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CompletedNCT07513597Updated Apr 7, 2026

Assessment of the Effects of a Daily Supplement 4Life Transfer Factor Vista Containing AREDS2 Formula on Skin Carotenoid Levels Using a Non-invasive Detection

An interventional study of Dietary Supplement in Skin Carotenoids, sponsored by 4Life Research, LLC. Completed at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-04-07.

Sponsored by 4Life Research, LLC · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 5 months after the study started (first participant enrolled Oct 2025, registered Mar 2026).
Phase
Not applicable
Study type
Interventional
Enrollment
24
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Study summary

The goal of the clinical study is to evaluate the impact of daily use of a dietary supplement TF Vista containing AREDS2 formula ingredients, astaxanthin (Haematococcus pluvialis) microalgae, bilberry (Vaccinium myrtillus) fruit powder and black currant (Ribes nigrum) fruit powder organic on skin carotenoid levels over an 8-week period for a Cohort 1(n= 20 participants) and 12 weeks for a Cohort 2 (n= 4 participants). Results will be compared using two devices - the Veggie Meter and the Samsung Watch - both of which utilize reflection spectroscopy technology. For Cohort 2 (n = 4 participants), in addition to assessing skin carotenoid levels, the study will also evaluate changes in macular pigment optical density (MPOD) before and after supplementation.

02

Conditions studied

  • Skin Carotenoids
03

In context

Lead sponsor

4Life Research, LLC is the lead sponsor of 6 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Healthy subjects ≥ 18 years of age. Committed to maintain the same eating, exercise, and other lifestyle routines for the whole duration of the study.

Exclusion criteria

Exclusion Criteria:

    • Pregnant and/or lactating women or planning to become pregnant in the following 12 weeks.
  • Participants were not allowed to participate if they have a known allergy or adverse reaction to any of the ingredients in the study product.
  • Participants were not allowed to participate if they have used AREDS2 formula products over the past 6 months.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
24 participants (actual)

Study arms

  • Experimental
    4lLife TF Vista

    Participants were supplied with two bottles of the study product (for Cohort-1) and three bottles (for Cohort-2) labeled with the participant number during the study. They were required to take the product consisting of 4 capsules per day, taken with 8 oz. of fluid and preferably with a meal.

    Other: Dietary Supplement

Interventions

  • OtherDietary Supplement

    Study product 4Life TF Vista contains Tri Factor (bovine colostrum and egg yolk), bilberry (Vaccinium myrtillus) fruit powder, black currant (Ribes Nigrum) powder, lutein, zeaxanthin (Tagetes erecta), vitamin C, vitamin A, vitamin E, zinc, and copper.

06

What researchers measure

Primary outcomes

  1. Skin Carotenoid Levels

    Skin carotenoid levels measured via a portable Veggie Meter, Longevity Link Corp. device using reflection spectroscopy on a participant's fingerprint.

    Time frame: From enrollment to the end of treatment at 8 weeks for Cohort-1 and 12 weeks for Cohort-2

Secondary outcomes

  1. Antioxidant Levels

    Antioxidant levels assessed by a Samsung Watch device via skin absorption spectra. The bioactive sensor measures reflected light after emitting LED light. The test requires the participant to press the thumb on the sensor for a few seconds to get a reading.

    Time frame: From enrollment to the end of treatment at 8 weeks for Cohort-1 and 12 weeks for Cohort-2.

Other outcomes

  1. Macular Pigment Optical Density (MPOD)

    Macular Pigment Optical Density (MPOD) testing measurement of the density of the light-absorbing pigments in the center of the retina. This tests is performed only for participants in Cohort-2.

    Time frame: At enrollment and at the end of the treatment (week-12)

  2. Visual Acuity Test

    Visual Acuity Test to measure sharpest vision using a Snellen eye chart, to determine the smallest detail a participant can see from 20 feet distance. Test will be performed only for participants included in Cohort-1

    Time frame: From enrollment to the end of treatment at 8 weeks.

  3. Amsler Grid Chart Test

    Amsler Grid Chart Test to monitor central vision for changes like way, blurry, or missing lines. Test performed only on participants included in Cohort-1.

    Time frame: From enrollment to the end of treatment at 8 weeks.

  4. Visual Functioning Questionnaire-25 (VFQ-25)

    Visual Functioning Questionnaire-25 (VFQ-25) to assess participants self-reported vision- related quality of life. For participants included in Cohort-1.

    Time frame: From enrollment to the end of treatment at 8 weeks.

07

Study locations

1 site
  • 4Life Research
    Sandy City, Utah 84070, United States
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 7, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07513597
Lead sponsor
4Life Research, LLC
Responsible party
Sponsor
First posted
Apr 7, 2026
Start date
Oct 16, 2025
Primary completion
Dec 17, 2025
Completion
Feb 14, 2026
Last update
Apr 7, 2026

Study contacts

David Vollmer
principal investigator · 4Life Research

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Mar 2026. You cannot join it, but the record below documents what was studied.

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