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Not yet recruitingNCT07620444Updated Jun 2, 2026

Spectral Precise Image-Colon Cancer

An observational study in Colon Cancer Patients, sponsored by Philips Clinical & Medical Affairs Global. Not yet recruiting at 1 site in China. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-02.

Sponsored by Philips Clinical & Medical Affairs Global · Observational

Study type
Observational
Model
Case-control
Time perspective
Cross-sectional
Enrollment
100
Ages
18 Years and older
Sex
All
01

Study summary

This is a single-center, comparative, observational study. Datasets will be collected from patients with pathologically confirmed colon cancer who undergo abdomen-pelvis enhanced spectral CT scan.

Read the detailed description

This is a single-center, comparative, observational study. Datasets will be collected from patients with pathologically confirmed colon cancer who undergo abdomen-pelvis enhanced spectral CT scan at investigational center, including retrospective and prospective data. Based on the Dose Right Index (DRI) derived from CT image data, relevant data will be collected at a 1:1 ratio for the conventional radiation dose group (RD group, DRI = 21) and the low radiation dose group (LD group, DRI = 18). A total of 100 cases of datasets is expected to be collected. All CT raw data will be transmitted to Philips after the completion of the de-identification process. For the three-phase data of the LD group (plain scan, arterial phase and venous phase), offline reconstruction will be performed using the Spectral Precise Image algorithm to generate conventional images and VMI-40 keV images. A total of six image sequences will be quantitatively and qualitatively evaluated and compared. For both groups, conventional images and VMI-40 keV images will be reconstructed using iDose4.

02

Conditions studied

  • Colon Cancer Patients

Keywords

  • Spectral Precise Image
03

In context

Lead sponsor

Philips Clinical & Medical Affairs Global is the lead sponsor of 82 studies on the registry; 24 are open to participants now.

Of its 13 completed or terminated interventional studies of FDA-regulated products, 10 (77%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients with colon cancer aged 18.

Inclusion criteria

  1. Patients pathologically confirmed with colon cancer via endoscopic biopsy.
  2. Patients who underwent preoperative abdominopelvic enhanced spectral CT.
  3. Study participant with age ≥ 18 years old.
  4. Study participants that have signed Informed Consent Form (ICF).

Exclusion criteria

Exclusion Criteria:

  1. The clinical data or pathological information is considered incomplete after evaluation by the investigator.
  2. The investigator determined that poor image quality (e.g. obvious artifacts, missing critical scan layers) would not satisfy post-processing analysis.
  3. Data of patients deemed inappropriate for inclusion after evaluation by the investigator.
05

Study design

Observational model
Case-control
Time perspective
Cross-sectional
Enrollment
100 participants (estimated)
Target follow-up
1 Day
Patient registry
Yes

Interventions

  • DeviceThis is an observational study

    This is an observational study

06

What researchers measure

Primary outcomes

  1. subjective overall Image quality using 5-point Likert scale(1-5)

    Radiologist will evaluate the overall image quality using 5 Likert scale ranging from 1(poor) to 5 (Excellent)

    Time frame: From the date of image reconstruction completion to the date of image evaluation completion, anticipated 3 Months.

  2. Objective image quality

    The objective image quality is evaluated by measuring the CT value shown in the image.

    Time frame: From the date reconstruction completion to the date of image evaluation completion, anticipated 3months.

07

Study locations

1 site
  • Sun Yat-sen cancer center
    Guangzhou, Guangdong, China
08

References and documents

Individual participant data

Plan to share: Undecided — Site and Sponsor need further discussion

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 2, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07620444
Lead sponsor
Philips Clinical & Medical Affairs Global
Collaborators
Sun Yat-Sen University Cancer Center
Responsible party
Sponsor
First posted
Jun 2, 2026
Start date
Jun 1, 2026 (estimated)
Primary completion
Dec 31, 2026 (estimated)
Completion
Dec 31, 2026 (estimated)
Last update
Jun 2, 2026

Study contacts

Miao Chuan Xie
Contact
xiechm@sysucc.org.cn
+8618903050011

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.

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