CClinicalTrials.gg
Not yet recruitingNCT07597135Updated May 19, 2026

Comparative Evaluation of Alb PRF Versus Connective Tissue Graft in Reconstruction of Deficient Interdental Papilla

A Phase 3 interventional study of Albumin (5% serum-protein solution containing immunoglobulins) and connective tissue graft in Deficient Interdental Papilla, sponsored by ahmed mostafa ahmed abo el soud. Not yet recruiting. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-05-19.

Sponsored by ahmed mostafa ahmed abo el soud · Phase 3, Interventional, and Treatment

Phase
Phase 3
Study type
Interventional
Enrollment
28
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

This study will evaluate the efficacy of Alb PRF membrane in comparison to a subepithelial connective tissue graft in the reconstruction of interdental papillae.

Read the detailed description

the reconstruction will be done using the Hans Taki surgical technique, while Alb PRF will be used as a membrane.

02

Conditions studied

  • Deficient Interdental Papilla

Keywords

  • interdental papilla
03

In context

Lead sponsor

This is the only study on the registry with ahmed mostafa ahmed abo el soud as lead sponsor.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • inter dental papilla deficincy

Exclusion criteria

Exclusion Criteria:

  • smokers
05

Study design

Phase
Phase 3
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
28 participants (estimated)

Study arms

  • Active comparator
    connective tissue graft

    Biological: connective tissue graft

  • Experimental
    Albumin plasma rich fibrin membrane

    Biological: Albumin (5% serum-protein solution containing immunoglobulins)

Interventions

  • BiologicalAlbumin (5% serum-protein solution containing immunoglobulins)

    a variation of PRF done by heating up to 75 degree then mixed with the remaining prf to get membrane

  • Biologicalconnective tissue graft

    subepithelial connective tissue graft

06

What researchers measure

Primary outcomes

  1. papillary height measured from apical part of contact point to tip of papilla (CP-TP)

    Time frame: from enrollment, 3 months, 6months, 9months, 12months

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 19, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07597135
Lead sponsor
ahmed mostafa ahmed abo el soud
Responsible party
ahmed mostafa ahmed abo el soud (doctor, Cairo University) — Sponsor-investigator
First posted
May 19, 2026
Start date
Jun 20, 2026 (estimated)
Primary completion
Sep 20, 2028 (estimated)
Completion
Dec 20, 2028 (estimated)
Last update
May 19, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in May 2026. You cannot join it, but the record below documents what was studied.

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