An interventional study of Partial Wrist Denervation in Comminuted articular Distal Radius Fractures in Parial Denervation and Fracture Disatl Radius, sponsored by Assiut University. Active, not recruiting at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-02-06.
Sponsored by Assiut University · Not applicable, Interventional, and Prevention
the aim of Partial Wrist Denervation in Comminuted articular Distal Radius Fractures is to decrease incidence of chronic wrist pain follwing this type of fracture
Distal radius fractures represent the most common fractures in adults showing an overall prevalence of 17.5 % with respect to all fractures. partial wrist denervation is an adjunctive procedure performed during initial fracture fixation to mitigate chronic pain by interrupting sensory innervation to the wrist joint. It targets the anterior interosseous nerve (AIN) and posterior interosseous nerve (PIN), which convey nociceptive signals from the radiocarpal and midcarpal joints.
Comminuted intra-articular distal radius fractures (AO/OTA Type C2/C3) often lead to post-traumatic arthritis due to articular incongruity and capsular damage. Denervation at the index procedure may reduce central sensitization and chronic pain by resecting afferent pain fibers, potentially improving postoperative rehabilitation and functional outcomes.
Acute comminuted intra-articular distal radius fractures (AO/OTA C2/C3) with high risk of post-traumatic arthritis (e.g., articular step-off >2 mm, severe fragmentation).
Assiut University is the lead sponsor of 4,901 studies on the registry; 2,098 are open to participants now.
Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Inclusion Criteria:• Age from 18
Exclusion Criteria:Active local infection over the surgical site.
Partial Wrist Denervation in Comminuted articular Distal Radius Fractures
Procedure: Partial Wrist Denervation in Comminuted articular Distal Radius Fractures
Partial Wrist Denervation in Comminuted articular Distal Radius Fractures through sme approach of the surgery
The end results PAIN will be assessed according to mayo clinc wrist score
mayo clinc wrist score its a clincal reported outcome measure designed to assess function and pain of the wrist follwing surgery the score is bassed on 100 points divided into four equally weighted categories the final score places the wrist into outcome category total score 90/100 is excellent while below 65 is poor
Time frame: 2 weeks, 6 weeks, 3 months, 6 months..and 1 year
Plan to share: Undecided — will wait till we see the result
This study is active, not recruiting, as verified in Jan 2026. You cannot join it, but the record below documents what was studied.
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Assiut University