An interventional study of Carpal tunnel surgery and Questionnaires in Carpal Tunnel Syndrome (CTS), sponsored by GCS Ramsay Santé pour l'Enseignement et la Recherche. Terminated at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-07-16.
Sponsored by GCS Ramsay Santé pour l'Enseignement et la Recherche · Not applicable, Interventional, and Other
Carpal tunnel syndrome is a common condition caused by compression of the median nerve. Tingling in the first three or four fingers, usually at night or upon waking, is the most frequent symptom. Reduced sensation in the fingers and clumsiness can also occur, and in severe cases, there may even be weakness in thumb abduction with thenar muscle wasting. Carpal tunnel syndrome (CTS) is the most commonly diagnosed nerve compression syndrome. The annual incidence of diagnosis varies depending on the study and the country. It's estimated at 3.8 per thousand in the general population, 1 to 2 per thousand in men, 4 to 5 per thousand in women, with a peak between ages 40 and 60.
Medical treatment combines removing a microtraumatic factor, immobilization with a brace, and giving 1 to 2 cortisone injections into the carpal tunnel. The results are good in purely sensory cases. If it doesn't work, things get worse despite treatment, or in severe cases from the start (severe sensory problems, loss of strength, muscle wasting), surgery is recommended.
Several teams have recently demonstrated the benefits of using a minimally invasive ultrasound-guided surgical technique to perform flexor retinaculum sectioning under ultrasound guidance. This technique offers increased safety thanks to continuous ultrasound monitoring and the visualization of median nerve variants. Rojo et al. compared ultrasound surgery with a 1 mm incision to mini-open surgery with a 20 mm incision in 128 patients. This study suggests that a minimally invasive approach could allow for faster functional pain recovery compared to conventional surgery.
This project is based on the hypothesis that the proposed ultrasound-guided percutaneous release technique has an efficacy and tolerability profile suitable for widespread use in the indication of carpal tunnel syndrome resistant to conservative treatment, and that it can therefore reduce the need for conventional surgery in this indication.
589 studies on the registry are indexed under Carpal Tunnel Syndrome; 140 are open to participants now.
This study's enrollment of 7 is below the median of 60 across 445 interventional studies indexed under Carpal Tunnel Syndrome.
Browse Carpal Tunnel Syndrome studies →GCS Ramsay Santé pour l'Enseignement et la Recherche is the lead sponsor of 198 studies on the registry; 94 are open to participants now.
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Procedure: Carpal tunnel surgery · Other: Questionnaires
Procedure: Carpal tunnel surgery · Other: Questionnaires
The aim of this study is to compare the conventional surgery to the percutaneous ultrasound-guided carpal tunnel release procedure. One group is doing the conventional surgery and the other the procédure to evaluate.
EVA, Boston and Quick Dash questionnaires : all study visits
Severity of symptoms" subscore of the Boston Questionnaire
The "Severity of symptoms" subscore of the Boston Questionnaire, specific to carpal tunnel syndrome, 3 months post-intervention, assessed by the clinical research associate, blinded to the procedure performed. Eleven questions with a score between 1 and 5 for each items. The final score is between 11 (no symptoms) and 55 (very high severity).
Time frame: 3 months after surgery
This study is terminated, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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GCS Ramsay Santé pour l'Enseignement et la Recherche