ClinicalTrials.gg
Not yet recruitingNCT07633834Updated Jun 8, 2026

Evaluation of Corrective Surgery Versus Dental Implants in Compromised Mandibular Molars

An interventional study of hemi sectioning in Root Caries and Vertical Root Fracture, sponsored by Ain Shams University. Not yet recruiting. Open to participants aged 21 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-06-08.

Sponsored by Ain Shams University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
28
Allocation
Randomized
Ages
21 Years to 60 Years
Sex
All
01

Study summary

This study seeks to assess the clinical, radiographic, and patient-reported outcomes of hemisection versus implant over a 12 months period, generating robust evidence to guide clinical decision-making and enhance patient care.

02

Conditions studied

  • Root Caries
  • Vertical Root Fracture

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03

In context

Root Caries

39 studies on the registry are indexed under Root Caries; 14 are open to participants now.

This study's planned enrollment of 28 is below the median of 62 across 35 interventional studies indexed under Root Caries.

Browse Root Caries studies →

Lead sponsor

Ain Shams University is the lead sponsor of 1,950 studies on the registry; 429 are open to participants now.

Of its 35 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
21 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Good oral hygiene and motivation for follow-up care.
  • Ability to understand and sign .
  • Localized Root/Periodontal Disease: Severe attachment loss or bone loss (e.g., severe localized periodontitis) affecting the mesial root, while the other root remains healthy.
  • Furcation Involvement: Class II or III furcation involvements where the disease cannot be treated by conventional methods.
  • Vertical root fracture confined to the mesial root.
  • Non-treatable perforation in the mesial root.
  • Extensive sub-gingival root caries affecting the mesial root.
  • Extensive un-treatable internal and external root resorption related to the mesial root.

Exclusion criteria

Exclusion Criteria:

  • Uncontrolled systemic diseases (e.g., diabetes mellitus, bleeding disorders, ).
  • Fused or poorly shaped roots,
  • Active periodontal or endodontic infection at adjacent teeth that may interfere with treatment outcomes.
  • Severe bruxism or occlusal parafunction.
  • History of radiation therapy in the head and neck region.
  • Pregnancy or lactation.
  • Poor compliance or inability to attend follow-up visits.
  • Smoking more than 10 cigarettes per day.
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

Immunosuppression

A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.

Read whether the line is about a condition or about medicines, and which medicines and doses it means.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
28 participants (estimated)

Study arms

  • Experimental
    Hemisection

    patients in this group will have hemi sectioning to their compromised mandibular molars

    Procedure: hemi sectioning

  • No intervention
    dental implants

    patients will undergo extraction and replaced with dental implants

Interventions

  • Procedurehemi sectioning

    one root will be extracted and the other root will be preserved

06

What researchers measure

Primary outcomes

  1. • Regulation of clinical signs and symptoms

    Patient-reported outcomes, including satisfaction, masticatory efficiency, and oral comfort measured by a visual analog scale (VAS).

    Time frame: 12 months

Secondary outcomes

  1. Assessment of radiographic bone changes

    * Radiographic bone level changes around the retained root or implant. * Detection of any radiographic signs of pathology or treatment failure. Measurements will be recorded in millimeters (mm) using digital radiographic software calibration tools.

    Time frame: 12 months

07

Study locations

No study locations are listed for this record.

08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Jan 2027; primary completion for Jan 2027, 0 months later.

Of 21 interventional studies with no phase under Root Caries, half reached primary completion within 30 months of starting (the median), counting those still running; a quarter within 23 and three quarters within 55. This study's planned 0 months is below that.

How these figures are worked out, and which studies are left out of them.

Registered
May 24, 2026
First posted
Jun 8, 2026
StartEst.
Jan 1, 2027
Primary completionEst.
Jan 1, 2027
CompletionEst.
Jan 1, 2028
Last update
Jun 8, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jun 8, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07633834
Responsible party
yomna tarek (Assistant Lecturer at department of Endodontics, Ain Shams University) — Principal investigator
First posted
Jun 8, 2026
Start date
Jan 1, 2027 (estimated)
Primary completion
Jan 1, 2027 (estimated)
Completion
Jan 1, 2028 (estimated)
Last update
Jun 8, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in May 2026. You cannot join it, but the record below documents what was studied.

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