An interventional study of biaural beat and control in Breast Reconstruction, sponsored by Seoul National University Hospital. Not yet recruiting. Open to participants aged 19 Years and older. Per ClinicalTrials.gov, last updated 2025-12-31.
Sponsored by Seoul National University Hospital · Not applicable, Interventional, and Treatment
This prospective randomized controlled trial evaluates whether intraoperative binaural beats reduce the remimazolam dose required for general anesthesia in 88 adults undergoing breast surgery. Patients are assigned to binaural beats or silent earphones, and the primary outcome is total intraoperative remimazolam consumption.
Seoul National University Hospital is the lead sponsor of 1,860 studies on the registry; 275 are open to participants now.
Of its 12 completed or terminated interventional studies of FDA-regulated products, 2 (17%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Participants receive binaural beats via earphones from OR entry until end of surgery.
Device: biaural beat
Participants wear identical earphones but receive no audio stimulation.
Device: control
Participants receive binaural beats via earphones from OR entry until end of surgery.
Participants wear identical earphones but receive no audio stimulation.
Total intraoperative remimazolam dose
Total amount of remimazolam administered during general anesthesia
Time frame: From induction of anesthesia to end of surgery
Total intraoperative remifentanil dose
Total remifentanil administered using target-controlled infusion.
Time frame: Intraoperative period
BIS
BIS levels measured continuously.
Time frame: Intraoperative period
Postoperative analgesic use
Amount of opioids, non-opioid analgesics administered.
Time frame: PACU until Postoperative day 1
Heart rate
Heart rate during operation
Time frame: intraoperative
blood pressure
blood pressure during surgery
Time frame: intraoperative
SpO₂
saturation during surgery
Time frame: intraoperative
Postoperative antiemetic use
Amount of antiemetics administered.
Time frame: PACU until Postoperative day 1
No study locations are listed for this record.
This study is not yet recruiting, as verified in Nov 2025. You cannot join it, but the record below documents what was studied.
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Seoul National University Hospital