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CompletedNCT07604454Updated May 22, 2026

Muscle Energy Technique Combined With Mulligan Technique in Tennis Elbow

An interventional study of Muscle Energy Technique Combined With Mulligan Technique and Mulligan Mobilization With Movement in Lateral Epicondylitis and Tennis Elbow, sponsored by University of Lahore. Completed at 1 site in Pakistan. Open to participants aged 18 Years to 45 Years. Per ClinicalTrials.gov, last updated 2026-05-22.

Sponsored by University of Lahore · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 7 months after the study started (first participant enrolled Sep 2025, registered May 2026).
Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
18 Years to 45 Years
Sex
All
01

Study summary

This randomized controlled trial aims to evaluate the effectiveness of Muscle Energy Technique (MET) combined with Mulligan Mobilization With Movement (MWM) in patients with lateral epicondylitis (tennis elbow). The study compares the combined intervention with Mulligan technique and routine physical therapy alone. Outcomes including pain intensity, functional disability, and quality of life will be assessed using NPRS, PRTEE, and SF-8 questionnaires over a four-week treatment period.

Read the detailed description

Lateral epicondylitis, commonly known as tennis elbow, is a musculoskeletal disorder characterized by pain and reduced functional ability affecting the lateral aspect of the elbow. It commonly results from repetitive wrist extension and forearm movements leading to overuse of the extensor tendons.

Conservative physiotherapy management including manual therapy and therapeutic exercises is widely used for the treatment of lateral epicondylitis. Mulligan Mobilization With Movement (MWM) has shown beneficial effects in reducing pain and improving grip strength and functional mobility. Muscle Energy Technique (MET) is another manual therapy approach that may help improve joint mobility, muscle flexibility, and pain reduction through controlled isometric contractions.

This study aims to determine whether combining MET with Mulligan technique provides superior clinical outcomes compared to Mulligan technique alone in patients with tennis elbow.

Participants will be randomly allocated into two groups:

Experimental Group: MET + MWM + Routine Physical Therapy Control Group: MWM + Routine Physical Therapy

Treatment will be provided five sessions per week for four weeks. Outcomes will be assessed at baseline and after completion of the intervention period.

02

Conditions studied

  • Lateral Epicondylitis
  • Tennis Elbow

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Keywords

  • Tennis Elbow
  • Lateral Epicondylitis
  • Muscle Energy Technique
  • Mulligan Technique
  • Mobilization With Movement
03

In context

Tennis Elbow

284 studies on the registry are indexed under Tennis Elbow; 60 are open to participants now.

This study's enrollment of 40 is below the median of 50 across 253 interventional studies indexed under Tennis Elbow.

Browse Tennis Elbow studies →

Lead sponsor

University of Lahore is the lead sponsor of 223 studies on the registry; 40 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 45 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Age between 18 and 45 years
  • Both genders
  • Unilateral lateral epicondylitis
  • Diagnosed by senior physiotherapist
  • Pain duration of at least 6 weeks
  • Pain score ≥7 on NPRS/VAS
  • Positive symptoms during extensor carpi radialis brevis and longus isometric contraction

Exclusion criteria

Exclusion Criteria:

  • Previous elbow or shoulder surgery
  • Manual therapy within previous 6 months
  • History of fracture, dislocation, or tendon tear
  • Steroid or pain medication use
  • Peripheral nerve entrapment
  • Cervical radiculopathy
  • Osteoporosis or metastasis involving elbow
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
40 participants (actual)

Study arms

  • Experimental
    Experimental Group (MET + MWM + Routine Physical Therapy)

    Participants in this group will receive Muscle Energy Technique combined with Mulligan Mobilization With Movement along with routine physical therapy including eccentric strengthening and stretching exercises for wrist extensors.

    Procedure: Muscle Energy Technique Combined With Mulligan Technique

  • Active comparator
    Control Group (MWM + Routine Physical Therapy)

    Participants in this group will receive Mulligan Mobilization With Movement along with routine physical therapy including eccentric strengthening and stretching exercises.

    Procedure: Mulligan Mobilization With Movement

Interventions

  • ProcedureMuscle Energy Technique Combined With Mulligan Technique

    Muscle Energy Technique will be applied using resisted isometric contractions of forearm supination and pronation. Mulligan Mobilization With Movement will be applied using sustained lateral glide during pain-free gripping activity. Treatment sessions will be conducted five times weekly for four weeks.

  • ProcedureMulligan Mobilization With Movement

    Mulligan Mobilization With Movement technique will be applied using sustained glide of the forearm while participants perform pain-free gripping activities. Sessions will be conducted five times weekly for four weeks.

06

What researchers measure

Primary outcomes

  1. Pain Intensity Measured by Numeric Pain Rating Scale (NPRS)

    Pain intensity will be measured using the Numeric Pain Rating Scale (NPRS), an 11-point scale ranging from 0 (no pain) to 10 (worst imaginable pain).

