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CompletedNCT07544485LOW-ST-SDUpdated Apr 24, 2026

Ultrasound-Guided Low-Volume Brachial Plexus Block in the Supraclavicular Region for Shoulder Reduction in the Emergency Department

An observational study in Shoulder Dislocation and Joint Dislocation, sponsored by Merian Iselin Klinik. Completed at 1 site in Switzerland. Open to participants aged 15 Years and older. Per ClinicalTrials.gov, last updated 2026-04-24.

Sponsored by Merian Iselin Klinik · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
206
Ages
15 Years and older
Sex
All
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Study summary

Acute shoulder dislocation is a common and painful condition in the emergency department (ED). Procedural sedation is widely used to facilitate reduction but is associated with potential risks and resource use. Ultrasound-guided regional anesthesia has emerged as an alternative approach.

This retrospective, monocentric observational study analyzes routinely collected clinical data from an orthopedic ED between February 2018 and February 2024. Adult patients with acute shoulder dislocation are included.

The study evaluates the feasibility, safety, and clinical implementation of low-volume (approximately 5 ml local anesthetic) ultrasound-guided brachial plexus block in the supraclavicular region. Outcomes include procedural success, block-related complications, and temporal trends reflecting the adoption of the technique over time.

Read the detailed description

Acute shoulder dislocation is a frequent orthopedic emergency requiring timely reduction. Procedural sedation and analgesia (PSA) is commonly used but may be associated with risks and increased resource utilization. Ultrasound-guided regional anesthesia of the brachial plexus represents an alternative approach that may allow effective reduction without systemic sedation.

This retrospective, monocentric observational study is based on routinely collected clinical data from the orthopedic emergency department of the Merian Iselin Klinik Basel, Switzerland, covering the period from February 2018 to February 2024. All eligible patients with acute shoulder dislocation were included.

During the study period, ultrasound-guided low-volume brachial plexus block in the supraclavicular region was progressively implemented as part of routine clinical practice. The technique used a standardized low-volume approach (approximately 5 ml local anesthetic).

The aim of this study is to evaluate the feasibility and safety of this approach in a real-world setting, as well as to describe its implementation over time. Particular focus is placed on procedural success, block-related complications, and temporal trends reflecting increasing use and operator experience.

The study further explores the practical aspects of integrating this technique into routine emergency care, including its applicability across a broader group of physicians in a setting with rotating staff and limited case numbers.

The study is conducted in accordance with the Swiss Human Research Act (HRA) as a further use of health-related personal data without consent (Art. 34 HRA). All data are analyzed in coded form without additional interventions or patient contact.

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Conditions studied

  • Shoulder Dislocation
  • Joint Dislocation

Keywords

  • Ultrasound-guided regional anesthesia
  • Brachial plexus block
  • Low-volume nerve block
  • Supraclavicular approach
  • Shoulder reduction
  • Emergency department
  • Procedural sedation
  • Retrospective study
  • Implementation
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In context

Shoulder Dislocation

105 studies on the registry are indexed under Shoulder Dislocation; 22 are open to participants now.

This study's enrollment of 206 is above the median of 86 across 28 observational studies indexed under Shoulder Dislocation.

Browse Shoulder Dislocation studies →

Lead sponsor

This is the only study on the registry with Merian Iselin Klinik as lead sponsor.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
15 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Patients presenting with acute shoulder dislocation to a specialized orthopedic emergency department in a single-center setting.

The study population reflects routine clinical practice, including patients treated with ultrasound-guided brachial plexus block or alternative approaches.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients presenting with acute shoulder dislocation to the orthopedic emergency department of the Merian Iselin Klinik Basel between February 2018 and February 2024.
  • Patients treated within routine clinical care with documented management of shoulder reduction.

Exclusion criteria

Exclusion Criteria:

  • Patients with incomplete or missing clinical documentation relevant to the study endpoints.
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
206 participants (actual)
Patient registry
No

Groups and cohorts

  • Patients with acute shoulder dislocation

    Adult patients presenting with acute shoulder dislocation to the orthopedic emergency department between February 2018 and February 2024. Patients were treated according to routine clinical practice, including ultrasound-guided low-volume brachial plexus block or alternative approaches.

    Procedure: Ultrasound-guided brachial plexus block

Interventions

  • ProcedureUltrasound-guided brachial plexus block

    Ultrasound-guided low-volume brachial plexus block performed in the supraclavicular region as part of routine clinical care for shoulder reduction. The technique was applied according to operator experience and evolving clinical practice over time.

    Also known as: Low-volume nerve block, Supraclavicular approach

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What researchers measure

Primary outcomes

  1. Successful shoulder reduction without procedural sedation

    Proportion of patients in whom shoulder reduction was successfully achieved using ultrasound-guided low-volume brachial plexus block without conversion to procedural sedation or general anesthesia.

    Time frame: During the emergency department visit

Secondary outcomes

  1. Block-related complications

    Occurrence of complications associated with ultrasound-guided brachial plexus block as documented in routine clinical records.

    Time frame: During the emergency department visit

  2. Conversion to procedural sedation

    Proportion of cases requiring conversion to procedural sedation after initial attempt with regional anesthesia.

    Time frame: During the emergency department visit

  3. Temporal trends in technique utilization

    Change in the proportion of patients treated with ultrasound-guided brachial plexus block over time, reflecting adoption of the technique and increasing operator experience.

