CClinicalTrials.gg
Not yet recruitingNCT07595406CERVESPUpdated May 19, 2026

Cervical Medial Branch Block Versus Ipsilateral Cervical Erector Spinae Plane Block

An interventional study of Ultrasound-guided cervical medial branch block and Ultrasound-guided cervical erector spinae plane block in Cervical Facetogenic Pain, Chronic Neck Pain and Cervical Facet Joint Syndrome, sponsored by Ankara City Hospital Bilkent. Not yet recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-05-19.

Sponsored by Ankara City Hospital Bilkent · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
130
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

This prospective randomized controlled study aims to compare the analgesic effectiveness of ultrasound-guided cervical medial branch block and ipsilateral cervical erector spinae plane block in patients with cervical facetogenic pain.

Patients with chronic cervical facet-mediated pain will be randomized into two intervention groups. Pain intensity, functional status, meaningful pain response rates, analgesic consumption, and patient satisfaction will be evaluated during follow-up.

The primary objective is to determine whether cervical erector spinae plane block provides comparable short-term pain relief to cervical medial branch block.

Read the detailed description

Cervical facet joints are an important source of chronic axial neck pain. Diagnostic cervical medial branch block is commonly used to identify facet-mediated pain and may also provide short-term analgesic benefit. However, this procedure requires precise targeting of the cervical medial branches and may be technically demanding in some patients.

The cervical erector spinae plane block is an ultrasound-guided interfascial plane block that may provide analgesia through cranio-caudal spread of local anesthetic along the paraspinal fascial plane. Although it has been increasingly used for perioperative and chronic pain indications, its role in cervical facetogenic pain has not been clearly established.

This study will compare the short-term analgesic effectiveness of ultrasound-guided cervical medial branch block and ipsilateral cervical erector spinae plane block in patients with clinically suspected cervical facetogenic pain. Eligible patients will be randomized to receive one of the two ultrasound-guided interventions. Pain intensity, functional disability, meaningful pain response, analgesic use, patient satisfaction, and procedure-related adverse events will be assessed during follow-up.

The study is designed to determine whether cervical erector spinae plane block can provide clinically meaningful pain relief comparable to cervical medial branch block in this patient population.

02

Conditions studied

  • Cervical Facetogenic Pain
  • Chronic Neck Pain
  • Cervical Facet Joint Syndrome
03

In context

Lead sponsor

Ankara City Hospital Bilkent is the lead sponsor of 424 studies on the registry; 105 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Age between 18 and 80 years
  • Chronic neck pain lasting at least 3 months
  • Clinical findings suggestive of cervical facetogenic pain
  • Numeric Rating Scale pain score ≥4
  • Ability to provide informed consent

Exclusion criteria

Exclusion Criteria:

  • Cervical radiculopathy or myelopathy
  • Major neurological deficit
  • Infection at the injection site
  • Coagulopathy or anticoagulant therapy contraindicating intervention
  • Allergy to local anesthetics
  • Pregnancy
  • Previous cervical interventional pain procedure within the last 3 months
  • Severe psychiatric disease
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
130 participants (estimated)

Study arms

  • Experimental
    Cervical Medial Branch Block

    Ultrasound-guided cervical medial branch block will be performed at the clinically suspected symptomatic cervical facet levels.

    Other: Ultrasound-guided cervical medial branch block

  • Experimental
    Cervical Erector Spinae Plane Block

    Ultrasound-guided ipsilateral cervical erector spinae plane block will be performed at the symptomatic cervical level. I

    Other: Ultrasound-guided cervical erector spinae plane block

Interventions

  • OtherUltrasound-guided cervical medial branch block

    Ultrasound-guided cervical medial branch block performed at clinically suspected symptomatic cervical facet levels using local anesthetic for diagnostic and analgesic purposes.

  • OtherUltrasound-guided cervical erector spinae plane block

    Ultrasound-guided ipsilateral cervical erector spinae plane block performed at the symptomatic cervical level using local anesthetic for analgesic purposes.

06

What researchers measure

Primary outcomes

  1. Meaningful Pain Response

    Proportion of patients achieving at least 50% reduction in Numeric Rating Scale (NRS) pain score during the early post-procedural period.

    Time frame: Time Frame: 1 hour after the procedure

Secondary outcomes

  1. NRS24

    Change in pain intensity measured using the 11-point Numeric Rating Scale (0=no pain, 10=worst imaginable pain).

    Time frame: at 24 Hours

  2. NRS1

    Change in pain intensity measured using the 11-point Numeric Rating Scale.( 0=no pain, 10=worst imaginable pain)

    Time frame: 1 week after the procedure

  3. NDI

    Functional disability associated with neck pain assessed using the Neck Disability Index.0 = no disability 50 = complete disability Higher scores indicate greater neck-related functional disability (worse outcome).

    Time frame: Baseline and 1 week after the procedure

  4. GPE

    Patient-reported global improvement evaluated using a 7-point Global Perceived Effect scale. The GPE scale ranges from -5 to +5, where: -5 = vastly worse 0 = no change +5 = completely recovered

    Time frame: 1 week after the procedure

  5. Analgesic Consumption

    Need for rescue analgesic medication after the procedure.

    Time frame: 24 hours and 1 week after the procedure

  6. Patient Satisfaction

    Patient satisfaction regarding the procedure.

    Time frame: 1 week after the procedure

  7. Complications

    Procedure-related adverse events and complications.

    Time frame: Perioperative/Periprocedural

07

Study locations

1 site
  • Ankara Bilkent City Hospital
    Ankara, Ankara 06680, Turkey (Türkiye)
08

References and documents

Publications

  • Elsharkawy H, Ince I, Hamadnalla H, Drake RL, Tsui BCH. Cervical erector spinae plane block: a cadaver study. Reg Anesth Pain Med. 2020 Jul;45(7):552-556. doi: 10.1136/rapm-2019-101154. Epub 2020 Apr 21. PubMed 32321860 ↗

Individual participant data

Plan to share: Undecided

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 19, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07595406
Lead sponsor
Ankara City Hospital Bilkent
Responsible party
Ülkü Sabuncu (Assoc Prof, Ankara City Hospital Bilkent) — Principal investigator
First posted
May 19, 2026
Start date
May 31, 2026 (estimated)
Primary completion
Sep 30, 2026 (estimated)
Completion
Dec 31, 2026 (estimated)
Last update
May 19, 2026

Study contacts

Ülkü Sabuncu, Assoc prof
Contact
sabuncuulku@gmail.com
905337085212

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in May 2026. You cannot join it, but the record below documents what was studied.

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