An interventional study of Preferred Music and Matched Non-preferred Music in Procedural Sedation and Dreams, sponsored by Wonkwang University Hospital. Completed at 1 site in South Korea. Open to participants aged 19 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-14.
Sponsored by Wonkwang University Hospital · Not applicable, Interventional, and Supportive care
This randomized clinical trial will evaluate whether music delivered through closed-back headphones during intravenous propofol sedation affects dreaming and the overall sedation experience. Adults scheduled for elective procedures under spinal anesthesia or peripheral nerve block with propofol sedation will be randomly assigned to one of three groups: patient-selected preferred music, matched non-preferred music, or silence with identical headphones.
The main purpose of the study is to determine whether listening to music increases the occurrence of dream recall compared with silence, and whether personally preferred music makes recalled dreams more pleasant than matched non-preferred music. Dream recall and dream pleasantness will be assessed after recovery using a standardized interview. The study will also evaluate dream content, patient satisfaction, sedative and opioid requirements, hemodynamic variability, postoperative pain, nausea and vomiting, recovery time, and adverse events.
This study is intended to determine whether a simple, low-cost headphone-based music intervention can improve patient-centered quality of propofol sedation without compromising safety.
Dreaming during intravenous propofol sedation is common and may influence how patients remember their perioperative experience. External auditory stimulation can sometimes be processed during sedation and may be incorporated into dream content. Music is a practical auditory intervention because it can be delivered through headphones without interfering with anesthetic care or the surgical workflow. However, it remains unclear whether music itself increases dream recall during propofol sedation, and whether patient-selected music provides additional benefit beyond exposure to music with similar acoustic features.
The modified Brice interview will be administered as soon as the participant has adequately recovered consciousness and is able to communicate in the PACU. Because dream recall may fade over time, the interview will be conducted at the earliest feasible time point after recovery of consciousness and no later than 60 minutes after PACU arrival.
This single-center, parallel-group, three-arm randomized controlled trial will compare three auditory conditions during propofol sedation: preferred music, matched non-preferred music, and silence. Participants assigned to the preferred music group will listen to one personally selected track through closed-back headphones. Participants assigned to the matched non-preferred music group will listen to a pleasant but non-selected track matched to the preferred music by genre family, tempo, and loudness. Participants assigned to the silence control group will wear identical closed-back headphones without music playback. In all groups, the assigned auditory condition will begin shortly before sedative administration and continue until the end of the sedation period.
The study population will consist of adults undergoing elective procedures under spinal anesthesia or peripheral nerve block with intravenous propofol sedation. Propofol sedation will be administered according to a standardized protocol and titrated to a predefined sedation depth using clinical sedation scales, with processed electroencephalographic monitoring recorded when available. Standard intraoperative monitoring will be performed according to institutional anesthetic practice.
The study has two main comparisons. First, the two music groups will be pooled and compared with the silence group to assess whether auditory stimulation increases dream recall. Second, the preferred music group will be compared with the matched non-preferred music group to assess whether personalization improves dream pleasantness among participants who recall dreams. Dream recall and dream pleasantness will be assessed in the post-anesthesia care unit using a standardized, neutral interview after participants meet predefined recovery-readiness criteria.
Additional assessments will include coded dream content, auditory salience, emotional valence, vividness, perceived control within the dream, patient satisfaction, propofol dose, opioid use, hemodynamic variability, recovery time, postoperative pain, postoperative nausea and vomiting, and adverse events. Dream narratives will be coded by blinded assessors using a prespecified codebook. Outcome assessors, content coders, and statisticians will remain blinded to group allocation whenever feasible.
The overall aim is to determine whether structured headphone-based music, particularly patient-preferred music, can improve the subjective quality of propofol sedation while maintaining clinical safety. The findings may inform whether routine music delivery and optional music preference capture should be incorporated into perioperative sedation workflows.
Wonkwang University Hospital is the lead sponsor of 26 studies on the registry; 1 is open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
ASA physical status
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants assigned to this arm will listen to one personally selected preferred music track through identical closed-back headphones during intravenous propofol sedation. Playback will begin 1-2 minutes before sedative administration and continue until the end of the sedation period. The track may include either lyrical or instrumental music according to participant preference.
Behavioral: Preferred Music
Participants assigned to this arm will listen to one pleasant but non-selected music track through identical closed-back headphones during intravenous propofol sedation. The track will be matched to the participant's preferred music by genre family, tempo, and loudness, but it will not be personally selected by the participant. Playback will begin 1-2 minutes before sedative administration and continue until the end of the sedation period.
Behavioral: Matched Non-preferred Music
Participants assigned to this arm will wear identical closed-back headphones during intravenous propofol sedation, but no audio will be played. The headphones will be applied for the same period as in the music arms, beginning 1-2 minutes before sedative administration and continuing until the end of the sedation period. This arm controls for headphone use, attention, and expectancy without auditory stimulation.
Behavioral: Silence Control
A personally selected music track will be played through closed-back headphones during intravenous propofol sedation.
Also known as: Patient-selected music Personalized music
A pleasant, non-selected music track matched by genre, tempo, and loudness will be played through closed-back headphones during intravenous propofol sedation.
Also known as: Matched music Non-selected music
Participants will wear identical closed-back headphones during intravenous propofol sedation, but no audio will be played.
Also known as: Headphones without playback No-audio control
Dream Incidence
Occurrence of dream recall after intravenous propofol sedation, assessed using a neutral modified Brice interview. Participants will be classified as having dream recall or no dream recall.
Time frame: At first adequate recovery of consciousness in the post-anesthesia care unit, up to 60 minutes after PACU arrival
Dream Pleasantness
Pleasantness of recalled dreams among participants who report dream recall, assessed using a 0 to 10 numeric rating scale, where higher scores indicate more pleasant dreams.
Time frame: At first adequate recovery of consciousness in the post-anesthesia care unit, up to 60 minutes after PACU arrival
Within 60 minutes after arrival in the post-anesthesia care unit
Degree of auditory salience in recalled dream content, assessed by blinded content coders using a 0 to 3 scale, where higher scores indicate greater auditory salience.
Time frame: At first adequate recovery of consciousness in the post-anesthesia care unit, up to 60 minutes after PACU arrival
Affect Valence of Dream Content
Emotional valence of recalled dream content, assessed by blinded content coders using a scale from -2 to +2, where higher scores indicate more positive affect.
Time frame: At first adequate recovery of consciousness in the post-anesthesia care unit, up to 60 minutes after PACU arrival
Dream Vividness
Vividness of recalled dreams, assessed using a 0 to 10 numeric rating scale, where higher scores indicate more vivid dream experiences.
Time frame: At first adequate recovery of consciousness in the post-anesthesia care unit, up to 60 minutes after PACU arrival
Sense of Control in Dream
Participant-reported sense of control or agency within the recalled dream, assessed using a 0 to 10 numeric rating scale, where higher scores indicate greater perceived control.
Time frame: At first adequate recovery of consciousness in the post-anesthesia care unit, up to 60 minutes after PACU arrival
Patient Satisfaction With Sedation Experience
Participant satisfaction with the sedation experience will be assessed using a 5-point Patient Satisfaction Scale, ranging from 1 to 5. A score of 1 indicates very dissatisfied, and a score of 5 indicates very satisfied. Higher scores indicate greater satisfaction with the sedation experience.
Time frame: Assessed once at discharge from the post-anesthesia care unit, approximately within 2 hours after completion of sedation
This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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Wonkwang University Hospital