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Not yet recruitingNCT07339683NPUpdated Jan 14, 2026

Influence of Cervical Stabilization Exercises on Neural Tissue Mechanosensitivity in Patients With Chronic Nonspecific Neck Pain

An interventional study of cervical and scapulothoracic stabilization exercises. and traditional therapy in Neck Pain, sponsored by Cairo University. Not yet recruiting. Open to participants aged 18 Years to 36 Years. Per ClinicalTrials.gov, last updated 2026-01-14.

Sponsored by Cairo University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Jun 2026, 3 months ago, but the record still lists the study as not yet recruiting.
Phase
Not applicable
Study type
Interventional
Enrollment
80
Allocation
Randomized
Ages
18 Years to 36 Years
Sex
All
01

Study summary

this study will be conducted to investigate the effect of cervical stabilization exercises on cervical pain intensity, upper limbs mechanosensitivity, cervicovertebral angle, and cervical proprioception in individuals with chronic nonspecific neck pain

Read the detailed description

Neck pain is the sensation of discomfort in the neck area. Neck pain can result from disorders of any of the structures in the neck, including the cervical vertebrae and intervertebral discs, nerves, muscles, blood vessels, esophagus, larynx, trachea, lymphatic organs, thyroid gland, or parathyroid glands.Forward head posture (FHP) is one of the commonly recognized types of poor head posture in the sagittal plane in patients with neck pain. FHP has been defined as 'any alignment in which the external auditory meatus is positioned anterior to the plumb line through the shoulder joint, with a general prevalence of about 64% in both males and females.Several studies reported the effect of cervical stabilization exercises on pain, ROM and cranio-cervical angle in patients with chronic non-specific neck pain. No studies have been concerned with measuring mechanosensitivity as an indicator technique of the effect of different modalities on chronic non-specific neck pain. With the proposal of the cervical and scapulothoracic stabilization program for patients with chronic non-specific neck pain secondary to forward head posture deviations.

02

Conditions studied

  • Neck Pain

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Keywords

  • cervical stabilization
  • tissue mechanosensitivity
  • neck pain
03

In context

Neck Pain

1,232 studies on the registry are indexed under Neck Pain; 255 are open to participants now.

This study's planned enrollment of 80 is above the median of 52 across 1,004 interventional studies indexed under Neck Pain.

Browse Neck Pain studies →

Lead sponsor

Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.

Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 36 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • participants with age range from 18 to 36 years and BMI from 25 to 30kg/m2 will be recruited
  • Participants having neck pain symptoms provoked by neck postures, neck movement, or palpation of the cervical musculature, for 3 months
  • Patients with a craniovertebral angle of less than 50º

Exclusion criteria

Exclusion Criteria:

  • History of previous injury of the neck.
  • History of surgical intervention at the neck.
  • History of inflammatory joint disease affecting facet joints
  • participants with congenital disorders of the cervical spine.
  • participants who received pain medication or physical therapy for their neck pain during the last 3 months.
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
80 participants (estimated)

Study arms

  • Experimental
    cervical and scapulothoracic stabilization exercises.

    forty patients will receive cervical and scapulothoracic stabilization exercises plus traditional therapy three times a week for six weeks

    Other: cervical and scapulothoracic stabilization exercises. · Other: traditional therapy

  • Active comparator
    traditional therapy

    forty patients will receive traditional therapy three times a week for six weeks

    Other: traditional therapy

Interventions

  • Othercervical and scapulothoracic stabilization exercises.

    the patients will receive cervical and scapulothoracic stabilization exercises in the form of activation of deep cervical flexors in the first two weeks, followed by scapulothoracic muscles activation for the third and fourth weeks and finally group of exercises that emphasis on increasing difficulty and progress to quadruped and standing.

  • Othertraditional therapy

    the patients will receive traditional therapy in the form of ultrasound, hot pack, cervical extensors stretching and deep flexor strengthening

06

What researchers measure

Primary outcomes

  1. mechanosensitivity of upper limb nerves

    A handheld algometer will be used to assess mechanosensitivity. To apply this test test, specific points on the peripheral nerve trunks of the tested upper limb nerves will be identified through manual palpation, being easily accessible by the probe of the algometer and as they are commonly used sites of peripheral nerves' palpation with moderate inter-tester reliability. The supine lying posture will be assumed to test median and ulnar nerves, while sitting posture will be the choice for radial nerve. Median nerve will be located and tested in the antebrachial fossa just medial to the biceps brachii tendon. Ulnar will be tested in the cubital tunnel between humeral medial epicondyle and olecranon process, with the arm in 90º shoulder abduction as well as external rotation, and elbow flexion. Radial nerve palpation point lies between the middle and lower thirds of the humerus.

    Time frame: up to 6 weeks

Secondary outcomes

  1. craniovertebral angle

    craniovertebral angle will be assessed by Kinovia software. Forward head posture will be determined when the craniovertebral angle is below 50 degrees (normal value).

    Time frame: up to 6 weeks

  2. pain intensity

    Visual analogue scale is the most commonly used method for assessing pain intensity. The left most value on the 10-cm horizontal line used for visual analogue scale indicates a painless condition, which is represented by 0. The rightmost value is 10, which represents extreme pain. The subjects will be in a relaxed position then will give them the appendix which contains VAS and rate their feelings of pain on the line by themselves, thereby quantifying the pain

    Time frame: up to six weeks

  3. cervical joint position error (cervical proprioception)

    To evaluate the joint position error , the examiner will hold the subject's head and moving slowly to the target head position, which is 50% of the maximum CROM and hold there for a period of 3 s. The subjects then memorized that target position and then the examiner slowly brought the subject's head back to the neutral position. The subjects then will be advised to reach the target position actively by moving the head and when subject reached the target position the reposition accuracy error will determine in degrees. The examiner will evaluate JPE tests in sagittal (flexion, extension) and transverse plane (right and left rotation) directions. Each direction of JPE testing will be performed three times and the mean error of these trials will be used in the analysis

    Time frame: up to six weeks

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 14, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07339683
Lead sponsor
Cairo University
Responsible party
nada ashraf mohamed zuhairy (principle investigator : nada ashraf mohamed zuhairy, Cairo University) — Principal investigator
First posted
Jan 14, 2026
Start date
Jan 15, 2026 (estimated)
Primary completion
Jun 15, 2026 (estimated)
Completion
Jun 25, 2026 (estimated)
Last update
Jan 14, 2026

Study contacts

nada zuhairy, phd
Contact
nadazuhairy11@gmail.com
01014930018

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Jan 2026. You cannot join it, but the record below documents what was studied.

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