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Not yet recruitingNCT07661147REUpdated Jun 22, 2026

Aerobic Versus Resistance Exercises on Disability After Abdominal Myomectomy

An interventional study of aeropic exercises and resistance exercises in Myomectomy, sponsored by Cairo University. Not yet recruiting. Open to female participants aged 30 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-06-22.

Sponsored by Cairo University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
30 Years to 60 Years
Sex
Female
01

Study summary

This study will be conducted to compare aerobic and resistance exercises on disability after abdominal myomectomy.

Read the detailed description

Abdominal myomectomy is a classic surgery for uterine fibroids removal without removing the uterus, in line to reserve patients' fertility. Uterine fibroids are the most common uterus non-cancerous tumors with a prevalence of 70% to 80% in women. Although only 25% to 30% of women are affected by symptoms like pelvic pain, pressure, heavy menses, recurrent pregnancy loss, and infertility, it remains the leading indication for hysterectomy and a common women's health concern. No doubt that abdominal myomectomy almost recommended preserving fertility, plus alleviating uterine fibroids clinical manifestations without resorting to a hysterectomy.Recent studies have explored the combined effects of aerobic and resistance exercises as part of a comprehensive rehabilitation program. Research suggests that combining aerobic and resisted exercise training might gain superior functional benefits compared to using one exercise training program. A recent clinical trial conducted by demonstrated that combination of aerobic and resistance exercises almost represented with reduced fatigue symptoms, which resulted in better improved overall functional capacity, and earlier recovery in compared to those who engaged in only one exercise training protocol. The rationale behind this combination approach is that aerobic exercise improves cardiovascular fitness and endurance, while resistance training focuses on building muscle strength and improving muscular endurance, providing a more holistic approach to recover.

Finally, postoperative rehabilitation following myomectomy must also consider the prevention of complications such as abdominal scarring, hernias, and pelvic floor dysfunction, which can arise as a result of the surgery. Aerobic and resistance exercises have been shown to play a crucial role in minimizing these risks by promoting muscle strength, enhancing tissue healing, and improving flexibility. Research suggests that exercise can stimulate tissue remodeling and improve the elasticity of the abdominal wall, which reduces the likelihood of the formation of problematic scars or hernias. Furthermore, aerobic and resistance exercises support the pelvic floor muscles, helping to prevent dysfunction and incontinence, which are common concerns following abdominal surgeries like myomectomy. By addressing both muscular strength and flexibility, a balanced approach to rehabilitation can enhance recovery and reduce the risk of long-term complications.

02

Conditions studied

  • Myomectomy

Keywords

  • aerobic exercises
  • resistance exercises
  • disability
  • abdominal myomectomy
03

In context

Lead sponsor

Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.

Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
30 Years to 60 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Inclusion criteria

  • All patients are conscious and ambulant.
  • Their ages ranged from 30-60 years old.
  • All patients will be under post abdominal myomectomy (6-12 months) management program.
  • All patients will not suffer from any complication post abdominal myomectomy, except weakness of abdominal muscles.
  • All patients will receive and agreed to sign the informed consent form.

Exclusion criteria

Exclusion Criteria:

  • The patient who has cardiovascular diseases, or uncontrolled hypertension.
  • The patient who has cardiac pacemakers or other implanted electronic devices.
  • Uncooperative patients.
  • Patients who have cardiopulmonary diseases.
  • Patients who have psychic disorders.
  • Patients with neuromuscular diseases.
  • Pregnant female.
  • Patients who have any endocrine, metabolic, renal or hepatic diseases. Patients who have an open wound at or near the treatment site.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
60 participants (estimated)

Study arms

  • Experimental
    aeropic exercises

    Thirty patients who have undergone abdominal myomectomy will receive resisted exercises program for, 3 sessions per week for 12 weeks in addition to the routine medical treatment

    Other: aeropic exercises

  • Experimental
    Resistance Exercises

    thirty patients who have undergone abdominal myomectomy will receive aerobic exercises program for, 3 sessions per week for 12 weeks in addition to the routine medical treatment

    Other: resistance exercises

Interventions

  • Otheraeropic exercises

    * Treadmill Walking: will begin at a low speed and incline, progressing gradually based on endurance. * Stationary Cycling: Low resistance cycling, will focus on steady, rhythmic pedaling. * Step Aerobics: Low-impact stepping movements to music, with a focus on maintaining proper posture. * The workload was increased incrementally by adjusting: Speed (walking/cycling pace), Resistance (stationary cycling or water exercises), Duration (gradually increasing from 20 to 30 minutes for the main session), Intensity progression was based on the Rate of Perceived Exertion (RPE) or patient-reported effort, ensuring safe advancement.

  • Otherresistance exercises

    The patient will be prepared with preparatory explanations about each tool will be utilized i.e., sand bags, thera Bands, and swiss ball.Twelve exercises will be utilized for 12 weeks, three sessions/ week. The intervention will be applied by a trained physical therapist. First of all, each participant will be instructed to relax thighs, bottom and abdomen musculature.Each participant will be able to do 10 slow contractions each time, holding them for 10 seconds each with rests of 4 seconds in between. Then do not hold your breath or tighten rectus abdominis muscles at the same time. Will instruct participants to try holding each squeeze for a few seconds utilizing sand bags, thera band, and swiss balls.

06

What researchers measure

Primary outcomes

  1. functional disability

    Functional Independence Measure Scale was used to assess functional disability. it includes 18 items divided into two domains: Motor tasks (13 items) and cognitive tasks (5 items). score (1-7) to each of the 18 items based on the patient's observed performance.-Total FIM score range: 18 (complete dependence) to 126 (complete independence).

    Time frame: up to 12 weeks

  2. pain intensity

    Visual analogue scale consisted of a line, usually 100mm long, the patient was instructed to place a vertical mark on to indicate his pain, ranging from no pain or discomfort (0), to the worst pain (100) that the patient could feel

    Time frame: up to 12 weeks

Secondary outcomes

  1. rectus abdominal muscle strength

    The manual muscle test is a valid and reliable dependent in assessment of musculoskeletal musculatures obtained using the procedure. Each dimension is rated on a 7-point scale: 7 is complete independence, 6 is modified independence, 5 equals supervision or setup, 4 equals minimal contact assistance (client expends 75% or more of the effort), 3 is moderate assistance (client expends between 50% and 75% of the effort), 2 is maximal assistance (client expends between 25% and 50% of the effort), and 1 equals total assistance (client expends \<25% of the effort).

    Time frame: up to 12 weeks

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 22, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07661147
Lead sponsor
Cairo University
Responsible party
Norhan Khalaf Awad Ahmed (principle investigator : norhan khalaf awad ahmed, Cairo University) — Principal investigator
First posted
Jun 22, 2026
Start date
Jun 25, 2026 (estimated)
Primary completion
Oct 30, 2026 (estimated)
Completion
Oct 30, 2026 (estimated)
Last update
Jun 22, 2026

Study contacts

norhan khalaf, master
Contact
Khalafnourhan.nk@gmail.com
01018426731
norhan khalaf
Contact
Khalafnourhan.nk@gmail.com
01018426731

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.

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