An interventional study of Magnesium Choline Citrate and Placebo in Cognitive Function and Anxiety, sponsored by Nutrisol, LLC. Not yet recruiting at 1 site in Canada. Open to participants aged 9 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-29.
Sponsored by Nutrisol, LLC · Not applicable, Interventional, and Treatment
The goal of this clinical trial is to examine the effect of Magnesium Choline Citrate on cognitive function and anxiety in healthy adolescents and adults. The main questions it aims to answer are:
Researchers will compare Magnesium Choline Citrate with placebo to evaluate its effects on cognitive function and anxiety symptoms. Participants will be asked to:
Individuals of child-bearing potential must confirm negative baseline pregnancy status and agree to use a medically approved method of birth control for the duration of the study. All hormonal birth control must have been in use for a minimum of three months. Acceptable methods of birth control include:
Abstinence and agrees to use contraception if planning on becoming sexually active during the study 3. Has recently noticed a worsening in or wishes to improve one or all of the following:
Exclusion Criteria:
Self-reported ongoing and unstable diseases/conditions in the past six months, including:
Dietary Supplement: Magnesium Choline Citrate
Dietary Supplement: Placebo
Participants will be instructed to take two capsules twice per day with food starting on Day 1.
Participants will be instructed to take two capsules twice per day with food starting on Day 1
PROMIS Cognitive Function- Short Form 8a (baseline to day 84)
Change in cognitive function, as assessed by the PROMIS Cognitive Function- Short Form 8a (≥18 years old) from baseline to Day 84 between Magnesium Choline Citrate and placebo
Time frame: Baseline (day 1) to day 84
Pediatric Cognitive Function - Short Form 7a (baseline to day 84)
Change in cognitive function, as assessed by the Pediatric Cognitive Function - Short Form 7a (9-17 years old) from baseline to Day 84 between Magnesium Choline Citrate and placebo
Time frame: Baseline (day 1) to day 84
PROMIS Cognitive Function- Short Form 8a (baseline to day 42)
Change in cognitive function, as assessed by the PROMIS Cognitive Function- Short Form 8a (≥18 years old) from baseline to Day 42 between Magnesium Choline Citrate and placebo
Time frame: Baseline (day 1) to day 42
Pediatric Cognitive Function - Short Form 7a (baseline to day 42)
Change in cognitive function, as assessed by the Pediatric Cognitive Function - Short Form 7a (9-17 years old) from baseline to Day 42 between Magnesium Choline Citrate and placebo
Time frame: Baseline (day 1) to day 42
PROMIS Emotional Distress - Anxiety - Short Form 8a (baseline to Days 42 and 84)
Change in feelings of anxiety, as assessed by the PROMIS Emotional Distress - Anxiety - Short Form 8a (≥18 years old) from baseline to Days 42 and 84 between Magnesium Choline Citrate and placebo
Time frame: Baseline (day 1) to days 42 and 84
PROMIS Pediatric Anxiety - Short Form 8a (baseline to Days 42 and 84)
Change in feelings of anxiety, as assessed by the PROMIS Pediatric Anxiety - Short Form 8a (9-17 years old) from baseline to Days 42 and 84 between Magnesium Choline Citrate and placebo
Time frame: Baseline (day 1) to days 42 and 84
Incidence of post-emergent adverse events (AE)
Incidence of post-emergent adverse events (AE)
Time frame: Baseline (day 1) to day 84
This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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