An observational study in Liver Cirrhosis and Portal Vein Thrombosis, sponsored by Elham Ahmed Hassan. Active, not recruiting at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-05-01.
Sponsored by Elham Ahmed Hassan · Observational
Portal vein thrombosis (PVT) is a common complication in patients with liver cirrhosis and is associated with increased morbidity due to worsening portal hypertension and hepatic decompensation. The clinical presentation and radiological patterns of PVT vary widely, and the factors predicting its development remain incompletely understood.
This observational study will include adult patients (≥18 years) with established liver cirrhosis who are admitted to the Department of Gastroenterology and Tropical Medicine, Al-Rajhi Liver Hospital, Assiut University. Eligible participants will undergo routine screening for PVT using Doppler ultrasonography, with confirmation by contrast-enhanced computed tomography when indicated.
The study aims to evaluate the clinical characteristics, laboratory parameters, and radiological features of PVT. Cases of PVT will be classified according to extent (partial or complete) and anatomical location (main portal vein, right branch, left branch, or combined involvement). Clinical and laboratory data will be analyzed to identify potential predictors associated with the development and severity of PVT.
The findings of this study are expected to improve understanding of the risk factors and radiological patterns of PVT in cirrhotic patients, contributing to better risk stratification and clinical management.
1,642 studies on the registry are indexed under Liver Cirrhosis; 358 are open to participants now.
This study's enrollment of 240 is above the median of 151 across 587 observational studies indexed under Liver Cirrhosis.
Browse Liver Cirrhosis studies →Elham Ahmed Hassan is the lead sponsor of 2 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Adult patients with liver cirrhosis
Exclusion Criteria:
Diagnostic Test: Abdominal US, Doppler US and abdominal multi-slice computed tomography (MSCT) with contrast was performed
to assess portal circulation, portosystemic collaterals, the presence of PVT, ascites and HCC.
Prevalence of Portal Vein Thrombosis (PVT)
Proportion of cirrhotic patients diagnosed with portal vein thrombosis based on Doppler ultrasonography with confirmation by contrast-enhanced CT when indicated.
Time frame: At baseline (during study enrollment period)
Predictors of Portal Vein Thrombosis
Identification of clinical, laboratory, and radiological factors associated with the presence of PVT in cirrhotic patients
Time frame: Baseline assessment
Radiological Pattern of PVT
Distribution of portal vein thrombosis according to: Extent (partial vs complete) Anatomical location (main portal vein, right branch, left branch, or combined involvement)
Time frame: At time of PVT diagnosis
Association Between PVT Type and Clinical Parameters
Correlation between type of PVT (partial vs complete) and clinical/laboratory characteristics of patients.
Time frame: At time of diagnosis
Plan to share: No — I do not have specific consent from participants to share individual-level data.
No publications or documents are linked to this record.
This study is active, not recruiting, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.
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Elham Ahmed Hassan