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Enrolling by invitationNCT07604155Updated May 22, 2026

Maxillary Sinus Augmentation Using CAD/CAM Allogenic Bone Blocks Versus Particulate Allogenic Grafts

An interventional study of sinus lifting using CAD/CAM allogenic block and sinus lifting using particulate allogenic graft in Maxillary Sinus and Allograft, sponsored by Tanta University. Enrolling by invitation at 1 site in Egypt. Open to participants aged 20 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-05-22.

Sponsored by Tanta University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 8 months after the study started (first participant enrolled Sep 2025, registered May 2026).
Phase
Not applicable
Study type
Interventional
Enrollment
28
Allocation
Randomized
Ages
20 Years and older
Sex
All
01

Study summary

28 patients will be included in this study with atrophic posterior maxillary ridge due to sinus pneumatization who will randomly assigned to two groups

  • Group I: sinus lifting using CAD/CAM allogenic block through lateral window technique
  • Group II: sinus lifting using particulate allogenic graftthrough lateral window technique
Read the detailed description

28patients will be included in this study with an atrophic posterior maxillary ridge due to sinus pneumatization, who will be randomly assigned to two groups

  • Group I: sinus lifting using CAD/CAM allogenic block through lateral window technique
  • Group II: sinus lifting using particulate allogenic graft through the lateral window technique
  • Surgical procedure: A full-thickness, wide mucoperiosteal flap was elevated buccally. Alateral bony window of the maxillary sinus will be made then the sinus lining will be elevated carefully. The CAD/CAM allogenic block will be inserted and fixed in its position via a titanium screw to the crest of maxillary ridge (group I). In group II the particulate bone will be packed at the site of augmentation
  • The lateral window will be covered with collagen membrane, the flap will reposited in its place and sutured.

    6 months later, implants will be inserted

02

Conditions studied

  • Maxillary Sinus
  • Allograft

Keywords

  • CAD-CAM allogenic block
  • particulate allograft
  • sinus lifting
03

In context

Lead sponsor

Tanta University is the lead sponsor of 963 studies on the registry; 304 are open to participants now.

Of its 16 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • above 20 years
  • ridge height less than or equal to 5 mm
  • healthy clear sinus

Exclusion criteria

Exclusion Criteria:

  • systemic disease affect bone healing
  • heavy smokers
  • disease or pathology within the sinus
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Triple (Participant, Investigator, Outcomes assessor)
Enrollment
28 participants (estimated)

Study arms

  • Experimental
    CAD/CAM allogenic block

    sinus lifting using CAD/CAM allogenic block through lateral window technique

    Procedure: sinus lifting using CAD/CAM allogenic block

  • Experimental
    particulate allogenic graft

    sinus lifting using particulate allogenic graft through lateral window technique

    Procedure: sinus lifting using particulate allogenic graft

Interventions

  • Proceduresinus lifting using CAD/CAM allogenic block

    A full-thickness, wide mucoperiosteal flap was elevated buccally. A lateral bony window of the maxillary sinus will be made, then the sinus lining will be carefully elevated. The CAD/CAM allogenic block will be inserted and fixed in its position via a titanium screw to the crest of maxillary ridge (group I). • The lateral window will be covered with collagen membrane, the flap will be repositioned in its place and sutured.

  • Proceduresinus lifting using particulate allogenic graft

    In group II the particulate bone will packed at the site of augmentation

06

What researchers measure

Primary outcomes

  1. bone height gain

    using CBCT

    Time frame: 6 months

  2. marginal bone resorption around implants

    CBCT

    Time frame: 6 months

07

Study locations

1 site
  • Faculty of Dentistry, Tanta University
    Tanta, 3111, Egypt
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 22, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07604155
Lead sponsor
Tanta University
Responsible party
mona samy sheta (lecturer of oral and maxillofacial surgery, Tanta University) — Principal investigator
First posted
May 22, 2026
Start date
Sep 3, 2025
Primary completion
Dec 10, 2026 (estimated)
Completion
Mar 19, 2027 (estimated)
Last update
May 22, 2026

Study contacts

mohamed h helal, lecturer
principal investigator · Tanta University
rehab ghouraba, professor
principal investigator · Tanta University

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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