    Time frame: Baseline and after 4 weeks of intervention

Secondary outcomes

  1. Functional Disability Measured by PRTEE Questionnaire

    Functional disability will be assessed using the Patient-Rated Tennis Elbow Evaluation (PRTEE) questionnaire.

    Time frame: Baseline and after 4 weeks of intervention

  2. Quality of Life Measured by SF-8 Questionnaire

    Quality of life will be assessed using the Short Form-8 (SF-8) questionnaire. The SF-8 is an 8-item questionnaire that evaluates physical functioning, general health, pain, vitality, social functioning, emotional role, mental health, and physical role limitations. Higher scores indicate better quality of life.

    Time frame: Baseline and after 4 weeks of intervention

07

Study locations

1 site
  • University of Lahore Teaching Hospital, Lahore
    Lahore, Punjab Province, Pakistan
08

References and documents

Publications

  • Bowman EN. Current concepts: pathology in the overhead athlete's lateral elbow. J Shoulder Elbow Surg. 2024 Feb;33(2):507-511. doi: 10.1016/j.jse.2023.08.017. Epub 2023 Sep 27. PubMed 37774828 ↗
  • Blanchette MA, Normand MC. Augmented soft tissue mobilization vs natural history in the treatment of lateral epicondylitis: a pilot study. J Manipulative Physiol Ther. 2011 Feb;34(2):123-30. doi: 10.1016/j.jmpt.2010.12.001. PubMed 21334545 ↗
  • Bazancir Z, Firat T. A potential factor in the pathophysiology of lateral epicondylitis: The long sarcomere length of the extensor carpi radialis brevis muscle and implications for physiotherapy. Med Hypotheses. 2019 Sep;130:109278. doi: 10.1016/j.mehy.2019.109278. Epub 2019 Jun 12. PubMed 31383324 ↗
  • Bagcaci S, Unuvar BS, Gercek H, Ugurlu I, Sert OA, Yilmaz K. A randomized controlled trial on pain, grip strength, and functionality in lateral elbow pain: Mulligan vs muscle energy techniques. J Back Musculoskelet Rehabil. 2023;36(2):419-427. doi: 10.3233/BMR-220061. PubMed 36120766 ↗
  • Alagaesan, J., & Nirmala, J. G. (2024). Effectiveness of Mulligan Mobilization Technique Versus Cyriax Technique for Lateral Epicondylitis: A Pilot Study. Indian Journal of Physiotherapy & Occupational Therapy, 18.
  • Akbar H, Akbar S, Saddique MN, Sarfraz MS. Prevalence of lateral epicondylitis among housewives in Lahore: a cross-sectional study. BMC Musculoskelet Disord. 2024 Oct 15;25(1):815. doi: 10.1186/s12891-024-07889-x. PubMed 39407258 ↗
  • Ahmed A, Ibrar M, Arsh A, Wali S, Hayat S, Abass S. Comparing the effectiveness of Mulligan mobilization versus Cyriax approach in the management of patients with subacute lateral epicondylitis. J Pak Med Assoc. 2021 Jan;71(1(A)):12-15. doi: 10.47391/JPMA.186. PubMed 33484510 ↗
  • Afzal, M., Zakaullah, S., Memon, S. I., Nisar, A., Touqeer, H., & Shabir, H. (2021). Prevalence and risk factors of lateral epicondylitis among restaurant cooks at district Gujranwala: A cross-sectional study. Rawal Medical Journal, 46(2), 338.
  • Aben A, De Wilde L, Hollevoet N, Henriquez C, Vandeweerdt M, Ponnet K, Van Tongel A. Tennis elbow: associated psychological factors. J Shoulder Elbow Surg. 2018 Mar;27(3):387-392. doi: 10.1016/j.jse.2017.11.033. PubMed 29433642 ↗
  • Abd Elrahim, R. M., Ali, M. F., Elwerdany, S. H., Salama, A. M., & Elsayed, M. (2022). Mulligan mobilisation with movement versus deep friction massage in patients with lateral epicondylitis. J Pharm Negat Results, 13, 5184-5192.

Individual participant data

Plan to share: No — Individual participant data will not be shared because this study was conducted as an academic research project. The informed consent obtained from participants did not include provisions for public data sharing, and the dataset contains sensitive personal health information. Data will be stored securely and used only for academic and research purposes in accordance with institutional ethics approval.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 22, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07604454
Lead sponsor
University of Lahore
Collaborators
University of Lahore Hospital (ULH)
Responsible party
Aman Zahra (Doctor of Physical Therapy Student, University of Lahore) — Principal investigator
First posted
May 22, 2026
Start date
Sep 26, 2025
Primary completion
Oct 28, 2025
Completion
Jan 25, 2026
Last update
May 22, 2026

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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