An interventional study of After and Before in Partially Edentulous Mandible, sponsored by Cairo University. Not yet recruiting at 1 site in Egypt. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-06-18.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
The aim of the study is to evaluate the occlusal contact distribution in digitally fabricated implant-retained fixed partial dentures in mandibular Kennedy Class II patients before and after artificial intelligence bite optimization.
The recruited patients will be screened for proper bone architecture and CBCTs will be taken for proper virtual implant planning. Two implants will be placed in the edentulous span in all participants. All surgical steps will be held according to standard protocol. After the implant osseointegration period, the prosthetic phase will start with implant exposure and placement of multiunit abutments. After gingival healing, intraoral scans for the implants timing using abutment level scan bodies will be taken. Then, the fabrication of implant-retained fixed partial denture will be done with a fully digital workflow. The data acquisition will take place by scanning the patients using Medit intraoral scanner. Then, the scanned stls will be imported in 3shape software version 2024 and bite optimization module in it will be run. It automatically recalculates the position of the bite relation using its integrated AI. After that, the resulted STLs will be exported and re-imported to ExoCAD software to design the prostheses.
Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.
Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
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Exclusion Criteria:
The recruited patients will be screened for proper bone architecture and CBCTs will be taken for proper virtual implant planning. Two implants will be placed in the edentulous span in all participants. All surgical steps will be held according to standard protocol. After the implant osseointegration period, the prosthetic phase will start with implant exposure and placement of multiunit abutments. After gingival healing, intraoral scans for the implants timing using abutment level scan bodies will be taken. Then, the fabrication of implant-retained fixed partial denture will be done with a fully digital workflow.
Procedure: Before
The data acquisition will take place by scanning the patients using Medit intraoral scanner. Then, the scanned stls will be imported in 3shape software version 2024 and bite optimization module in it will be run. It automatically recalculates the position of the bite relation using its integrated AI. After that, the resulted STLs will be exported and re-imported to ExoCAD software to design the prostheses.
Procedure: After
The data acquisition will take place by scanning the patients using Medit intraoral scanner. Then, the scanned stls will be imported in 3shape software version 2024 and bite optimization module in it will be run. It automatically recalculates the position of the bite relation using its integrated AI. After that, the resulted STLs will be exported and re-imported to ExoCAD software to design the prostheses.
The recruited patients will be screened for proper bone architecture and CBCTs will be taken for proper virtual implant planning. Two implants will be placed in the edentulous span in all participants. All surgical steps will be held according to standard protocol. After the implant osseointegration period, the prosthetic phase will start with implant exposure and placement of multiunit abutments. After gingival healing, intraoral scans for the implants timing using abutment level scan bodies will be taken. Then, the fabrication of implant-retained fixed partial denture will be done with a fully digital workflow.
Occlusal contact distribution
The 1ry outcome will be assessed on the day of the prosthesis delivery. First, the reading of the occlusal contact distribution will be taken by using the T-scan device before seating the prosthesis intraorally. Then, the retained fixed prosthesis will be seated on the implant abutment, and the prosthetic screw will be screwed to the optimum torque. Another reading of the occlusal contact distribution will be taken by using the T-scan device after seating and torquing the prosthesis intraorally. Finally, the screw access channels will be closed by flowable resin composite material.
Time frame: From enrollment till the end of the study 17 weeks
Plan to share: No
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This study is not yet recruiting, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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Cairo University