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RecruitingNCT07325344Updated Jan 8, 2026

Active Locomotion of Magnetically Controlled Capsule Endoscopy in the Small Bowel: A Feasibility Study

An interventional study of magnetic control in Capsule Endoscopy, sponsored by Shandong University. Recruiting at 1 site in China. Per ClinicalTrials.gov, last updated 2026-01-08.

Sponsored by Shandong University · Not applicable, Interventional, and Other

Phase
Not applicable
Study type
Interventional
Enrollment
15
Allocation
Not applicable
Sex
All
01

Study summary

The aim of this study is to evaluate the responsiveness of the capsule endoscope to the attitude controller and to investigate its active locomotion performance within the small bowel.

Read the detailed description

During the standard air insufflation or water infusion phases of double-balloon enteroscopy, researchers will use a handheld controller to try to steer the capsule. At the same time, the real-time imaging from both the enteroscope and the capsule will be simultaneously monitored to assess the capsule's active movement and its responsiveness to control.

02

Conditions studied

  • Capsule Endoscopy

Keywords

  • capsule endoscopy
  • small bowel disease
  • locomotion
03

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patients scheduled to undergo enteroscopy.

Exclusion criteria

Exclusion Criteria:

  • Patients with severe dysfunction of vital organs (e.g., heart, lungs). Patients with small bowel obstruction precluding adequate bowel preparation. Patients with a history of multiple abdominal surgeries. Patients with implanted devices such as cardiac pacemakers or metal implants. Patients with other high-risk conditions or lesions (e.g., moderate-to-severe esophagogastric varices, massive ascites).

Patients who are pregnant or lactating. Patients unable or unwilling to provide informed consent.

04

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
15 participants (estimated)

Study arms

  • Experimental
    subject

    During the routine air/water insufflation phases of the enteroscopy, the researchers will attempt to guide the capsule's movement using an external magnetic control device.

    Device: magnetic control

Interventions

  • Devicemagnetic control

    Intervention: On the day of the examination, the subject will swallow the capsule endoscope. This will be followed by a standard enteroscopy procedure. During the routine air/water insufflation phases of the enteroscopy, the researchers will attempt to guide the capsule's movement using an external magnetic control device.

05

What researchers measure

Primary outcomes

  1. capsule endoscope's responsiveness to the attitude controller

    Excellent: The magnetically controlled capsule endoscope can precisely follow the attitude controller to move to the target area. Moderate: The magnetically controlled capsule endoscope can follow the attitude controller's movement, but cannot be accurately guided to the target area. Poor: There are signs of magnetic attraction, but the capsule does not follow the movement of the attitude controller.

    Time frame: During performing double-balloon enteroscope

06

Study locations

1 of 1 sites recruiting
  • Qilu Hospital of Shandong University
    Jinan, Shandong 250012, China
    Recruiting
07

Registry details

Key details

Study ID
NCT07325344
Lead sponsor
Shandong University
Responsible party
Xiuli Zuo (Director of Gastroenterology Department, Qilu Hospital of Shandong University) — Principal investigator
First posted
Jan 8, 2026
Start date
Dec 1, 2025
Primary completion
Dec 31, 2026 (estimated)
Completion
Dec 31, 2026 (estimated)
Last update
Jan 8, 2026

Study contacts

Xiuli Zuo, MD,PhD
Contact
zuoxiuli@sdu.edu.cn
+86-18560080066

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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