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CompletedNCT07673432Updated Jun 29, 2026

A Clinical Trial to Evaluate the Effects of a Plant-Based Liquid Supplement on Metabolic Health and Overall Well-Being

An interventional study of Plant-Based Liquid Supplement in Metabolic Health, Elevated Liver Enzymes and Digestive Symptoms, sponsored by Biocol Labs. Completed at 1 site in United States. Open to participants aged 40 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-06-29.

Sponsored by Biocol Labs · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year after the study started (first participant enrolled Jun 2025, registered Jun 2026).
Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Not applicable
Ages
40 Years to 60 Years
Sex
All
01

Study summary

This single-arm clinical trial will evaluate the effects of a plant-based liquid supplement on metabolic health, digestive health, skin health, and overall well-being. Twenty participants aged 40 to 60 years with elevated alanine transaminase (ALT) or aspartate transaminase (AST) levels will use the supplement daily for 90 days. Participants will complete questionnaires, provide body composition and waist circumference measurements, submit photographs, and undergo blood testing throughout the study. Outcomes include changes in metabolic biomarkers, body composition, digestive symptoms, skin health, and overall well-being.

02

Conditions studied

  • Metabolic Health
  • Elevated Liver Enzymes
  • Digestive Symptoms
03

In context

Lead sponsor

This is the only study on the registry with Biocol Labs as lead sponsor.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
40 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Age 40 to 60 years
  • Elevated ALT or AST identified during prescreening blood testing
  • Currently experiencing at least two of the following:

Stomach discomfort, Constipation, Diarrhea, Heartburn, Bloating, Gas, Abdominal pain, Skin redness or pimples, Sugar cravings

  • Willing to comply with study requirements
  • Willing to discontinue supplements or herbal remedies targeting detoxification, digestive health, liver function, or skin health during the study
  • Willing to avoid starting new products, medications, or supplements targeting detoxification, digestive health, liver function, or skin health
  • Willing to maintain normal diet, sleep patterns, and activity levels
  • Generally healthy without uncontrolled chronic disease
  • Resides in the United States
  • Not participating in another research study during the study period
  • Has access to a study partner to take study photographs

Exclusion criteria

Exclusion Criteria:

  • Severe digestive disorders including acid reflux, IBS, IBD, Crohn's disease, or gastrointestinal tract surgeries
  • Liver disease
  • Known allergy or hypersensitivity to study product ingredients Chronic conditions that would interfere with study participation, including oncological or psychiatric disorders
  • Known severe allergic reactions
  • Pregnant, breastfeeding, or attempting to conceive
  • Unwilling to follow study procedures
  • Stopped hormonal birth control within the past month
  • History of substance abuse
  • Use of prescription diabetes medications, including GLP-1 receptor agonists such as Ozempic, Wegovy, or Mounjaro
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
20 participants (actual)

Study arms

  • Experimental
    Plant-Based Liquid Supplement

    Participants will consume one ampule of the study product diluted in approximately 8 ounces of water before the first meal of the day throughout the study period.

    Dietary Supplement: Plant-Based Liquid Supplement

Interventions

  • Dietary supplementPlant-Based Liquid Supplement

    A liquid dietary supplement containing choline bitartrate, zinc sulfate, manganese sulfate, artichoke leaf extract, fennel extract, rosemary leaf extract, L-arginine monohydrochloride, inositol, bromelain, papain, sorbitol, glycerin, artificial flavour, and potassium sorbate.

06

What researchers measure

Primary outcomes

  1. Change in Body Weight

    Change in body weight measured using a Withings smart scale.

    Time frame: Baseline, Day 30, Day 60, and Day 90.

  2. Change in Waist Circumference

    Change in waist circumference measured using a tape measure and recorded in centimeters.

    Time frame: Baseline, Day 7, Day 30, Day 60, and Day 90.

  3. Change in Body Fat Mass

    Change in body fat mass measured using a Withings smart scale.

    Time frame: Baseline, Day 7, Day 30, Day 60, and Day 90.

  4. Change in Lean Body Mass

    Change in lean body mass measured using a Withings smart scale.

    Time frame: Baseline, Day 7, Day 30, Day 60, and Day 90.

  5. Change in Visceral Fat Index

    Change in visceral fat index measured using a Withings smart scale.

    Time frame: Baseline, Day 7, Day 30, Day 60, and Day 90.

  6. Change in Alanine Aminotransferase (ALT)

    Change in serum alanine aminotransferase concentration measured by hepatic function panel.

    Time frame: Baseline, Day 30, Day 60, and Day 90.

  7. Change in Aspartate Aminotransferase (AST)

    Change in serum aspartate aminotransferase concentration measured by hepatic function panel.

    Time frame: Baseline, Day 30, Day 60, and Day 90

  8. Change in Alkaline Phosphatase (ALP)

    Change in serum alkaline phosphatase concentration measured by hepatic function panel.

    Time frame: Baseline, Day 30, Day 60, and Day 90.

  9. Change in Total Bilirubin

    Change in serum total bilirubin concentration measured by hepatic function panel.

    Time frame: Baseline, Day 30, Day 60, and Day 90.

  10. Change in Total Cholesterol

    Change in serum total cholesterol concentration measured by lipid panel.

    Time frame: Baseline, Day 30, Day 60, and Day 90.

Secondary outcomes

  1. Change in Participant-Reported Bloating Severity

    Change in participant-reported bloating severity assessed by study questionnaire.

    Time frame: Baseline, Day 1, Day 3, Day 7, Day 30, Day 60, and Day 90.

  2. Change in Participant-Reported Flatulence Severity

    Change in participant-reported flatulence severity assessed by study questionnaire.

    Time frame: Baseline, Day 1, Day 3, Day 7, Day 30, Day 60, and Day 90.

  3. Change in Participant-Reported Heartburn Severity

    Change in participant-reported heartburn severity assessed by study questionnaire.

    Time frame: Baseline, Day 1, Day 3, Day 7, Day 30, Day 60, and Day 90.

  4. Change in Participant-Reported Digestive Comfort

    Change in participant-reported digestive comfort assessed by study questionnaire.

    Time frame: Baseline, Day 1, Day 3, Day 7, Day 30, Day 60, and Day 90.

  5. Change in Participant-Reported Skin Health

    Change in participant-reported skin health assessed by study questionnaire.

    Time frame: Baseline, Day 1, Day 3, Day 7, Day 30, Day 60, and Day 90.

07

Study locations

1 site
  • Citruslabs
    Las Vegas, Nevada 89118, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 29, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07673432
Lead sponsor
Biocol Labs
Collaborators
Citruslabs
Responsible party
Sponsor
First posted
Jun 29, 2026
Start date
Jun 5, 2025
Primary completion
Jan 15, 2026
Completion
Jan 15, 2026
Last update
Jun 29, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.

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