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CompletedNCT07633860Updated Jun 10, 2026

Sellar Masses: Clinical and Imaging Features With Correlation to Histopathology and Surgical Approach

An observational study in Sellar Mass and Pituitray Tumor, sponsored by Arab Board of Neurosurgery. Completed at 1 site in Yemen. Open to participants aged 11 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-06-10.

Sponsored by Arab Board of Neurosurgery · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
49
Ages
11 Years to 65 Years
Sex
All
01

Study summary

The goal of this observational study is to learn about the clinical spectrum of sellar masses, aiming to understand the correlation between the imaging features and the future surgical approach and histopathology results.

The main question it aims to answer is:

Does being both LMIC and conflict country change the global data!? Participants were included during a period of 3 years in a governmental hospital TMGH.

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Conditions studied

  • Sellar Mass
  • Pituitray Tumor

Keywords

  • Histopathology
  • Sellar Mass
  • Clinical spectrum
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In context

Lead sponsor

This is the only study on the registry with Arab Board of Neurosurgery as lead sponsor.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
11 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

included all Patients presenting with sellar region masses from December 2022 to December 2025, at Neurosurgical department at TMGH

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Radiologically confirmed sellar, suprasellar, or parasellar mass.
  • Surgical candidacy
  • Histopathological confirmation
  • Age ≥ 11 year

Exclusion criteria

Exclusion Criteria:

  • Incomplete diagnostics
  • Recurrent disease
  • Primary disease.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Metastases

Cancer that has spread from where it began to other parts of the body. “Metastatic” cancer is cancer that has spread this way.

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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
49 participants (actual)
Target follow-up
21 Days
Patient registry
Yes

Groups and cohorts

  • Patients with confirmed sellar masses

    Patients withe age of 11 to 65, who was diagnosed with sellar mass using MRI, and get treated surgically

    Procedure: Craniectomy

Interventions

  • ProcedureCraniectomy

    Bicoronal vs. Pterional approach vs endoscopic

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What researchers measure

Primary outcomes

  1. Correlation between pre-operative radiological features and definitive histopathological diagnosis.

    To evaluate the diagnostic accuracy of pre-operative magnetic resonance imaging (MRI) by determining the percentage of cases where pre-operative radiological features match the definitive post-operative histopathological classification (e.g., pituitary adenoma, craniopharyngioma, meningioma).

    Time frame: 3 years

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Study locations

1 site
  • Thawrh General Modern Hospital
    Sanaa, 975, Yemen
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References and documents

Individual participant data

Plan to share: Undecided — Individual participant data will not be shared publicly to protect patient confidentiality and privacy. The informed consent obtained from the participants covers the publication of aggregated study findings within the manuscript and tables only, and does not include explicit permission for the public disclosure of raw, de-identified individual clinical or radiological datasets."

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 10, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07633860
Lead sponsor
Arab Board of Neurosurgery
Responsible party
Waad Sadek Al.Hakimi (Neurosurgical resident, Arab Board of Neurosurgery) — Principal investigator
First posted
Jun 8, 2026
Start date
Dec 1, 2022
Primary completion
Dec 1, 2025
Completion
Dec 1, 2025
Last update
Jun 10, 2026

Study contacts

Adnan Al- Awdi, Neurosurgical consultant
study director · Arabic Board of Neurosurgery MD

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.

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