An observational study in Autonomic Nervous System Activity, Cardiovascular and Physical Activity Level, sponsored by Beijing Sport University. Not yet recruiting. Open to participants aged 18 Years to 30 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-01-22.
Sponsored by Beijing Sport University · Observational
This study aims to investigate the differences in cardiovascular stress response patterns among individuals with various physical activity levels (sedentary controls and different types of athletes). By synchronously monitoring ECG, heart rate, skin sympathetic nerve activity (SKNA), blood pressure, and cardiac output, the study will characterize physiological dynamics during resting, orthostatic challenge, cold pressor stress, and maximal exercise.
Participants will be categorized into five groups based on their training background: sedentary, endurance, strength, technical, and traditional ethnic sports. The experimental protocol includes baseline measurements in lying, standing, and sitting positions, followed by a series of acute stress tests: a lie-to-stand orthostatic test, a slow breathing test, and a cold pressor test. Finally, participants will perform a ramp incremental exercise test on a cycle ergometer. Synchronous physiological data including HRV and SKNA will be collected to evaluate the dynamic regulation of the autonomic nervous system.
Beijing Sport University is the lead sponsor of 51 studies on the registry; 9 are open to participants now.
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The study population consists of 60-80 healthy adult volunteers (college students). Participants are categorized into five distinct groups based on their habitual physical activity levels and training backgrounds: 1) Sedentary controls, 2) Endurance athletes, 3) Strength athletes, 4) Technical athletes, and 5) Traditional ethnic sports practitioners (e.g., Tai Chi). Gender balance is maintained across all groups.
Healthy young adults aged 18-25 years
Body Mass Index (BMI) within the range of 18.5-23.9 kg/m 2
No history of systematic professional athletic training (for sedentary group) or confirmed training background (for athlete groups)
No exercise contraindications or history of cardiovascular, respiratory, or metabolic diseases
No family history of sudden cardiac death
Ability to understand the study protocol and sign the informed consent form
Exclusion Criteria:
History of limb sports injury within the past 6 months or unhealed fractures
Habits of smoking or chronic alcohol consumption
Presence of implanted electronic devices (e.g., pacemakers)
Clinical diagnosis of psychiatric disorders such as anxiety or depression
Recent use of medications affecting autonomic or cardiovascular function
Regular practice of meditation or ongoing psychotherapy
Irregular menstrual cycles (for female participants)
Peripheral neuropathy or other autonomic nervous system disorders
Healthy adults with minimal physical activity, screened via SBQ and IPAQ-S questionnaires as baseline controls
Diagnostic Test: Cardiopulmonary Exercise Testing
Long-distance runners or triathletes with over 1 year of regular aerobic training (e.g., 800m+ running, swimming).
Diagnostic Test: Cardiopulmonary Exercise Testing
Athletes specializing in anaerobic/power-based training, such as weightlifting, wrestling, or sprinting.
Diagnostic Test: Cardiopulmonary Exercise Testing
Practitioners of mind-body exercises like Tai Chi or Baduanjin, emphasizing respiratory control and mild intensity
Diagnostic Test: Cardiopulmonary Exercise Testing
Cardiopulmonary Exercise Testing (CPET) is a non-invasive, integrated assessment of the cardiovascular, respiratory, and muscular systems' responses to physical stress.
Heart Rate Variability
Time-domain metrics (e.g., RMSSD, SDNN) derived from ECG recordings to evaluate cardiovagal modulation and cardiac autonomic balance.
Time frame: Baseline (10-minute rest), during the 10-minute mental stress test, and during the cardiopulmonary exercise test (approx. 20 minutes)
Skin Sympathetic Nerve Activity
Integrated average SKNA (aSKNA) and burst metrics measured via surface electrodes to assess sympathetic nerve firing
Time frame: Baseline (10-minute rest), during the 10-minute mental stress test, and during the cardiopulmonary exercise test (approx. 20 minutes)
No study locations are listed for this record.
Plan to share: Undecided
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in Jan 2026. You cannot join it, but the record below documents what was studied.
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Beijing Sport University