    Time frame: February 2018 to February 2024

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Study locations

1 site
  • Merian Iselin Klinik, Orthopaedic Emergency Department
    Basel, Basel 4009, Switzerland
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References and documents

Publications

  • Schöll E, Litz RJ, et al. Ultrasound-guided brachial plexus block for shoulder reduction. Presented at the Dreiländertreffen der SGUM/DEGUM/ÖGUM, 2024. DOI: 10.1055/s-0044-1789060
  • Zacchilli MA, Owens BD. Epidemiology of shoulder dislocations presenting to emergency departments in the United States. J Bone Joint Surg Am. 2010 Mar;92(3):542-9. doi: 10.2106/JBJS.I.00450. PubMed 20194311 ↗
  • Leroux T, Wasserstein D, Veillette C, Khoshbin A, Henry P, Chahal J, Austin P, Mahomed N, Ogilvie-Harris D. Epidemiology of primary anterior shoulder dislocation requiring closed reduction in Ontario, Canada. Am J Sports Med. 2014 Feb;42(2):442-50. doi: 10.1177/0363546513510391. Epub 2013 Nov 25. PubMed 24275862 ↗
  • Blaivas M, Lyon M. Ultrasound-guided interscalene block for shoulder dislocation reduction in the ED. Am J Emerg Med. 2006 May;24(3):293-6. doi: 10.1016/j.ajem.2005.10.004. PubMed 16635700 ↗
  • Kanji A, Atkinson P, Fraser J, Lewis D, Benjamin S. Delays to initial reduction attempt are associated with higher failure rates in anterior shoulder dislocation: a retrospective analysis of factors affecting reduction failure. Emerg Med J. 2016 Feb;33(2):130-3. doi: 10.1136/emermed-2015-204746. Epub 2015 Jun 25. PubMed 26113487 ↗
  • Dimakopoulos P, Panagopoulos A, Kasimatis G, Syggelos SA, Lambiris E. Anterior traumatic shoulder dislocation associated with displaced greater tuberosity fracture: the necessity of operative treatment. J Orthop Trauma. 2007 Feb;21(2):104-12. doi: 10.1097/BOT.0b013e3180316cda. PubMed 17304065 ↗
  • Dunn MJ, Mitchell R, Souza CD, Drummond G. Evaluation of propofol and remifentanil for intravenous sedation for reducing shoulder dislocations in the emergency department. Emerg Med J. 2006 Jan;23(1):57-8. doi: 10.1136/emj.2004.021410. PubMed 16373806 ↗
  • Diego EBD, Diego ABD, Alcaraz AM, Tomás SN. Experience with regional anesthesia for reduction of shoulder dislocation in the emergency department.
  • Underhill TJ, Wan A, Morrice M. Interscalene brachial plexus blocks in the management of shoulder dislocations. Arch Emerg Med. 1989 Sep;6(3):199-204. doi: 10.1136/emj.6.3.199. PubMed 2789584 ↗
  • Tezel O, Kaldirim U, Bilgic S, Deniz S, Eyi YE, Ozyurek S, Durusu M, Tezel N. A comparison of suprascapular nerve block and procedural sedation analgesia in shoulder dislocation reduction. Am J Emerg Med. 2014 Jun;32(6):549-52. doi: 10.1016/j.ajem.2014.02.014. Epub 2014 Feb 17. PubMed 24721024 ↗
  • Blaivas M, Adhikari S, Lander L. A prospective comparison of procedural sedation and ultrasound-guided interscalene nerve block for shoulder reduction in the emergency department. Acad Emerg Med. 2011 Sep;18(9):922-7. doi: 10.1111/j.1553-2712.2011.01140.x. Epub 2011 Aug 30. PubMed 21883635 ↗
  • Raeyat Doost E, Heiran MM, Movahedi M, Mirafzal A. Ultrasound-guided interscalene nerve block vs procedural sedation by propofol and fentanyl for anterior shoulder dislocations. Am J Emerg Med. 2017 Oct;35(10):1435-1439. doi: 10.1016/j.ajem.2017.04.032. Epub 2017 Apr 14. PubMed 28460809 ↗
  • Harley JD, Harrison AK, Rao AJ. An update on regional anesthesia in shoulder surgery: a narrative review. Ann Jt. 2025 Jun 30;10:29. doi: 10.21037/aoj-24-64. eCollection 2025. PubMed 40791904 ↗
  • Sonawane K. Implementing Precision Regional Anesthesia in an Emergency Setting: Bilateral Upper Trunk Blocks for Shoulder Reduction. Cureus. 2025 Nov 26;17(11):e97859. doi: 10.7759/cureus.97859. eCollection 2025 Nov. PubMed 41312066 ↗
  • Schöll E, Gratza SK, Litz RJ. Bilaterale low-volume Blockade des Plexus brachialis bei beidseitiger antero-inferiorer Schulterluxation. Ultraschall Med - Eur J Ultrasound. September 2024;45(S 01):S42-S42.

Individual participant data

Plan to share: No — Data are not publicly available due to data protection regulations.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 24, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07544485
Lead sponsor
Merian Iselin Klinik
Collaborators
Bethesda Krankenhaus
Responsible party
Sponsor
First posted
Apr 22, 2026
Start date
Feb 5, 2018
Primary completion
Feb 28, 2024
Completion
Feb 28, 2024
Last update
Apr 24, 2026

Study contacts

Eckehart Schöll, MD
principal investigator · Bethesda Spital, Basel, Switzerland
Markus Knupp, MD
principal investigator · Merian Iselin Klinik, Basel, Switzerland

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.

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