ClinicalTrials.gg
Active, not recruitingNCT07551193Updated Apr 24, 2026

Evaluating Weight Loss Outcomes in Patients With Overweight or Obesity

An observational study in Overweight and Obesity, sponsored by Aldafter Medical Center, Bahrain. Active, not recruiting at 1 site in Bahrain. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-04-24.

Primary conditionObesityRegistry: OverweightReclassifiedWhy we changed it
Registry
Overweight — the first condition term the registry derived for this study.
ClinicalTrials.gg
Obesity
Why
  1. The study's listed conditions name Obesity, a narrower term within Overweight.
Confidence
High: the new condition is named in the study's own listed conditions. Of 351 hand-checked studies reclassified this way, 68% were exactly right and 84% in the right disease family; the registry's first term was right for 5% (measured 2026-10-21). How we classify →
Wrong?
Tell us the study's main condition →

Sponsored by Aldafter Medical Center, Bahrain · Observational

From the registry’s dates

  • Primary completion was expected by Jun 2026, 4 months ago, but the record still lists the study as active, not recruiting.
Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
300
Ages
18 Years and older
Sex
All
01

Study summary

The goal of this observational study is to evaluate weight loss outcomes in adults with overweight or obesity using weight management medications. The main questions it aims to answer are: (1) How much weight do patients lose after 12 months? (2) Do blood sugar and cholesterol levels improve? (3) How safe and tolerable are these medications? This is a retrospective study using existing medical records and pharmacy claims. Participants will not be asked to do anything new; all data will be collected from routine clinical care.

Read the detailed description

The goal of this observational study is to learn how much weight adults with overweight or obesity lose after taking weight management for 12 months. The study also aims to learn whether these medications improve blood sugar and cholesterol levels, and how safe and tolerable they are.

The main questions it aims to answer are:

How much weight (in kilograms and percentage) do patients lose after 12 months of treatment? Do patients' fasting blood sugar, HbA1c, and cholesterol levels improve after 12 months? What side effects or treatment discontinuations occur in routine clinical practice? Researchers will compare weight loss outcomes among different patient groups based on age, sex, baseline BMI, and the specific medication used.

This is a retrospective study, meaning participants will not be asked to do anything new. Researchers will collect information from existing medical records and pharmacy claims at Aldafter Medical Center (ADMC) in Bahrain, including weight measurements, lab results, and medication histories from routine clinical care.

02

Conditions studied

  • Overweight and Obesity

Browse trials for

Keywords

  • obesity
03

In context

Obesity Reclassified

11,522 studies on the registry are indexed under Obesity; 2,033 are open to participants now.

This study's planned enrollment of 300 is above the median of 114 across 2,154 observational studies indexed under Obesity.

Browse Obesity studies →

Lead sponsor

This is the only study on the registry with Aldafter Medical Center, Bahrain as lead sponsor.

Compared within Obesity, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Overweight. The counts are of registry records indexed under each term, refreshed daily. How we classify →

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult patients (≥18 years) with overweight or obesity (BMI ≥25) who received weight management medications. Patients must have continuous insurance enrollment for 12 months before and after treatment initiation, and weight measurements at both baseline and 12 months.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Age: Adults aged 18 years or older.
  2. (BMI): Patients classified as overweight (BMI 25-29.9 kg/m²) or obese (BMI ≥30 kg/m²).
  3. Medication: At least one pharmacy claim for any approved weight management medication
  4. Continuous Enrollment: Patients must have continuous enrollment in medical and pharmacy insurance for 1 year prior to the index date (date of treatment initiation) and 1 year afterward.

    -

Exclusion criteria

Exclusion Criteria:

  1. Type 1 Diabetes: Patients with a diagnosis of type 1 diabetes.
  2. Non-Compliance: Evidence of non-compliance with treatment (e.g., gaps in therapy greater than 30 days).
  3. Bariatric Surgery: Patients who have undergone bariatric surgery in the past 5 years.
  4. Serious Comorbidities: Presence of serious medical conditions that may confound weight loss outcomes (e.g., uncontrolled psychiatric disorders, cancer).
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
300 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Absolute Weight Change

    Absolute weight change (kg) from baseline to 12 months

    Time frame: Baseline to 12 months

07

Study locations

1 site
  • AlDafter Medical center
    Manama, Bahrain
08

References and documents

Individual participant data

Plan to share: No — Individual participant data (IPD) will not be shared with other researchers. Only de-identified aggregate results will be published.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 24, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07551193
Lead sponsor
Aldafter Medical Center, Bahrain
Responsible party
Huda Omran (Specialist, Aldafter Medical Center, Bahrain) — Principal investigator
First posted
Apr 24, 2026
Start date
Oct 25, 2025
Primary completion
Jun 25, 2026 (estimated)
Completion
Oct 30, 2026 (estimated)
Last update
Apr 24, 2026

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion