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CompletedNCT07468240MINDEXUpdated Mar 12, 2026

Mindfulness-Based Psychoeducation for Burnout, Decision-Making, and Existential Anxiety in High-Risk Unit Nurses

An interventional study of Mindfulness-Based Psychoeducational Program in Burnout, Clinical Decision-making and Existential Anxiety, sponsored by Duzce University. Completed at 1 site in Turkey (Türkiye). Per ClinicalTrials.gov, last updated 2026-03-12.

Sponsored by Duzce University · Not applicable, Interventional, and Prevention

From the registry’s dates

  • Registered 7 months after the study started (first participant enrolled Jun 2025, registered Jan 2026).
Phase
Not applicable
Study type
Interventional
Enrollment
66
Allocation
Randomized
Sex
All
01

Study summary

High-risk units, including intensive care, oncology, and emergency services, are clinical environments characterized by rapid decision-making demands and heavy workloads, placing substantial emotional and physical strain on nurses and other healthcare professionals. These challenging working conditions may contribute to burnout, negatively influence clinical decision-making processes, and increase levels of existential anxiety. Frequent exposure to death and critical illness can intensify nurses' confrontation with themes such as meaning, responsibility, and psychological resilience within their professional roles.

Existential anxiety involves fundamental human concerns related to life, death, freedom, responsibility, and meaning, which may become more salient in high-risk healthcare settings. In recent years, mindfulness-based approaches have gained attention as effective interventions for supporting healthcare professionals. Mindfulness emphasizes present-moment awareness and a nonjudgmental attitude toward thoughts and emotions, and has been shown to help individuals cope with stress and emotional burden more adaptively.

This study aims to evaluate the effects of a mindfulness-based psychoeducation program on burnout, clinical decision-making, and existential anxiety among nurses working in high-risk units, including intensive care, oncology, and emergency services. The findings of this study are expected to contribute to the development of supportive interventions that may enhance nurses' psychological well-being, professional functioning, and the overall quality of patient care.

02

Conditions studied

  • Burnout
  • Clinical Decision-making
  • Existential Anxiety

Keywords

  • Burnout, Professional
  • Anxiety, Existential
  • Clinical Decision-Making
  • Mindfulness
  • Nurses
03

In context

Burnout, Psychological

442 studies on the registry are indexed under Burnout, Psychological; 106 are open to participants now.

This study's enrollment of 66 is below the median of 80 across 319 interventional studies indexed under Burnout, Psychological.

Browse Burnout, Psychological studies →

Lead sponsor

Duzce University is the lead sponsor of 70 studies on the registry; 12 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Registered nurses working in high-risk clinical units, including intensive care units, oncology departments, and emergency services.
  • Having at least one year of professional nursing experience.
  • Willingness to participate in the study on a voluntary basis, with provision of informed consent.

Exclusion criteria

Exclusion Criteria:

  • Having a current or past diagnosis of a psychiatric disorder, such as schizophrenia, major depressive disorder, or bipolar disorder.
  • Inability to complete the intervention program, defined as attendance of less than 70% of the scheduled sessions.
  • Being pregnant or in the postpartum period, due to potential physical and psychological vulnerability during these stages.
  • Presence of active suicidal ideation or a history of severe psychological trauma.
  • Current use of psychoactive medication or ongoing intensive psychological treatment, including psychotherapy and/or pharmacological interventions.
  • Previous participation in a mindfulness-based psychoeducational program.
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
66 participants (actual)

Study arms

  • Experimental
    Mindfulness-Based Psychoeducation Program

    Participants receive a mindfulness-based psychoeducational program.

    Behavioral: Mindfulness-Based Psychoeducational Program

  • No intervention
    No Intervention

    Participants receive no intervention during the study period.

Interventions

  • BehavioralMindfulness-Based Psychoeducational Program

    The mindfulness-based psychoeducational program is a structured, group-based intervention designed for nurses working in high-risk hospital units. The program includes mindfulness practices, psychoeducational content, and experiential exercises aimed at enhancing awareness, emotional regulation, and adaptive coping with work-related psychological challenges.

06

What researchers measure

Primary outcomes

  1. Burnout

    Burnout Scale - Short Version: The scale was developed by Maslach and Pines (2005) to assess individuals' levels of burnout and was adapted into Turkish by Tümkaya et al. (2009), who conducted validity and reliability analyses. The Short Version of the Burnout Scale is a unidimensional instrument consisting of 10 items rated on a seven-point Likert scale (1 = never, 2 = almost never, 3 = rarely, 4 = sometimes, 5 = often, 6 = very often, 7 = always). Higher scores obtained from the scale indicate higher levels of burnout. In the Turkish adaptation study conducted by Tümkaya et al. (2009), the Cronbach's alpha coefficient was reported as 0.91 (Tümkaya, Sabahattin, \& Çavuşoğlu, 2009).

    Time frame: 12 weeks

Secondary outcomes

  1. Clinical decision-making

    Nursing Anxiety and Self-Confidence with Clinical Decision Making (NASC-CDM©) Scale: The NASC-CDM© was developed by White and adapted into Turkish by Bektaş et al. The 27-item, six-point Likert scale assesses self-confidence and anxiety separately in clinical decision-making. Both subscales include three dimensions: (1) using resources and listening fully to obtain information, (2) using available information to identify the problem, and (3) knowing and taking action. Higher scores on the self-confidence subscale indicate greater clinical decision-making confidence, whereas lower scores on the anxiety subscale indicate lower anxiety. Scores for each subscale range from 27 to 162. In the Turkish study, Cronbach's alpha was 0.97 (self-confidence) and 0.96 (anxiety). In the present study, alpha coefficients were 0.98 and 0.94, respectively.

    Time frame: 12 weeks

Other outcomes

  1. Existential anxiety

    Existential Concerns Questionnaire (ECQ): The original form of the scale was developed by van Bruggen, Klooster, Westerhof, Vos, Kleine, Bohlmeijer, and Glas (2017), and it was adapted into Turkish by Ümmet, Ekşi, Özkapu, and Ekşi (2018). The ECQ consists of 22 items rated on a five-point Likert scale and includes three subscales: general existential anxiety (13 items), death anxiety (5 items), and avoidance (4 items). Total scores range from 22 to 110, with higher scores indicating higher levels of existential anxiety. In reliability analyses, the test-retest coefficients were reported as 0.81 for the general anxiety subscale, 0.73 for the death anxiety subscale, 0.69 for the avoidance subscale, and 0.87 for the total scale. Cronbach's alpha coefficients were 0.85 for general anxiety, 0.72 for death anxiety, 0.62 for avoidance, and 0.88 for the total scale (Ümmet et al., 2018).

    Time frame: 12 weeks

07

Study locations

1 site
  • Düzce University Hospital
    Düzce, Centre 81000, Turkey (Türkiye)
08

References and documents

Individual participant data

Plan to share: No — Individual participant data will not be shared due to ethical considerations and the sensitive nature of psychological data collected from participants.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 12, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07468240
Lead sponsor
Duzce University
Responsible party
Sponsor
First posted
Mar 12, 2026
Start date
Jun 1, 2025
Primary completion
Dec 22, 2025
Completion
Dec 22, 2025
Last update
Mar 12, 2026

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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