Although these symptoms are common, few studies have comprehensively evaluated all three pelvic floor compartments across different menopausal stages.
The aim of this study is to compare lower urinary tract symptoms, bowel symptoms, and female sexual function among women in the perimenopausal, early postmenopausal, and late postmenopausal stages. In addition, the relationship between menopausal stage and symptom severity will be investigated.
Menopause is characterized by estrogen deficiency, resulting in structural and functional alterations in pelvic floor tissues. Lower urinary tract symptoms, bowel dysfunction, and female sexual dysfunction are increasingly recognized as important health concerns during the menopausal transition.
Despite growing evidence regarding individual pelvic floor disorders, few studies have simultaneously evaluated urinary, colorectal, and sexual symptoms across different menopausal stages.
This study will classify women according to STRAW+10 criteria into:
Perimenopause Early postmenopause Late postmenopause
Participants will undergo a single assessment session. Demographic information together with validated questionnaires will be collected. No intervention or treatment will be provided.
406 studies on the registry are indexed under Lower Urinary Tract Symptoms; 110 are open to participants now.
This study's planned enrollment of 180 is close to the median of 179 across 132 observational studies indexed under Lower Urinary Tract Symptoms.
Browse Lower Urinary Tract Symptoms studies →Bezmialem Vakif University is the lead sponsor of 345 studies on the registry; 58 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Women aged 40-65 years attending the Gynecology and Obstetrics Outpatient Clinic who are classified as perimenopausal, early postmenopausal, or late postmenopausal according to the STRAW+10 criteria. Participants must have an intact uterus and at least one ovary and be able to read and understand Turkish.
Exclusion Criteria:
Perimenopausal women according to STRAW+10 criteria
Other: Assessment for Lower Urinary Tract Symptoms · Other: Assessment for Bowel Symptoms · Other: Constipation Severity Assessment · Other: Sexual Function Assessment
Early postmenopausal women according to STRAW+10 criteria
Other: Assessment for Lower Urinary Tract Symptoms · Other: Assessment for Bowel Symptoms · Other: Constipation Severity Assessment · Other: Sexual Function Assessment
Late postmenopausal women according to STRAW+10 criteria
Other: Assessment for Lower Urinary Tract Symptoms · Other: Assessment for Bowel Symptoms · Other: Constipation Severity Assessment · Other: Sexual Function Assessment
Lower urinary tract symptoms will be assessed using the validated Bristol Female Lower Urinary Tract Symptoms questionnaire. Higher scores indicate greater symptom severity and poorer urinary health-related quality of life.
Bowel symptoms and colorectal-anal distress will be evaluated using the Colorectal Anal Distress Inventory-8. Higher scores indicate greater symptom severity and distress related to bowel dysfunction.
Constipation severity will be assessed using the Cleveland Clinic Constipation Score. Higher scores represent more severe constipation symptoms.
Female sexual function will be assessed using the Female Sexual Function Index, a validated questionnaire evaluating desire, arousal, lubrication, orgasm, satisfaction, and pain. Higher scores indicate better sexual function.
Bristol Female Lower Urinary Tract Symptoms (BFLUTS) Score
Lower urinary tract symptoms will be assessed using the validated Bristol Female Lower Urinary Tract Symptoms questionnaire. Higher scores indicate greater symptom severity and poorer urinary health-related quality of life
Time frame: Baseline (single assessment)
Colorectal Anal Distress Inventory-8 (CRADI-8)
Bowel symptoms and colorectal-anal distress will be evaluated using the Colorectal Anal Distress Inventory-8. Higher scores indicate greater symptom severity and distress related to bowel dysfunction.
Time frame: Baseline (single assessment)
Cleveland Clinic Constipation Score
Constipation severity will be assessed using the Cleveland Clinic Constipation Score. Higher scores represent more severe constipation symptoms.
Time frame: Baseline (single assessment)
Bristol Stool Form Scale
The Bristol Stool Form Scale is a 7-category scale ranging from Type 1 (hard stools) to Type 7 (watery stools). Values range from 1 to 7. Lower scores indicate harder stool consistency, whereas higher scores indicate looser stool consistency.
Time frame: Baseline (single assessment)
Female Sexual Function Index
Female sexual function will be assessed using the Female Sexual Function Index, a validated questionnaire evaluating desire, arousal, lubrication, orgasm, satisfaction, and pain. Higher scores indicate better sexual function.
Time frame: Baseline (single assessment)
Plan to share: Undecided
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This study is not yet recruiting, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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Bezmialem Vakif University