An interventional study of General Anesthesia and cervical plexus block in General Anesthesia, Cervical Plexus Block and Thyroid Surgery, sponsored by Harran University. Not yet recruiting. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2026-05-18.
Sponsored by Harran University · Not applicable, Interventional, and Treatment
The main aim of this study is to compare the effects of two different anesthesia methods-(1) general anesthesia alone and (2) combination of general anesthesia with cervical plexus block-on postoperative inflammatory process and amino acid metabolism in patients undergoing thyroidectomy.
Harran University is the lead sponsor of 60 studies on the registry; 21 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
THIS GROUP WILL INCLUDE PATIENTS WHO ARE UNDER GENERAL ANESTHESIA.
Procedure: cervical plexus block
IN THIS GROUP, CERVICAL PLEXUS BLOCK WILL BE PERFORMED IN ADDITION TO GENERAL ANESTHESIA.
Procedure: General Anesthesia
In our study, one patient group will receive only general anesthesia, while the other group will receive general anesthesia in addition to ultrasound-guided cervical plexus block. The inflammatory response is a natural response of the body's immune system to surgical trauma, and it can vary depending on the anesthetic agent used. In regulating this response, molecules such as IL-1β, TNF-α, IL-6, IL-10, and IL-40 are important indicators that determine the severity and duration of inflammation. These parameters will be examined and compared in both groups.
In our study, one patient group will receive only general anesthesia, while the other group will receive general anesthesia in addition to ultrasound-guided cervical plexus block.
Perioperative Inflammatory Response
IL-1β, TNF-α, IL-6, IL-10, and IL-40 levels will be measured 1 hour before surgery, and then 2 and 6 hours after surgery, and these values will then be compared.
Time frame: Before the procedure, and at 2 and 6 hours after the procedure.
Inflammatory Response
IL-1β, TNF-α, IL-6, IL-10, and IL-40 levels will be measured 1 hour before surgery, and then 2 and 6 hours after surgery, and these values will then be compared.
Time frame: Before the procedure, and at 2 and 6 hours after the procedure.
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in May 2026. You cannot join it, but the record below documents what was studied.
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Harran University