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CompletedNCT07308197Updated Dec 29, 2025

Effect of Posterior Colpotomy First Technique on the Vaginal Length During Total Abdominal Hysterectomy

An interventional study of Abdominal hysterectomy in Hysterectomy, Benign Uterine Diseases, sponsored by Cairo University. Completed at 1 site in Egypt. Open to female participants aged 40 Years to 65 Years. Per ClinicalTrials.gov, last updated 2025-12-29.

Sponsored by Cairo University · Not applicable, Interventional, and Prevention

From the registry’s dates

  • Registered 2 years 8 months after the study started (first participant enrolled Mar 2023, registered Dec 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
80
Allocation
Randomized
Ages
40 Years to 65 Years
Sex
Female
01

Study summary

the same surgeon performed all of the procedures using the same method. A lower midline or Pfannestiel incision is the first step in the complete abdominal hysterectomy procedure. They clamp, cut, and ligate the top pedicles. The cardinal and uterosacral ligaments were dissected, the wide ligament's leaves were cut, the bladder was carefully lowered, and the uterine vessels were skeletonized, cut, and tied. Group A (traditional technique): the surgeon makes a circumferential incision after initially entering the front vaginal wall. The surgeon performs a circumferential colpotomy at the topmost section of the vagina using the Group B (posterior colpotomy first) approach, entering the vagina via the posterior wall at the uppermost part of the uterosacral ligaments, followed by the left lateral fornix.

Reconstruction of the pelvic floor to ensure hemostasis and good pelvic support. The operative time was assessed by calculating the time between vaginal cuff opening and suturing after uterine artery ligation, As point D on the POP-Q system is omitted after hysterectomy, point C level was reassessed 2 weeks postoperative.

Read the detailed description

the same surgeon performed all of the procedures using the same method. A lower midline or Pfannestiel incision is the first step in the complete abdominal hysterectomy procedure. They clamp, cut, and ligate the top pedicles. The cardinal and uterosacral ligaments were dissected, the wide ligament's leaves were cut, the bladder was carefully lowered, and the uterine vessels were skeletonized, cut, and tied. Group A (traditional technique): the surgeon makes a circumferential incision after initially entering the front vaginal wall. The surgeon performs a circumferential colpotomy at the topmost section of the vagina using the Group B (posterior colpotomy first) approach, entering the vagina via the posterior wall at the uppermost part of the uterosacral ligaments, followed by the left lateral fornix.

Reconstruction of the pelvic floor to ensure hemostasis and good pelvic support. The operative time was assessed by calculating the time between vaginal cuff opening and suturing after uterine artery ligation, As point D on the POP-Q system is omitted after hysterectomy, point C level was reassessed 2 weeks postoperative.

Total vaginal shortening (TVS) and vaginal shortening ratio (VSR) were calculated according to the formulas given below.

TVS=Preoperative VL-Postoperative VL at 3 months. VSP=Preoperative VL-Postoperative VL at 3 months\ Preoperative VL*100

02

Conditions studied

  • Hysterectomy, Benign Uterine Diseases

Keywords

  • hystrectomy
  • posterior colopotomy
  • Vaginal length
03

In context

Lead sponsor

Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.

Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
40 Years to 65 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Inclusion criteria

  • Ages 40 - 65 years
  • sexually active
  • BMI of 25-40 kg/m2
  • had a fresh abdomen
  • had a benign reason for a hysterectomy (multiple fibroid uterus, adenomyosis, or endometrial hyperplasia).

Exclusion criteria

Exclusion Criteria:

  • Patients who had vaginal and uterine prolapse,
  • subtotal hysterectomy,
  • caesarean hysterectomy in patients with major obstetric hemorrhage (placenta previa, accreta-increta-percreta, uncontrolled postpartum hemorrhage)
  • malignant indications of total abdominal hysterectomy (uterine and cervical carcinoma)
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
80 participants (actual)

Study arms

  • Active comparator
    Group A (Classic technique):

    the surgeon makes a circumferential incision after initially entering the front vaginal wall. The surgeon performs a circumferential colpotomy at the topmost section of the vagina

    Procedure: Abdominal hysterectomy

  • Active comparator
    Group B (posterior colpotomy first) approach

    entering the vagina via the posterior wall at the uppermost part of the uterosacral ligaments, followed by the left lateral fornix

    Procedure: Abdominal hysterectomy

Interventions

  • ProcedureAbdominal hysterectomy

    A lower midline or Pfannestiel incision is the first step in the complete abdominal hysterectomy procedure. They clamp, cut, and ligate the top pedicles. The cardinal and uterosacral ligaments were dissected, the wide ligament's leaves were cut, the bladder was carefully lowered, and the uterine vessels were skeletonized, cut, and tied

06

What researchers measure

Primary outcomes

  1. Total vaginal length

    calculated according to the formula TVS=Preoperative VL-Postoperative VL

    Time frame: after 3 months

07

Study locations

1 site
  • Cairo university
    Cairo, Cairo Governorate 12111, Egypt
08

References and documents

Publications

  • Farid MN, Hammad BM, Saad H, Abdelfattah AA, Maged AM, Soliman MR. The value of posterior colpotomy first technique on the vaginal length during total abdominal hysterectomy. BMC Womens Health. 2026 May 1;26(1):232. doi: 10.1186/s12905-026-04476-1. PubMed 42063059 ↗

Individual participant data

Plan to share: Undecided

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 29, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07308197
Lead sponsor
Cairo University
Responsible party
Ahmed M Maged, MD (Professor, Cairo University) — Principal investigator
First posted
Dec 29, 2025
Start date
Mar 30, 2023
Primary completion
Mar 25, 2024
Completion
Sep 16, 2024
Last update
Dec 29, 2025

Study contacts

Ahmed Maged
principal investigator · Cairo University

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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