An interventional study of Intensive training in Healthy Volunteers, sponsored by Centre Hospitalier Universitaire de Saint Etienne. Recruiting at 1 site in France. Open to participants aged 25 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-06-04.
Sponsored by Centre Hospitalier Universitaire de Saint Etienne · Not applicable, Interventional, and Other
We hypothesize, based on field and scientific data, that setting a very ambitious goal such as completing a mountain ultra-marathon could motivate sedentary and inactive individuals not only to begin training but also to follow a progressive yet extremely ambitious program that has not yet been studied comprehensively. Indeed, the effects of intense and prolonged endurance training (18 months) on the health and performance of completely sedentary individuals have never been investigated exhaustively.
332 studies on the registry are indexed under Sedentary Behavior; 156 are open to participants now.
This study's planned enrollment of 40 is below the median of 70 across 287 interventional studies indexed under Sedentary Behavior.
Browse Sedentary Behavior studies →Centre Hospitalier Universitaire de Saint Etienne is the lead sponsor of 578 studies on the registry; 128 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
From March 1, 2026 to August 2027, participants will follow individualized coaching: starting at 5-6 hours per week and progressing to 7-10 hours (rarely 15 hours) per week before mountain ultra marathon
Behavioral: Intensive training
participants will follow individualized coaching: starting at 5-6 hours per week and progressing to 7-10 hours (rarely 15 hours) per week before mountain ultra marathon
Transition from sedentary lifestyle to regular activity and completion of a 100 km ultra-trail
Percentage of participants who (i) become sufficiently active to be ready to start the Courmayeur-Champex-Chamonix (CCC) 100 km ultra-trail of the Ultra Trail du Mont-Blanc, and (ii) complete the 100 km CCC race.
Time frame: up to 18 months
Safety and tolerance of progressive endurance training
Rate of injuries or adverse events reported weekly, and dropout rate over the 18-month training period.
Time frame: Weekly reporting during the 18-month intervention period
Feasibility and adherence to the endurance training program
Proportion of scheduled training sessions completed by participants and the percentage of participants finishing the 100 km CCC ultra-trail among those who started the race.
Time frame: up to 18 months
Plan to share: Undecided — we are not decided for the moment
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Centre Hospitalier Universitaire de Saint Etienne