An interventional study of Group A - Fixed Pillow and Group B - Customized Pillow in Elective Surgery and General Anesthesia, sponsored by Shaheed Mohtarma Benazir Bhutto Institue of Trauma. Enrolling by invitation at 1 site in Pakistan. Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-16.
Sponsored by Shaheed Mohtarma Benazir Bhutto Institue of Trauma · Not applicable, Interventional, and Device feasibility
The goal of this clinical trial is to find out whether the ramp position or sniffing position is better for endo tracheal intubation which provides better hemodynamic stability and short intubation time and good laryngoscopic view in regards of cormack lehane grading.
This randomized controlled trial will be conducted at the Shaheed Mohtarma Benazir Bhutto Institute of Trauma after obtaining approval from the College of Physicians and Surgeons of Pakistan (CPSP) and the Ethical Review Committee. The study will also be registered on ClinicalTrials.gov prior to participant enrollment.
Participants will be allocated into two groups using computer-generated randomization. Group A will undergo tracheal intubation in the sniffing position using a fixed pillow height of 4 cm, while Group B will be positioned in the ramp position using a customized pillow height (4-8 cm) adjusted to achieve alignment of the external auditory meatus with the sternal notch. Allocation will be performed by the primary investigator prior to surgery.
All patients will receive a standardized anesthesia protocol with continuous ASA monitoring. Induction of anesthesia will be achieved using propofol (2 mg/kg) and nalbuphine (0.15 mg/kg), followed by atracurium (0.5 mg/kg) after confirmation of adequate mask ventilation. Controlled positive pressure ventilation will be maintained for three minutes before direct laryngoscopy using a Macintosh laryngoscope.
Laryngoscopy will be performed by the primary investigator, while a second anesthetist, blinded to the study objectives where feasible, will record procedural timings and hemodynamic parameters. Any adjuncts or optimization maneuvers used during intubation will be documented. Hemodynamic variables will be monitored at predefined intervals following intubation.
The study will be conducted as an open-label trial. All patient data will be handled confidentially, and anonymization will be ensured during data collection, analysis, and reporting.
Shaheed Mohtarma Benazir Bhutto Institue of Trauma is the lead sponsor of 12 studies on the registry; 8 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Participants receive a fixed pillow height of 4 cm to align the head for laryngoscopy.
Device: Group A - Fixed Pillow
Participants receive a customized pillow height of 4-8 cm to align the external auditory meatus and sternal notch.
Device: Group B - Customized Pillow
Fixed pillow height of 4 cm for laryngoscopy alignment
Pillow with adjustable height 4-8 cm to align external auditory meatus and sternal notch for laryngoscopy.
First-Attempt Intubation Success Rate
Percentage of patients in whom successful intubation is achieved on the first attempt using the study device.
Time frame: During the procedure
Heart Rate
Heart rate measured to assess physiological response to intubation. Units of Measure: Beats per minute (bpm)
Time frame: 0, 3, and 5 minutes after intubation
Intubation Time
Total time taken for successful endotracheal intubation, including multiple attempts if necessary.
Time frame: Measured during the procedure (from laryngoscope insertion to confirmation via end-tidal CO₂)
Blood Pressure
Systolic and diastolic blood pressure measured to assess physiological response. Units of Measure: mmHg
Time frame: 0, 3, and 5 minutes after intubation
Cormack-Lehane Grade
Laryngeal view graded according to the Cormack-Lehane classification by the primary investigator.
Time frame: During laryngoscopy
Documents are hosted by the registry — open the source record to download them.
Plan to share: No — Individual participant data will not be shared. Patient confidentiality, institutional policies, and local regulations regarding personal health information prevent sharing of the raw data.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
No contact was published for this record. The registry link below has the sponsor’s details.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Shaheed Mohtarma Benazir Bhutto Institue of Trauma